emodin has been researched along with Renal Insufficiency, Chronic in 6 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin is an active element from the root of curcuma longa with extensive beneficial properties, including antioxidant, anti-inflammatory activity, and inhibitory effects on cell apoptosis." | 2.72 | Herbal antioxidants in dialysis patients: a review of potential mechanisms and medical implications. ( Alirezaei, A; Asgharpour, M, 2021) |
| "The study aimed to explore the pharmacokinetic and pharmacodynamic alterations of the active components of Shenkang injection (i." | 1.91 | Pharmacokinetic-pharmacodynamic modeling of the active components of Shenkang injection in rats with chronic renal failure and its protective effect on damaged renal cells. ( Fu, Z; Jia, Q; Sun, Z; Wang, X; Xia, J; Xue, L; Zhang, L; Zhou, L, 2023) |
| "Emodin was administered via colonic irrigation at 5ml (1mg/day) for four weeks." | 1.43 | Emodin via colonic irrigation modulates gut microbiota and reduces uremic toxins in rats with chronic kidney disease. ( Chen, C; Dai, Z; Hua, Z; Li, D; Liu, X; Lu, F; Lu, Z; Qu, P; Qu, Y; Zeng, YQ; Zou, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 4 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Yan, YM | 1 |
| Wei, W | 1 |
| Luo, J | 1 |
| Zhang, LS | 1 |
| Zhou, XJ | 1 |
| Wang, PC | 1 |
| Yang, YX | 1 |
| Cheng, YX | 1 |
| Zhou, L | 2 |
| Wang, X | 2 |
| Xia, J | 2 |
| Zhang, L | 1 |
| Xue, L | 2 |
| Jia, Q | 1 |
| Fu, Z | 1 |
| Sun, Z | 2 |
| Bao, X | 1 |
| Xu, Z | 1 |
| Dong, P | 1 |
| Xu, L | 1 |
| Gao, J | 1 |
| Huang, D | 1 |
| Lin, P | 1 |
| Yao, D | 1 |
| Yang, F | 1 |
| Zhang, Y | 1 |
| Yang, X | 1 |
| Wu, M | 1 |
| Ye, C | 1 |
| Asgharpour, M | 1 |
| Alirezaei, A | 1 |
| Zeng, YQ | 1 |
| Dai, Z | 1 |
| Lu, F | 1 |
| Lu, Z | 1 |
| Liu, X | 1 |
| Chen, C | 1 |
| Qu, P | 1 |
| Li, D | 1 |
| Hua, Z | 1 |
| Qu, Y | 1 |
| Zou, C | 1 |
1 review available for emodin and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Herbal antioxidants in dialysis patients: a review of potential mechanisms and medical implications.
Topics: Antioxidants; Cardiovascular Diseases; Curcumin; Emodin; Humans; Inflammation; Oxidative Stress; Pla | 2021 |
5 other studies available for emodin and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy.
Topics: Anthraquinones; Aspergillus fumigatus; Cell Survival; Diabetic Nephropathies; Dose-Response Relation | 2013 |
Pharmacokinetic-pharmacodynamic modeling of the active components of Shenkang injection in rats with chronic renal failure and its protective effect on damaged renal cells.
Topics: Animals; Drugs, Chinese Herbal; Emodin; Fibrosis; Kidney; Kidney Failure, Chronic; Rats; Rats, Sprag | 2023 |
Study on the mechanism of Shenkang injection in the treatment of chronic renal failure based on the strategy of "Network pharmacology-Molecular docking-Key target validation".
Topics: Animals; Drugs, Chinese Herbal; Emodin; Kidney Failure, Chronic; Molecular Docking Simulation; Netwo | 2023 |
Emodin ameliorates tubulointerstitial fibrosis in obstructed kidneys by inhibiting EZH2.
Topics: Animals; Connective Tissue Growth Factor; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Enh | 2021 |
Emodin via colonic irrigation modulates gut microbiota and reduces uremic toxins in rats with chronic kidney disease.
Topics: Animals; Emodin; Gastrointestinal Microbiome; Indican; Male; Microbiota; Random Allocation; Rats; Ra | 2016 |