endothelin-1 and Hemiplegia

To observe clinical therapeutic effect of sequential acupuncture method on apoplexy hemiplegia and to probe into the mechanism.. One hundred and forty-four cases of apoplexy hemiplegia were randomly divided into a treatment group treated with sequential acupuncture method and a control group treated with traditional acupuncture, 72 cases in each group. After treatment for 3 months, their clinical therapeutic effects were observed and plasma endothelin-1 (ET-1) and nitric oxide (NO) levels were detected.. The treatment group in the improvement of the nerve function-deficiency, total life ability and clinical overall effect, and the course of recovery, decreasing of ET-1 level and increasing of NO level was superior to the control group (P < 0.05, P < 0.01), the shorter the course, the better the therapeutic effect.. The sequential acupuncture method has an obvious therapeutic effect on apoplexy hemiplegia, and it can decrease plasma ET-1 level and increase NO level. It is an effective therapy for apoplexy hemiplegia.

Topics: Acupuncture Therapy; Adult; Endothelin-1; Female; Hemiplegia; Humans; Male; Middle Aged; Nitric Oxide; Stroke