Page last updated: 2024-10-26

emodin and Skin Neoplasms

emodin has been researched along with Skin Neoplasms in 8 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Skin Neoplasms: Tumors or cancer of the SKIN.

Research Excerpts

ExcerptRelevanceReference
"Emodin is a Chinese herb-derived compound that exhibits a variety of pharmacological benefits."1.51Anticancer activity of emodin is associated with downregulation of CD155. ( Fan, D; Fang, L; Iwanowycz, S; Wang, J; Wang, Y; Yin, S; Zhao, F, 2019)
"Melanoma is the most malignant type of skin cancer."1.43Upregulation of miR-124 by physcion 8-O-β-glucopyranoside inhibits proliferation and invasion of malignant melanoma cells via repressing RLIP76. ( Han, Y; Xu, L; Zhang, D, 2016)
"Aloe emodin has been reported to be nontoxic for normal cells but to possess specific toxicity for neuroectodermal tumor cells."1.31The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line. ( Avigad, S; Beery, E; Fenig, E; Nordenberg, J; Wasserman, L, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's2 (25.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Nowak-Perlak, M1
Bromke, MA1
Ziółkowski, P1
Woźniak, M1
Cao, X1
Deng, T1
Zhu, Q1
Wang, J2
Shi, W1
Liu, Q1
Yu, Q1
Deng, W1
Yu, J1
Wang, Q1
Xiao, G1
Xu, X1
Fang, L1
Zhao, F1
Iwanowycz, S1
Yin, S1
Wang, Y1
Fan, D1
Zhang, D1
Han, Y1
Xu, L1
Badgwell, DB1
Walker, CM1
Baker, WT1
Strickland, FM2
Muller, HK1
Stephens, LC1
Bucana, CD1
Donawho, CK1
Sun, Y1
Pelley, RP1
Wasserman, L1
Avigad, S1
Beery, E1
Nordenberg, J1
Fenig, E1
Koyama, J1
Morita, I1
Tagahara, K1
Nobukuni, Y1
Mukainaka, T1
Kuchide, M1
Tokuda, H1
Nishino, H1

Other Studies

8 other studies available for emodin and Skin Neoplasms

ArticleYear
The Comparison of the Efficiency of Emodin and Aloe-Emodin in Photodynamic Therapy.
    International journal of molecular sciences, 2022, Jun-03, Volume: 23, Issue:11

    Topics: Aloe; Anthraquinones; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Emodin; Humans; Melanom

2022
Photothermal Therapy Mediated Hybrid Membrane Derived Nano-formulation for Enhanced Cancer Therapy.
    AAPS PharmSciTech, 2023, Jun-28, Volume: 24, Issue:6

    Topics: Emodin; Glycyrrhizic Acid; Humans; Melanoma; Photothermal Therapy; Reactive Oxygen Species; Skin Neo

2023
Anticancer activity of emodin is associated with downregulation of CD155.
    International immunopharmacology, 2019, Volume: 75

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation

2019
Upregulation of miR-124 by physcion 8-O-β-glucopyranoside inhibits proliferation and invasion of malignant melanoma cells via repressing RLIP76.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultu

2016
Ethanol and aloe emodin alter the p53 mutational spectrum in ultraviolet radiation-induced murine skin tumors.
    Molecular carcinogenesis, 2004, Volume: 39, Issue:3

    Topics: Animals; Anthraquinones; Base Sequence; DNA Primers; Emodin; Ethanol; Female; Genes, p53; Mice; Mice

2004
Induction of primary cutaneous melanomas in C3H mice by combined treatment with ultraviolet radiation, ethanol and aloe emodin.
    Photochemistry and photobiology, 2000, Volume: 72, Issue:3

    Topics: Animals; Anthraquinones; Carcinogens; Emodin; Ethanol; Female; Melanoma; Mice; Mice, Inbred C3H; Neo

2000
The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line.
    The American Journal of dermatopathology, 2002, Volume: 24, Issue:1

    Topics: Aged; Anthraquinones; Antineoplastic Agents; Biomarkers, Tumor; Butyrates; Carcinoma, Merkel Cell; C

2002
Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis.
    Cancer letters, 2002, Aug-28, Volume: 182, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthraquinones; Anticarcinogenic Agents; Cassia; Emodin;

2002