endothelin-1 and Hand-Arm-Vibration-Syndrome

endothelin-1 has been researched along with Hand-Arm-Vibration-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for endothelin-1 and Hand-Arm-Vibration-Syndrome

ArticleYear
Analysis of long-term stored plasma samples for investigation into the pathophysiology of vibration-induced white finger: preliminary results.
    Industrial health, 2014, Volume: 52, Issue:6

    Blood samples were collected 25 yr ago from hand-arm vibration syndrome patients with vibration-induced white finge/VWF (VWF+ group) and without it (VWF- group), and healthy controls (n=12 in each group), and stored at -80 °C. The subjects provided venous blood twice: at baseline, and after cold exposure at 7 °C for 25 min. Blood specimens were analyzed for plasma endothelin-1 (ET-1) by an enzyme-linked immunosorbent assay. Baseline concentration of plasma ET-1 was found to be significantly larger in the VWF- group than the control group, whereas no such difference was observed for the VWF+ group. However, the %change was larger in the VWF+ group (107.73 ± 30.49%) than the other two groups, and more subjects in the VWF+ group showed the maximum increase in ET-1 than the other two groups. In conclusion, ET-1 appears to have a role in the pathophysiology of VWF.

    Topics: Biomarkers; Blood Specimen Collection; Case-Control Studies; Cold Temperature; Endothelin-1; Hand-Arm Vibration Syndrome; Healthy Volunteers; Humans; Middle Aged; Time Factors

2014