enalapril and Primate-Diseases

This report describes the diagnosis and treatment of pulmonary arterial hypertension (PAH) in an adult male captive chimpanzee. Although cardiovascular disease in general is common in human and great apes, diagnosis and treatment of PAH in nonhuman primates are uncommon. In the case we present, the adult chimpanzee was diagnosed with an arrhythmia during an annual physical examination and later with PAH during a scheduled cardiovascular evaluation. PAH can either be primary or secondary and can lead to right ventricular overload and heart failure. This description is the first case study of pulmonary arterial hypertension in a great ape species.

Topics: Animals; Antihypertensive Agents; Aspirin; Atrial Fibrillation; Cardiotonic Agents; Digoxin; Diuretics; Enalapril; Furosemide; Hypertension, Pulmonary; Liver; Lung; Male; Myocardium; Pan troglodytes; Platelet Aggregation Inhibitors; Primate Diseases