Page last updated: 2024-10-26

emorfazone and Edema

emorfazone has been researched along with Edema in 4 studies

emorfazone: structure

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"Effects of 4-ethoxy-3-methyl-5-morpholino-3(2H)-pyridazinone (emorfazone, M 73101) on thermic edema in rats were investigated, and following results were obtained: Oral administration of emorfazone (100 and 200 mg/kg) significantly inhibited the edema formation resulting from immersing the rat paws in a water bath maintained at 46."7.66Studies on mechanisms of action of emorfazone. Effects on the release of bradykinin-like substance in thermic edema of rat paws. ( Sato, M; Yamaguchi, A, 1982)
"Effects of 4-ethoxy-3-methyl-5-morpholino-3(2H)-pyridazinone (emorfazone, M 73101) on thermic edema in rats were investigated, and following results were obtained: Oral administration of emorfazone (100 and 200 mg/kg) significantly inhibited the edema formation resulting from immersing the rat paws in a water bath maintained at 46."3.66Studies on mechanisms of action of emorfazone. Effects on the release of bradykinin-like substance in thermic edema of rat paws. ( Sato, M; Yamaguchi, A, 1982)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takaya, M1
Sato, M3
Terashima, K1
Tanizawa, H2
Maki, Y1
Yamaguchi, A1
Ishizuka, Y1
Seki, K1
Fukuda, T1
Yuizono, T1
Yonehara, N1
Shibutani, T1
Inoki, R1

Other Studies

4 other studies available for emorfazone and Edema

ArticleYear
A new nonsteroidal analgesic-antiinflammatory agent. Synthesis and activity of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone and related compounds.
    Journal of medicinal chemistry, 1979, Volume: 22, Issue:1

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Edema; Lethal Dose 50; Male

1979
Studies on mechanisms of action of emorfazone. Effects on the release of bradykinin-like substance in thermic edema of rat paws.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Bradykinin; Burns; Edema; Kininogens; Lysine Carboxypeptidase; Py

1982
[Pharmacological studies of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (M73101). (2). Anti-inflammatory activity (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:2

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Body Temperature; Capilla

1979
Contribution of substance P to heat-induced edema in rat paw.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: Animals; Bradykinin; Capsaicin; Denervation; Edema; Histamine; Hot Temperature; Male; Pyridazines; R

1987