enerbol and Neoplasms

In spite of the well-known harmful effects on the fetus, many women continue smoking during pregnancy. Smoking as an important source of toxic chemicals may contribute to the developmental origin of diseases.. The aim of this work was to pursue the possible association between maternal smoking and cancer in early life. Specifically, we wanted to identify the associated early life cancer types, and to quantify the associations.. In a systematic literature search 825 articles were identified in PubMed and Web of Science, and 55 more through the reference lists. Of these 62 fulfilled the criteria for inclusion in meta-analyses. Using Mantel-Haenszel or DerSimonian and Laird method, depending on heterogeneity of the studies, pooled estimates and 95% confidence intervals for eight cancer types were calculated.. Smoking during pregnancy was associated with an increased risk for for brain and central nervous system tumors (OR = 1.09; 95% CI = 1.02-1.17). Although the risk for lymphoma was also associated (OR = 1.21; 95% CI = 1.05-1.34), it did not hold up in subgroup analyses. Leukemia was not found to be associated with maternal smoking. Five other cancer types (bone, soft tissue, renal, hepatic, and germ cell cancer) were also examined, but the number of studies was too limited to exclude the possibility of maternal smoking as a risk factor for cancer in offspring.. According to our meta-analyses, maternal smoking is associated with nervous system cancers, but not with leukemia in early life. Confirming or rejecting associations of maternal smoking with lymphoma and the five other cancer types requires further studies.

Topics: Female; Humans; Life; Neoplasms; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Smoking

The recovery of the human character and purpose of life with consciousness-based medicine seems to be able to induce spontaneous remissions in several diseases. On two different occasions, we observed breast tumors reduced to less than half their original diameters (clinically judged) during a holistic session, when working with the patients in accordance with the holistic process theory of healing, the life mission theory, and the theory of human character. One tumor was histologically diagnosed as malign breast cancer prior to the session, while the other was under examination. As both patients had the affected regions of the breast surgically removed immediately after the session, we are unable to determine if they were actually healed by the holistic treatment. We find it extremely interesting that the size of a tumor can be reduced dramatically within a few hours of holistic treatment, when the patient is highly motivated for personal development. The reduction of tumor size is in accordance with the holistic view that many types of cancer are caused by emotional and existential disturbances. From a holistic perspective, cancer can be understood as a simple disturbance of the cells, arising from the tissue holding on to a trauma with strong emotional content. This is called "a blockage", where the function of the cells is changed from their original function in the tissue to a function of holding emotions. The reduction of the tumor in the two cases happened when old painful emotions were identified in the tissues, in and around the tumor, and processed into understanding; when the patients finally did let go of negative beliefs and attitudes that had kept the feeling(s) repressed to that part of the body, the tumor first softened and then disappeared, presumably by apoptosis. We believe that the consciousness-based/holistic medical toolbox has a serious additional offer to cancer patients, and we will therefore strongly encourage the scientific society to explore these new possibilities. Our holistic medical research meets both ethical dilemmas and practical difficulties, as it obviously is important for the research in induced spontaneous remissions that surgery and chemotherapy is not used before it is absolutely necessary. On the other hand, is it important for the patient"s survival that they receive any well-documented treatment as soon as possible. An additional aspect for the patient who is able to cure her own cancer is that she is much less

Topics: Character; Clinical Medicine; Existentialism; Holistic Health; Humans; Life; Neoplasm Regression, Spontaneous; Neoplasms; Quality of Life

Films that feature characters with cancer have become a familiar sight for movie-goers. 148 movies treating tumors were selected, produced all over the world since the Thirties, in which cancer had "prompt", "relevant", or "plot" character. In order to clearly understand each film's peculiar message about cancer, we recollected data such as genealogy, year and country of production, main characters' age and gender, and kind of tumor. Movies deal with cancer through very relevant questions, as well as themes and contexts that have great influence on oncologist's mind and consciousness. Specially in recent years, films have tackled some of the most important issues around cancer, such as his epidemiology and environmental causes; the economic implications of therapies; the management of symptoms and side effects; the psychological dynamics; the care toward the ending of life. The most frequent treatment mentioned in the movies was chemotherapy followed by antalgic therapy. Very often the ill person on the screen doesn't get over the disease and his death is somehow useful to the plot's outcome. This pattern is so strongly standardized that it persists in spite of real progress of treatments. Movies use disease, and other tragedies, as a dramatic device, and since drama is what we expect of the medium, should we be concerned that there is a gap between fiction and reality? Movies represent an essential step of educational process, but their potential has been fully exploited only in recent times. By watching movies on cancer, oncologists could become more conscious of problems they are already facing in the therapeutic setting: cancer and sexuality, the relationship between the ill person and the medical staff, side effects of therapies. Some films simply make us reflect upon the meaning of life and death. This is useful for the sharing of cancer care, from personal or familiar problems to issues of collective relevance.

Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Congresses as Topic; Death; Environmental Exposure; Female; Global Health; Humans; Italy; Life; Male; Middle Aged; Motion Pictures; Neoplasms; Nurse-Patient Relations; Patient Education as Topic; Physician-Patient Relations; Risk Factors; Sexuality

Hope is the foundation of the cancer patients' world and it is when the darkness is most profound that hope emerges as the true reality. Hope remains the patients' inner strength, a dynamism that grows more powerful even as the physical body weakens. We humans are always hoping for something and The Hope System addresses all levels of the entire cancer experience: physical, emotional, psychological and spiritual. By systematically learning how to recognize and honor patients' hopes, each of us can support him/her from first diagnosis to last breath in a way that is healing and positive for all. Utilizing this simple, powerful tool enables us to tap into the patient's ever changing reality, the role hope plays in one's life while confronting one's mortality, and be able to listen, hear and accompany them each step on their final life into death journey.

Topics: Adaptation, Psychological; Emotions; Hope; Humans; Life; Neoplasms; Pain

The aim of this research was to describe subjectively the lived experiences of students with mothers/fathers with cancer using a phenomenologic qualitative research method to explore life experiences of students about cancer and educational effects of it.. The research was carried out between April and October 2008 at Odemis Health School with students training in 2007-2008 in classes 1, 2, 3 and 4. The sample was 4 students with parents having a cancer.. Assessing the results, stressed fear of death, fear of loss, communication changeover in family, role changeover in family as experiences.. Subjects interpreted these in terms of future nursing education practice and expressed desires to provide more information to patients in their care. In this context, this research results contribute to professional nursing education.

Topics: Communication; Education, Nursing; Family Relations; Fathers; Humans; Information Dissemination; Learning; Life; Mothers; Neoplasms; Students, Nursing

Topics: Biochemistry; Career Mobility; Family; Humans; Life; Molecular Biology; Neoplasms; Women's Rights; Work

Although deemed vital to patient well-being, hope in persons who are terminally ill is often thought to be problematic, particularly when centered on cure. As part of a study on end-of-life decision-making, we asked 28 patients with cancer, believed to be within weeks of their death, to talk about hope. Responses were transcribed and discursively analyzed, with 3 versions of hope, each of which connected hope and life, identified--hope as essential to, and for, life; hope, life, death, and others; and, hope/s changing during (or in) life. Hope for cure was common. Rather than death-denying, patients' hope appeared life-affirming, functioning to value patients, their lives, and connections with others.

Topics: Aspirations, Psychological; Attitude; Attitude to Death; Death; Emotions; Female; Humans; Interviews as Topic; Life; Male; Neoplasms; Qualitative Research; Quality of Life; Terminally Ill

Topics: Animals; Antigens, Neoplasm; Humans; Immunologic Memory; Life; Monitoring, Immunologic; Neoplasms; Time Factors

We investigated the psychometric properties of a Dutch translation of the Personal Meaning Profile in a heterogeneous group of cancer patients. Our study resulted in a relatively short scale consisting of 39 of the 57 original items, divided into 5 factors, labeled 'relation with God'; 'dedication to life'; 'fairness of life'; 'goal-orientedness' and 'relations with other people', which can be summed to a total score of the experience of meaning in life. The internal consistency of the total scale as well as of its sub dimensions was high. The experience of meaning in life was positively related to feelings of psychological well-being and negatively to feelings of distress. Furthermore, the experience of meaning in life was also related to trait-like characteristics as personality. Future research can investigate its appropriateness for other populations than cancer patients, and if and how the experience of meaning in life eventually changes as a result of existential threats.

