endothelin-1 and Laryngeal-Neoplasms

endothelin-1 has been researched along with Laryngeal-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for endothelin-1 and Laryngeal-Neoplasms

ArticleYear
[Significance expression and relationships with endothelin-1, matrix metalloproteinase-9 in the laryngeal carcinoma].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2012, Volume: 26, Issue:6

    To evaluate the expression of endothelin-1(ET-1) and matrix metalloproteinase-9 (MMP-9) in laryngeal carcinoma and their correlations with clinical features.. The expression of ET-1 and MMP-9 was detected by immunohistochemical method in 58 specimens of laryngeal carcinoma, 28 specimens of polyps of vocal cord and 19 specimens of normal laryngeal tissues.. The expressions of ET-1, MMP-9 in laryngeal carcinoma were remarkably higher,compared to polyps of vocal cord and normal laryngeal tissues (P < 0.05). The expression of ET-1, MMP-9 was associated with clinical stage, T stage and lymph node metastasis. Expression levels of ET-land MMP-9 correlated significantly with each other (r(s) = 0.693, P < 0.05).. The expression of ET-1 and MMP-9 may be the vital indexes in laryngeal carcinoma.

    Topics: Adult; Aged; Carcinoma, Squamous Cell; Endothelin-1; Female; Humans; Laryngeal Neoplasms; Male; Matrix Metalloproteinase 9; Middle Aged; Neoplasm Staging

2012
[Expression of Endothelin-1 in laryngeal carcinoma].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2006, Volume: 20, Issue:24

    To study the expression and clinical significance of Endothelin-1 in laryngeal carcinoma.. Immunohistochemical (SP) method was used to detect the expression of Endothelin-1 in 30 cases of laryngeal carcinoma,20 cases of laryngeal benign lesions and 10 cases of. The relationship between the expression of Endothelin-1 and the clinic stage was analysed by SPSS12. 0 software. RESULT. The positive expression of Endothelin-1 in all three type tissues. There is a significant difference between the laryngeal carcinoma and the laryngeal benign lesions, the laryngeal carcinoma and the normal laryngeal mucous membrane, the laryngeal benign lesions and the normal laryngeal mucous membrane( P <0. 05). The highest expression of Endothelin-1 is in laryngeal carcinoma tissue. In laryngeal carcinoma tissue, the advanced clinical stage, the more higher expression of endothelin-1.. Positive expression of Endothelin-1 in laryngeal carcinoma tissue was highest in three tissue. It may be play an important role in carcinogenesis and progress of laryngeal carcinoma.

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Case-Control Studies; Endothelin-1; Humans; Laryngeal Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging

2006