enalapril and Ascites

enalapril has been researched along with Ascites* in 2 studies

Other Studies

2 other study(ies) available for enalapril and Ascites

Article	Year
ACE inhibitors in the management of haemodialysis ascites. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:11 Topics: Ascites; Enalapril; Female; Humans; Kidney Failure, Chronic; Middle Aged; Renal Dialysis	1994
Renal and hormonal responses to repeated treatment with enalapril in non-azotemic cirrhosis with ascites. Journal of hepatology, 1994, Volume: 20, Issue:2 Since a single dose of the angiotensin-converting enzyme inhibitor enalapril was shown to cause natriuresis in cirrhosis in a previous study, we investigated whether repeated doses of this substance would sustain a favorable renal effect in cirrhosis. Ten milligrams of enalapril maleate were administered once a day for 8 days to ten patients with non-azotemic cirrhosis and ascites. Enalapril reduced blood pressure significantly at 4 to 12 h (systolic blood pressure) and 2, 6, and 8 h (diastolic blood pressure) on day 2, compared to pretreatment (day 0) values, but this depressor effect decreased on day 8. No change in heart rate could be detected. Enalapril significantly suppressed serum angiotensin-converting enzyme activity and plasma aldosterone concentration (p < 0.001 to 0.01), which were elevated prior to treatment, with pretreatment values of 25.8 +/- 1.8 IU/l for serum angiotensin-converting enzyme activity and 241 +/- 67 pg/ml for plasma aldosterone concentration. This drug caused a 12 to 24% increase (p < 0.05 to 0.01) in mean daily urinary volume and a 40 to 54% increase (p < 0.001 to 0.01) in mean daily urinary sodium excretion from the respective pretreatment baselines during the 8-day period. Creatinine clearance was improved (p < 0.05) by the treatment, with mean improvement values from 24 to 34% above the pretreatment value of 47.4 +/- 4.3 ml/min.(ABSTRACT TRUNCATED AT 250 WORDS) Topics: Aged; Ascites; Blood Pressure; Creatinine; Enalapril; Female; Heart Rate; Humans; Kidney; Liver Cirrhosis; Male; Middle Aged; Natriuresis; Peptidyl-Dipeptidase A	1994

Article

Year

ACE inhibitors in the management of haemodialysis ascites.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:11

Topics: Ascites; Enalapril; Female; Humans; Kidney Failure, Chronic; Middle Aged; Renal Dialysis

1994

Renal and hormonal responses to repeated treatment with enalapril in non-azotemic cirrhosis with ascites.

Journal of hepatology, 1994, Volume: 20, Issue:2

Since a single dose of the angiotensin-converting enzyme inhibitor enalapril was shown to cause natriuresis in cirrhosis in a previous study, we investigated whether repeated doses of this substance would sustain a favorable renal effect in cirrhosis. Ten milligrams of enalapril maleate were administered once a day for 8 days to ten patients with non-azotemic cirrhosis and ascites. Enalapril reduced blood pressure significantly at 4 to 12 h (systolic blood pressure) and 2, 6, and 8 h (diastolic blood pressure) on day 2, compared to pretreatment (day 0) values, but this depressor effect decreased on day 8. No change in heart rate could be detected. Enalapril significantly suppressed serum angiotensin-converting enzyme activity and plasma aldosterone concentration (p < 0.001 to 0.01), which were elevated prior to treatment, with pretreatment values of 25.8 +/- 1.8 IU/l for serum angiotensin-converting enzyme activity and 241 +/- 67 pg/ml for plasma aldosterone concentration. This drug caused a 12 to 24% increase (p < 0.05 to 0.01) in mean daily urinary volume and a 40 to 54% increase (p < 0.001 to 0.01) in mean daily urinary sodium excretion from the respective pretreatment baselines during the 8-day period. Creatinine clearance was improved (p < 0.05) by the treatment, with mean improvement values from 24 to 34% above the pretreatment value of 47.4 +/- 4.3 ml/min.(ABSTRACT TRUNCATED AT 250 WORDS)

Topics: Aged; Ascites; Blood Pressure; Creatinine; Enalapril; Female; Heart Rate; Humans; Kidney; Liver Cirrhosis; Male; Middle Aged; Natriuresis; Peptidyl-Dipeptidase A

1994