endosulfan has been researched along with Leukemia in 1 studies
Endosulfan: A polychlorinated compound used for controlling a variety of insects. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its mode of action involves repetitive nerve-discharges positively correlated to increase in temperature. This compound is extremely toxic to most fish. (From Comp Biochem Physiol (C) 1993 Jul;105(3):347-61)
endosulfan : A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We previously predicted that endosulfan might be associated with leukemia, but the role of endosulfan in leukemia cells has been unexplored." | 7.88 | Endosulfan causes the alterations of DNA damage response through ATM-p53 signaling pathway in human leukemia cells. ( Guo, Y; Liang, D; Sun, Y; Xu, D, 2018) |
| " We previously predicted that endosulfan might be associated with leukemia, but the role of endosulfan in leukemia cells has been unexplored." | 3.88 | Endosulfan causes the alterations of DNA damage response through ATM-p53 signaling pathway in human leukemia cells. ( Guo, Y; Liang, D; Sun, Y; Xu, D, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, D | 1 |
| Liang, D | 1 |
| Guo, Y | 1 |
| Sun, Y | 1 |
1 other study available for endosulfan and Leukemia
| Article | Year |
|---|---|
Endosulfan causes the alterations of DNA damage response through ATM-p53 signaling pathway in human leukemia cells.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caspase 3; Cell Line, Tumor; Cell Survival; Comet | 2018 |