Page last updated: 2024-10-26

enflurane and Ache

enflurane has been researched along with Ache in 8 studies

Enflurane: An extremely stable inhalation anesthetic that allows rapid adjustments of anesthesia depth with little change in pulse or respiratory rate.
enflurane : An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups.

Research Excerpts

ExcerptRelevanceReference
" After having established the mice model of hypnosis and analgesia by intraperitoneal injections of appropriate doses of enflurane, isoflurane or sevoflurane, we intracerebroventricularly or intrathecally injected different doses of nicotine and then observed the effects on the sleeping time using awaken test and the pain threshold in hot-plate test (HPPT) using hot-plate test."3.75Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics. ( Dai, TJ; Yan, S; Zeng, YM, 2009)
" After having established the mouse model of analgesia by intraperitoneal or subcutaneous injections of appropriate doses of emulsified enflurane, isoflurane or sevoflurane, we injected different doses of AMPA intrathecally and observed effects on the pain threshold using the hot-plate and acetic acid-induced writhing tests."3.74Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics. ( Dai, TJ; Hang, LH; Shao, DH; Yang, YH; Zeng, YM, 2007)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, LW1
Zhou, MY1
Jian, HW1
Dai, TJ4
Yan, S1
Zeng, YM3
Chen, Y1
Hang, LH1
Shao, DH1
Yang, YH1
Kissin, I1
Morgan, PL1
Tomi, K1
Mashimo, T1
Tashiro, C1
Yagi, M1
Pak, M1
Nishimura, S1
Nishimura, M1
Yoshiya, I1
Washington, DE1
Sessler, DI1
McGuire, J1
Hynson, J1
Schroeder, M1
Moayeri, A1
Alteri, S1
Beruschi, M1
Bolli, L1
Fazio, R1
Maddaloni, G1
Mammarella, M1
Mammini, R1
Paesani, G1
Poli, P1
Riccardi, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Methoxyflurane Vaporized (PENTHROX®) in the Treatment of Acute Trauma Pain in Pre-hospital Setting and in the Emergency Department in Italy: a Multicentre, Randomized, Controlled, Open-label Study[NCT03585374]Phase 3272 participants (Actual)Interventional2018-02-08Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for enflurane and Ache

ArticleYear
Painful stimulation minimally increases the thermoregulatory threshold for vasoconstriction during enflurane anesthesia in humans.
    Anesthesiology, 1992, Volume: 77, Issue:2

    Topics: Adult; Anesthesia, Inhalation; Body Temperature Regulation; Electric Stimulation; Enflurane; Female;

1992
[Evaluation of analgesic protection using RIA determination of prolactin, ACTH, cortisol and aldosterone during general anesthesia with enflurane-isoflurane and buprenorphine].
    Minerva anestesiologica, 1987, Volume: 53, Issue:11

    Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Anesthesia, General; Buprenorphine; Enflurane; Fema

1987

Other Studies

6 other studies available for enflurane and Ache

ArticleYear
Relationship between gamma-hydroxybutyric acid receptors and the hypnotic and analgesic effects of emulsified inhalation anesthetics.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:16

    Topics: Analgesics; Anesthetics, Inhalation; Animals; Benzocycloheptenes; Enflurane; Female; Hot Temperature

2014
Nicotinic acetylcholine receptors mediate the hypnotic and analgesic effects of emulsified inhalation anesthetics.
    Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane; Female; In

2009
Strychnine-sensitive glycine receptors mediate the analgesic but not hypnotic effects of emulsified volatile anesthetics.
    Pharmacology, 2007, Volume: 80, Issue:2-3

    Topics: Analgesia; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Emulsions; Enflurane;

2007
Spinal alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors may mediate the analgesic effects of emulsified halogenated anaesthetics.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:11

    Topics: Acetic Acid; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Anesthetics, Inha

2007
Heart rate response to nociceptive stimulation as an index of anesthetic potency for enflurane.
    Anesthesiology, 1983, Volume: 58, Issue:1

    Topics: Anesthesia; Animals; Dose-Response Relationship, Drug; Enflurane; Heart Rate; Pain; Rats

1983
Alterations in pain threshold and psychomotor response associated with subanaesthetic concentrations of inhalation anaesthetics in humans.
    British journal of anaesthesia, 1993, Volume: 70, Issue:6

    Topics: Adult; Anesthesia, Inhalation; Anesthetics; Enflurane; Ethers; Halothane; Humans; Isoflurane; Male;

1993