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enflurane and Hypoxia

enflurane has been researched along with Hypoxia in 21 studies

Enflurane: An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.
enflurane : An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"2 minimum alveolar concentration (MAC) of enflurane on the time course of ventilation during sustained hypoxia, we studied 10 healthy adult volunteers with and without enflurane."7.69Influence of 0.2 minimum alveolar concentration of enflurane on the ventilatory response to sustained hypoxia in humans. ( Dorrington, KL; Nagyova, B; Poulin, MJ; Robbins, PA, 1997)
"To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane."7.67Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs. ( Butler, BD; Katz, J; Leiman, BC, 1987)
"2 minimum alveolar concentration (MAC) of enflurane on the time course of ventilation during sustained hypoxia, we studied 10 healthy adult volunteers with and without enflurane."3.69Influence of 0.2 minimum alveolar concentration of enflurane on the ventilatory response to sustained hypoxia in humans. ( Dorrington, KL; Nagyova, B; Poulin, MJ; Robbins, PA, 1997)
"The authors' aim was to examine direct cardiac responses to isoflurane, enflurane and halothane, as altered during mild hypoxia by the substitution of nitrogen (N2) for oxygen (O2), and additionally by the substitution of nitrous oxide (N2O) for N2."3.68Comparison of halothane, enflurane, and isoflurane with nitrous oxide on contractility and oxygen supply and demand in isolated hearts. ( Bosnjak, ZJ; Kampine, JP; Marijic, J; Monroe, SM; Stowe, DF, 1991)
"To evaluate the effects of succinylcholine on cardiac arrhythmias and serum levels of potassium and catecholamines, dogs with hypoxia alone and with hypoxia and hypercarbia were studied during anesthesia with halothane or enflurane."3.67Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs. ( Butler, BD; Katz, J; Leiman, BC, 1987)
"A rat model of enflurane-associated hepatotoxicity was compared with the halothane-hypoxia (HH) model (adult male rats, phenobarbital induction, 1% halothane, 14% O2, for 2 hr)."3.67Comparison of the requirements for hepatic injury with halothane and enflurane in rats. ( Brown, BR; Gandolfi, AJ; Lind, RC; Sipes, IG, 1985)
"To assess the impact of surgical stimulation on regulation of ventilation in anaesthetized man, we measured ventilation and the ventilatory responses to either hyperoxic hypercapnia or to isocapnic hypoxaemia in fifteen subjects anaesthetized with enflurane 1."3.66Surgical stimulation does not enhance ventilatory chemoreflexes during enflurane anaesthesia in man. ( Clement, JL; Knill, RL; Lam, AM, 1980)
"The ventilatory responses to isocapnic hypoxia and hypercapnia were studied in six dogs each with a tracheostomy, awake and during anaesthesia with halothane, enflurane and isoflurane (1-2."3.65Depression of hypoxic ventilatory response by halothane, enflurane and isoflurane in dogs. ( Cohen, PJ; Hirshman, CA; McCullough, RE; Weil, JV, 1977)
"Glutamate released during hypoxia or anoxia was 1."1.29Volatile and intravenous anesthetics decrease glutamate release from cortical brain slices during anoxia. ( Bickler, PE; Buck, LT; Feiner, JR, 1995)
" In Study II a dose-response curve was established for the potent stimulator (Sin 1) of the enzyme guanylate cyclase."1.28Endothelium-derived relaxing factor is not responsible for inhibition of hypoxic pulmonary vasoconstriction by inhalational anesthetics. ( Marshall, BE; Marshall, C, 1990)
"Enflurane was the most potent myocardial depressor and isoflurane the most potent vasodilator, halothane being intermediate."1.27Cardiovascular and blood gas responses to inhaled anaesthetics in normoxic and hypoxic dogs. ( Deloof, T; Lambert, M; Leeman, M; Lejeune, P; Naeije, R, 1986)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199014 (66.67)18.7374
1990's7 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jurdi-Nuwayhid, F1
Mebius, C1
Hedenstierna, G2
Data, PG1
Di Tano, G1
Cacchio, M1
Della Valle, R1
Lam, AM1
Clement, JL1
Knill, RL3
Bjertnaes, LJ1
Mundal, R1
Stadnicka, A1
Stekiel, TA1
Hogan, QH1
Bosnjak, ZJ2
Kampine, JP2
Bickler, PE1
Buck, LT1
Feiner, JR1
Nagyova, B1
Dorrington, KL1
Poulin, MJ1
Robbins, PA1
Mathers, J1
Benumof, JL1
Wahrenbrock, EA1
Manninen, P1
Hirshman, CA1
McCullough, RE1
Cohen, PJ1
Weil, JV1
Stowe, DF1
Monroe, SM1
Marijic, J1
Jenkins, IR1
Marshall, C1
Marshall, BE1
Abballe, C1
Sabato, AF1
Stefanelli, A1
Calimici, R1
Morelli Sbarra, G1
Leiman, BC1
Katz, J1
Butler, BD1
Naeije, R1
Lambert, M1
Lejeune, P1
Leeman, M1
Deloof, T1
Carlsson, AJ1
Bindslev, L1
Gelman, S1
Lind, RC1
Gandolfi, AJ1
Sipes, IG1
Brown, BR1

Other Studies

21 other studies available for enflurane and Hypoxia

ArticleYear
Untoward side effects and toxicities of inhalational anesthetics.
    Middle East journal of anaesthesiology, 1984, Volume: 7, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics; Carcinogens; Chemical and Drug Induced Liver Injury; Enflurane;

1984
Airway closure and distribution during hip arthroplasty.
    Acta anaesthesiologica Scandinavica, 1982, Volume: 26, Issue:1