Topics: Adult; Aged; Aged, 80 and over; Anxiety; Attitude to Health; Culture; Depression; Female; Goals; Humans; Interpersonal Relations; Life; Life Change Events; Male; Middle Aged; Neoplasms; Netherlands; Personality; Religion; Self Concept; Social Adjustment; Surveys and Questionnaires

Impairments in physical and social functioning are often associated with distress for the cancer survivor. Impaired functioning may also lead individuals to question previously held beliefs about meaning in life. Meaning in life was hypothesized to mediate the relationship between functioning and distress.. Two studies were conducted. In the cross-sectional study (I), cancer survivors (N=420) were accrued via the Internet and completed measures of social and physical functioning, meaning and distress. In the longitudinal study (II), breast cancer survivors (N=167) completed measures of functioning at 18 months, meaning at 24 months and distress at 30 months post-diagnosis.. In Study I, meaning in life was a significant, partial mediator for both of the effects of physical and social functioning impairments on heightened distress. In Study II, significant indirect effects of functioning impairments on distress through meaning were replicated even when functioning and distress were measured 1 year apart. The relationship of social functioning and distress was fully mediated by meaning in life, whereas the relationship of physical functioning and distress was partially mediated by meaning.. The negative social and physical sequelae of cancer are associated with heightened distress, and this association appears to be accounted for, in part, by patients' loss of meaning in their lives.

Topics: Cross-Sectional Studies; Depression; Female; Humans; Life; Male; Middle Aged; Neoplasms; Severity of Illness Index; Social Behavior; Surveys and Questionnaires; Survival Rate; Survivors

The current scientific paradigm, based upon an erroneous assumption of linear biologic reality and simple cause and effect relationships, has outlived its usefulness. In order to begin to turn the voluminous data the reductive process provides us with daily into meaningful understanding of life, it is essential to integrate these data within a complex, multi-frequency temporo-spatial framework. This rhythmic chronobiology more accurately depicts the life process, as well as its evolutionary and ongoing vital interaction with the pulsating cosmic resonance structure. Examples of the kinds of thinking and experiments necessary to exploit this new paradigm are provided.

Topics: Antineoplastic Agents; Apoptosis; Chronobiology Phenomena; Drug Delivery Systems; Drug Therapy; Gene Expression; Humans; Life; Neoplasms; Observer Variation; Time

Topics: Animals; Diploidy; Humans; Life; Neoplasms; Sarcoma; Sarcoma, Yoshida

Topics: Humans; Life; Neoplasms; Probability; Radiology

Topics: Humans; Life; Neoplasms

Topics: Animals; Combined Modality Therapy; Life; Neoplasms; Neoplasms, Experimental; Podophyllin; Triethylenemelamine

Topics: HeLa Cells; Humans; Life; Microscopy; Neoplasms; Television; Viola

Topics: Humans; Incidence; Life; Neoplasms

Topics: Humans; Life; Neoplasms

Topics: Cell Count; Cell Nucleus; Humans; Interphase; Life; Microscopy; Neoplasms; Viola

Topics: Animals; Carcinogens; Electrodes; Hydrogen-Ion Concentration; Life; Neoplasms; Sulfhydryl Compounds

Topics: Cervix Uteri; Female; Humans; Life; Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms

Topics: Electrodes, Implanted; Hydrogen-Ion Concentration; Life; Neoplasms

Topics: Animals; Life; Neoplasm Transplantation; Neoplasms; Peritoneal Cavity; Rats

Topics: Humans; Insurance, Life; Life; Neoplasms

Topics: Cervix Uteri; Coitus; Female; Humans; Life; Neoplasms; Radium; Sexual Behavior; Uterine Cervical Neoplasms

Topics: Cell Count; Cells; Life; Microscopy; Neoplasms; Viola

Topics: Cell Count; Humans; Life; Microscopy; Microscopy, Ultraviolet; Neoplasms; Viola

Topics: Humans; Life; Life Expectancy; Neoplasms; Prognosis

Topics: Cells; Death; Humans; Life; Neoplasms

Topics: Humans; Inflammation; Life; Neoplasms

Topics: Aged; Aged, 80 and over; Energy Metabolism; Humans; Life; Neoplasms