Page last updated: 2024-10-26

emodin and Ureteral Obstruction

emodin has been researched along with Ureteral Obstruction in 3 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Ureteral Obstruction: Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.

Research Excerpts

ExcerptRelevanceReference
"In order to enhance renal fibrosis therapy of emodin, an innovative combination therapy based on deoxycholic acid-chitosan coated liposomes (DCS-Lips) and in situ colonic gel (IGE) was developed."8.12Deoxycholic acid-chitosan coated liposomes combined with in situ colonic gel enhances renal fibrosis therapy of emodin. ( Fan, X; Hou, Y; Piao, JG; Sun, J; Wei, Y; Xu, Z; Yao, W; Zhang, K; Zhang, Q; Zhu, L, 2022)
" Moreover, a unilateral ureteral obstruction-induced mouse model of renal fibrosis was established for investigating the antifibrotic effect of emodin in combination with HGF in vivo."7.96Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ-Smad Signaling Pathway. ( Chen, M; Deng, L; Hu, Y; Li, J; Liu, Y; Yang, F; Zhong, W, 2020)
"In order to enhance renal fibrosis therapy of emodin, an innovative combination therapy based on deoxycholic acid-chitosan coated liposomes (DCS-Lips) and in situ colonic gel (IGE) was developed."4.12Deoxycholic acid-chitosan coated liposomes combined with in situ colonic gel enhances renal fibrosis therapy of emodin. ( Fan, X; Hou, Y; Piao, JG; Sun, J; Wei, Y; Xu, Z; Yao, W; Zhang, K; Zhang, Q; Zhu, L, 2022)
" Moreover, a unilateral ureteral obstruction-induced mouse model of renal fibrosis was established for investigating the antifibrotic effect of emodin in combination with HGF in vivo."3.96Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ-Smad Signaling Pathway. ( Chen, M; Deng, L; Hu, Y; Li, J; Liu, Y; Yang, F; Zhong, W, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Xu, Z1
Hou, Y1
Sun, J1
Zhu, L1
Zhang, Q1
Yao, W1
Fan, X1
Zhang, K1
Piao, JG1
Wei, Y1
Yang, F2
Deng, L1
Li, J1
Chen, M1
Liu, Y1
Hu, Y1
Zhong, W1
Xu, L1
Gao, J1
Huang, D1
Lin, P1
Yao, D1
Zhang, Y1
Yang, X1
Wu, M1
Ye, C1

Other Studies

3 other studies available for emodin and Ureteral Obstruction

ArticleYear
Deoxycholic acid-chitosan coated liposomes combined with in situ colonic gel enhances renal fibrosis therapy of emodin.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 101

    Topics: Animals; Caco-2 Cells; Chitosan; Deoxycholic Acid; DNA, Ribosomal; Dysbiosis; Emodin; Female; Fibros

2022
Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ-Smad Signaling Pathway.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Emodin; Fibrosis

2020
Emodin ameliorates tubulointerstitial fibrosis in obstructed kidneys by inhibiting EZH2.
    Biochemical and biophysical research communications, 2021, 01-01, Volume: 534

    Topics: Animals; Connective Tissue Growth Factor; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Enh

2021