    Topics: Adult; Aged; Airway Obstruction; Anesthesia, General; Enflurane; Female; Functional Residual Capacit

1982
[Hemodynamic modifications induced by volatile anesthetics halothane, penthrane, ethrane). II. Effect on myocardial contraction and myocardial response to hypoxia].
    Bollettino della Societa italiana di biologia sperimentale, 1981, Mar-15, Volume: 57, Issue:5

    Topics: Anesthetics; Animals; Coronary Circulation; Dogs; Enflurane; Halothane; Heart; Hemodynamics; Hypoxia

1981
Surgical stimulation does not enhance ventilatory chemoreflexes during enflurane anaesthesia in man.
    Canadian Anaesthetists' Society journal, 1980, Volume: 27, Issue:1

    Topics: Adult; Carbon Dioxide; Chemoreceptor Cells; Enflurane; Humans; Hypercapnia; Hypoxia; Oxygen; Respira

1980
The pulmonary vasoconstrictor response to hypoxia during enflurane anesthesia.
    Acta anaesthesiologica Scandinavica, 1980, Volume: 24, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Enflurane; Hypoxia; Lung; Rats; Vasoconstriction

1980
Hypoxic contraction of isolated rabbit mesenteric veins. Contribution of endothelium and attenuation by volatile anesthetics.
    Anesthesiology, 1995, Volume: 82, Issue:2

    Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Enflurane; Glycopeptides; Halothane; Hypoxi

1995
Interpreting low-dose anesthetic effects on the ventilatory response to hypoxemia: facts, findings, and fanciful formulations.
    Anesthesiology, 1994, Volume: 81, Issue:4

    Topics: Anesthetics; Dose-Response Relationship, Drug; Enflurane; Halothane; Humans; Hypoxia; Isoflurane; Re

1994
Volatile and intravenous anesthetics decrease glutamate release from cortical brain slices during anoxia.
    Anesthesiology, 1995, Volume: 83, Issue:6

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cerebral Cortex; Enflurane; Glutamic Aci

1995
Influence of 0.2 minimum alveolar concentration of enflurane on the ventilatory response to sustained hypoxia in humans.
    British journal of anaesthesia, 1997, Volume: 78, Issue:6

    Topics: Adult; Anesthetics, Inhalation; Carbon Dioxide; Enflurane; Humans; Hypoxia; Middle Aged; Oxygen; Par

1997
General anesthetics and regional hypoxic pulmonary vasoconstriction.
    Anesthesiology, 1977, Volume: 46, Issue:2

    Topics: Anesthesia, Endotracheal; Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Dogs; Dose-Re

1977
Cardiovascular signs of acute hypoxaemia and hypercarbia during enflurane and halothane anaesthesia in man.
    Canadian Anaesthetists' Society journal, 1979, Volume: 26, Issue:4

    Topics: Adult; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxide; Enflurane; Halothane; Heart Rate; Hum

1979
Depression of hypoxic ventilatory response by halothane, enflurane and isoflurane in dogs.
    British journal of anaesthesia, 1977, Volume: 49, Issue:10

    Topics: Anesthesia; Animals; Carbon Dioxide; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; E

1977
Comparison of halothane, enflurane, and isoflurane with nitrous oxide on contractility and oxygen supply and demand in isolated hearts.
    Anesthesiology, 1991, Volume: 75, Issue:6

    Topics: Animals; Coronary Circulation; Enflurane; Guinea Pigs; Halothane; Heart Conduction System; Heart Rat

1991
A 'too close to the door' knob.
    Anaesthesia and intensive care, 1991, Volume: 19, Issue:4

    Topics: Adolescent; Anesthesia, Inhalation; Enflurane; Equipment Design; Equipment Failure; Humans; Hypoxia;

1991
Endothelium-derived relaxing factor is not responsible for inhibition of hypoxic pulmonary vasoconstriction by inhalational anesthetics.
    Anesthesiology, 1990, Volume: 73, Issue:3

    Topics: Animals; Enflurane; Female; Halothane; Hypoxia; In Vitro Techniques; Isoflurane; Lung; Nitric Oxide;

1990
[Hypoxia and protection of the brain (isoflurane vs halothane and enflurane].
    Minerva anestesiologica, 1987, Volume: 53, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Brain Diseases; Enflurane; Female; Halothane; Hypoxia; Isoflurane;

1987
Mechanisms of succinylcholine-induced arrhythmias in hypoxic or hypoxic:hypercarbic dogs.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:12

    Topics: Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Dogs; Enflurane; Epinephrine; Halothane; Hype

1987
Cardiovascular and blood gas responses to inhaled anaesthetics in normoxic and hypoxic dogs.
    Acta anaesthesiologica Scandinavica, 1986, Volume: 30, Issue:7

    Topics: Adaptation, Physiological; Anesthesia, Inhalation; Animals; Dogs; Enflurane; Halothane; Hemodynamics

1986
Hypoxia-induced vasoconstriction in human lung exposed to enflurane anaesthesia.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:1

    Topics: Abdomen; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Enflurane; Female; Hemodynamics; Hu

1987
Are the requirements for hepatic injury with halothane and enflurane in rats really different?
    Anesthesia and analgesia, 1986, Volume: 65, Issue:5

    Topics: Animals; Enflurane; Halothane; Hypoxia; Liver; Rats

1986
Comparison of the requirements for hepatic injury with halothane and enflurane in rats.
    Anesthesia and analgesia, 1985, Volume: 64, Issue:10

    Topics: Anesthesia, Inhalation; Animals; Biotransformation; Body Temperature; Carbon Tetrachloride; Chemical

1985