endomorphin-2 and Brain-Neoplasms

endomorphin-2 has been researched along with Brain-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for endomorphin-2 and Brain-Neoplasms

Article	Year
Ca2+ channel inhibition by endomorphins via the cloned mu-opioid receptor expressed in NG108-15 cells. European journal of pharmacology, 1997, Dec-11, Volume: 340, Issue:2-3 Endomorphin-1 and -2, recently isolated endogenous peptides specific for the mu-opioid receptor, inhibited Ca2+ channel currents with EC50 of 6 and 9 nM, respectively, in NG108-15 cells transformed to express the cloned rat mu-opioid receptor. On the other hand, they elicited no response in nontransfected NG108-15 cells. It is concluded that endomorphin-1 and -2 induce Ca2+ channel inhibition by selectively activating the mu-opioid receptor. Topics: Analgesics, Opioid; Animals; Brain Neoplasms; Calcium Channel Blockers; Glioma; Neuroblastoma; Oligopeptides; Rats; Receptors, Opioid, mu; Recombinant Proteins; Tumor Cells, Cultured	1997

Article

Year

Ca2+ channel inhibition by endomorphins via the cloned mu-opioid receptor expressed in NG108-15 cells.

European journal of pharmacology, 1997, Dec-11, Volume: 340, Issue:2-3

Endomorphin-1 and -2, recently isolated endogenous peptides specific for the mu-opioid receptor, inhibited Ca2+ channel currents with EC50 of 6 and 9 nM, respectively, in NG108-15 cells transformed to express the cloned rat mu-opioid receptor. On the other hand, they elicited no response in nontransfected NG108-15 cells. It is concluded that endomorphin-1 and -2 induce Ca2+ channel inhibition by selectively activating the mu-opioid receptor.

Topics: Analgesics, Opioid; Animals; Brain Neoplasms; Calcium Channel Blockers; Glioma; Neuroblastoma; Oligopeptides; Rats; Receptors, Opioid, mu; Recombinant Proteins; Tumor Cells, Cultured

1997