emodin has been researched along with Osteosarcoma in 2 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emodin induces death of human osteosarcoma cells by initiating ROS-dependent mitochondria-induced and ROS-independent ER stress-induced apoptosis." | 7.81 | Emodin induces apoptosis of human osteosarcoma cells via mitochondria- and endoplasmic reticulum stress-related pathways. ( Wu, D; Wu, X; Xu, H; Ying, J, 2015) |
| "Emodin induces death of human osteosarcoma cells by initiating ROS-dependent mitochondria-induced and ROS-independent ER stress-induced apoptosis." | 3.81 | Emodin induces apoptosis of human osteosarcoma cells via mitochondria- and endoplasmic reticulum stress-related pathways. ( Wu, D; Wu, X; Xu, H; Ying, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qu, W | 1 |
| Wang, Y | 1 |
| Wu, Q | 1 |
| Hao, D | 1 |
| Li, D | 1 |
| Ying, J | 1 |
| Xu, H | 1 |
| Wu, D | 1 |
| Wu, X | 1 |
2 other studies available for emodin and Osteosarcoma
| Article | Year |
|---|---|
Emodin Impairs Radioresistance of Human Osteosarcoma Cells by Suppressing Sonic Hedgehog Signaling.
Topics: Cell Line, Tumor; Emodin; Hedgehog Proteins; Humans; Osteosarcoma; Radiation Tolerance; Signal Trans | 2017 |
Emodin induces apoptosis of human osteosarcoma cells via mitochondria- and endoplasmic reticulum stress-related pathways.
Topics: Apoptosis; Bone Neoplasms; Caspase 3; Cell Line, Tumor; Dose-Response Relationship, Drug; Emodin; En | 2015 |