enalapril and Hodgkin-Disease

enalapril has been researched along with Hodgkin-Disease* in 1 studies

Trials

1 trial(s) available for enalapril and Hodgkin-Disease

ArticleYear
[Angiotensin converting enzyme inhibitor enalapril in the treatment of endomyocardial fibrosis in patients with lymphogranulomatosis subjected to radio- and chemotherapy].
    Kardiologiia, 2002, Volume: 42, Issue:11

    Echocardiography was used in the study of 40 patients with stage IIA-IVB lymphogranulomatosis. In 2-6 years before the study all patients had been treated with combination radio- (36-44 Gy) and chemotherapy. Echocardiography revealed endomyocardial fibrosis and signs of cardiac remodeling (reduced left ventricular dimensions and volumes, decreased myocardial mass and impaired diastolic function). The patients were divided into 2 groups. Patients of group 1 were given enalapril (5-10 mg/day), of group 2 - potassium and magnesium aspartate and inosine. In 2 months 68% of patients in group 1 demonstrated improvement of structural and functional state of the heart, no such changes occurred in group 2.

    Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Enalapril; Endomyocardial Fibrosis; Female; Hodgkin Disease; Humans; Male; Middle Aged; Radiotherapy

2002