Page last updated: 2024-10-26

endosulfan and Breast Cancer

endosulfan has been researched along with Breast Cancer in 10 studies

Endosulfan: A polychlorinated compound used for controlling a variety of insects. It is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its mode of action involves repetitive nerve-discharges positively correlated to increase in temperature. This compound is extremely toxic to most fish. (From Comp Biochem Physiol (C) 1993 Jul;105(3):347-61)
endosulfan : A cyclic sulfite ester that is 1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepine 3-oxide substituted by chloro groups at positions 6, 7, 8, 9, 10 and 10.

Research Excerpts

ExcerptRelevanceReference
"When curcumin and genistein were added together to MCF-7 cells, a synergistic effect resulting in a total inhibition of the induction of MCF-7 cells by the highly estrogenic activity of endosulfane/chlordane/DDT mixtures was noted."5.30Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. ( Goldin, B; Salamone, E; Verma, SP, 1997)
"The effects of simultaneous administration of some binary mixtures of seven natural and synthetic oestrogenic substances (17beta-estradiol, estrone, bisphenol A, butylbenzyl phthalate, endosulfan, methoxychlor and pentachlorophenol) on the cellular proliferation of human breast cancer MCF-7 cells in-vitro (a modified E-screen assay) have been measured."3.71Response of MCF-7 human breast cancer cells to some binary mixtures of oestrogenic compounds in-vitro. ( Ide, K; Ishida, M; Suzuki, T, 2001)
"The study includes a surgically treated breast cancer patient and a matching group of women with no sign of estrogenic-dependent disease."1.31Determination of endocrine-disrupting pesticides and polychlorinated biphenyls in human serum by GC-ECD and GC-MS-MS and evaluation of contributions to the uncertainty of the results. ( Garrido Frenich, A; Martínez Vidal, JL; Moreno Frías, M; Olea, N; Olea-Serrano, F, 2002)
"When curcumin and genistein were added together to MCF-7 cells, a synergistic effect resulting in a total inhibition of the induction of MCF-7 cells by the highly estrogenic activity of endosulfane/chlordane/DDT mixtures was noted."1.30Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. ( Goldin, B; Salamone, E; Verma, SP, 1997)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Sharma, S1
Malhotra, L1
Mukherjee, P1
Kaur, N1
Krishanlata, T1
Srikanth, CV1
Mishra, V1
Banerjee, BD1
Ethayathulla, AS1
Sharma, RS1
Kalinina, TS1
Kononchuk, VV1
Gulyaeva, LF1
Cossette, LJ1
Gaumond, I1
Martinoli, MG1
Bonefeld-Jorgensen, EC1
Grünfeld, HT1
Gjermandsen, IM1
Soto, AM1
Chung, KL1
Sonnenschein, C1
Verma, SP1
Salamone, E1
Goldin, B1
Arcaro, KF1
Vakharia, DD1
Yang, Y1
Gierthy, JF1
Coumoul, X1
Diry, M1
Robillot, C1
Barouki, R1
Suzuki, T1
Ide, K1
Ishida, M1
Martínez Vidal, JL1
Moreno Frías, M1
Garrido Frenich, A1
Olea-Serrano, F1
Olea, N1

Other Studies

10 other studies available for endosulfan and Breast Cancer

ArticleYear
Putative interactions between transthyretin and endosulfan II and its relevance in breast cancer.
    International journal of biological macromolecules, 2023, Apr-30, Volume: 235

    Topics: Breast Neoplasms; Case-Control Studies; Endosulfan; Female; Humans; Hydrocarbons, Chlorinated; Molec

2023
Expression of estrogen-, progesterone-, and androgen-responsive genes in MCF-7 and MDA-MB-231 cells treated with o,p'-DDT, p,p'-DDT, or endosulfan.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:6

    Topics: Androgens; Breast Neoplasms; DDT; Endocrine Disruptors; Endosulfan; Estrogens; Female; Gene Expressi

2021
Combined effect of xenoestrogens and growth factors in two estrogen-responsive cell lines.
    Endocrine, 2002, Volume: 18, Issue:3

    Topics: Animals; Breast Neoplasms; Cell Division; Cell Line; Chlordan; Drug Synergism; Endosulfan; Epidermal

2002
Effect of pesticides on estrogen receptor transactivation in vitro: a comparison of stable transfected MVLN and transient transfected MCF-7 cells.
    Molecular and cellular endocrinology, 2005, Dec-01, Volume: 244, Issue:1-2

    Topics: Biological Assay; Breast Neoplasms; Carbamates; Cell Line, Tumor; Dose-Response Relationship, Drug;

2005
The pesticides endosulfan, toxaphene, and dieldrin have estrogenic effects on human estrogen-sensitive cells.
    Environmental health perspectives, 1994, Volume: 102, Issue:4

    Topics: Biological Assay; Breast Neoplasms; Cell Division; Dieldrin; Drug Synergism; Endosulfan; Female; Hum

1994
Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides.
    Biochemical and biophysical research communications, 1997, Apr-28, Volume: 233, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Division; Chlordan; Curcumin; DDT; Dieldri

1997
Lack of synergy by mixtures of weakly estrogenic hydroxylated polychlorinated biphenyls and pesticides.
    Environmental health perspectives, 1998, Volume: 106 Suppl 4

    Topics: Adenocarcinoma; Binding, Competitive; Breast Neoplasms; Dieldrin; Dose-Response Relationship, Drug;

1998
Differential regulation of cytochrome P450 1A1 and 1B1 by a combination of dioxin and pesticides in the breast tumor cell line MCF-7.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; C

2001
Response of MCF-7 human breast cancer cells to some binary mixtures of oestrogenic compounds in-vitro.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:11

    Topics: Benzhydryl Compounds; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Drug Intera

2001
Determination of endocrine-disrupting pesticides and polychlorinated biphenyls in human serum by GC-ECD and GC-MS-MS and evaluation of contributions to the uncertainty of the results.
    Analytical and bioanalytical chemistry, 2002, Volume: 372, Issue:7-8

    Topics: Breast Neoplasms; Chromatography, Gas; Chromatography, High Pressure Liquid; Electrochemistry; Endos

2002