emodin has been researched along with Neuralgia in 6 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emodin treatment significantly reduced lipid peroxidation and NO levels while restoring the GST, GSH and catalase." | 5.91 | Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. ( Ali, F; Alvi, AM; Badshah, I; Bungau, S; Hassan, SSU; Imran, M; Kandeel, M; Minhas, AM; Qazi, NG, 2023) |
| "Emodin treatment evoked the expression alteration of 402 proteins (153 up-regulated and 249 down-regulated) in the CCI models, which were primarily involved in PI3K/AKT signaling pathway, gamma-aminobutyric acid (GABA) receptor signaling, complement and coagulation cascades, cGMP/PKG signaling pathway, MAPK signaling pathway, and calcium signaling pathway." | 1.91 | Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma-aminobutyric acid (GABA)-ergic pathway and PI3K/AKT/NF-κB pathway. ( Chen, P; Gong, Q; Huang, NY; Liu, C; Luo, RX; Pang, B; Wang, C; Wang, L; Ye, ZJ, 2023) |
| "Emodin treatment significantly reduced lipid peroxidation and NO levels while restoring the GST, GSH and catalase." | 1.91 | Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. ( Ali, F; Alvi, AM; Badshah, I; Bungau, S; Hassan, SSU; Imran, M; Kandeel, M; Minhas, AM; Qazi, NG, 2023) |
| "Emodin was effective in relieving neuropathic pain, which is linked to inhibition inflammatory response, increasing the proportion of beneficial bacteria and beneficial metabolites." | 1.91 | Integration of microbiota and metabolomics reveals the analgesic mechanisms of emodin against neuropathic pain. ( Ali Khan, A; Chen, L; Chen, P; Hu, Y; Huang, S; Lu, D; Song, C; Wang, C; Wu, L; Zhou, R, 2023) |
| "Emodin is a natural anthraquinone in rhubarb." | 1.37 | Effect of emodin on neuropathic pain transmission mediated by P2X2/3 receptor of primary sensory neurons. ( Deng, L; Gao, Y; Kong, F; Li, G; Liang, S; Liu, H; Liu, J; Liu, S; Wu, R; Xie, J; Xu, C; Zhu, G, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 5 (83.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, P | 3 |
| Wang, C | 3 |
| Luo, RX | 2 |
| Wu, ZB | 1 |
| Xia, DB | 1 |
| Yang, HY | 1 |
| Wu, J | 1 |
| Lu, H | 1 |
| Cheng, ML | 1 |
| Wang, BH | 1 |
| Zhu, HL | 1 |
| Liu, L | 1 |
| Xie, M | 1 |
| Huang, NY | 1 |
| Pang, B | 1 |
| Ye, ZJ | 1 |
| Liu, C | 1 |
| Gong, Q | 1 |
| Wang, L | 1 |
| Badshah, I | 1 |
| Qazi, NG | 1 |
| Ali, F | 1 |
| Minhas, AM | 1 |
| Alvi, AM | 1 |
| Kandeel, M | 1 |
| Imran, M | 1 |
| Hassan, SSU | 1 |
| Bungau, S | 1 |
| Wu, L | 1 |
| Zhou, R | 1 |
| Song, C | 1 |
| Huang, S | 1 |
| Ali Khan, A | 1 |
| Lu, D | 1 |
| Hu, Y | 1 |
| Chen, L | 1 |
| Gao, Y | 1 |
| Liu, H | 1 |
| Deng, L | 1 |
| Zhu, G | 1 |
| Xu, C | 1 |
| Li, G | 2 |
| Liu, S | 1 |
| Xie, J | 1 |
| Liu, J | 1 |
| Kong, F | 1 |
| Wu, R | 1 |
| Liang, S | 1 |
6 other studies available for emodin and Neuralgia
| Article | Year |
|---|---|
[Mechanism of emodin in relieving neuropathic pain by regulating serum metabolism].
Topics: Analgesics; Animals; Arginine; Emodin; Neuralgia; Rats; Rats, Sprague-Dawley; Sphingolipids | 2022 |
Emodin suppresses oxaliplatin-induced neuropathic pain by inhibiting COX2/NF-κB mediated spinal inflammation.
Topics: Animals; Cyclooxygenase 2; Emodin; Inflammation; Neuralgia; NF-kappa B; Oxaliplatin; Quality of Life | 2023 |
Proteomic and metabolomic approaches elucidate the molecular mechanism of emodin against neuropathic pain through modulating the gamma-aminobutyric acid (GABA)-ergic pathway and PI3K/AKT/NF-κB pathway.
Topics: Animals; Emodin; gamma-Aminobutyric Acid; Neuralgia; NF-kappa B; Phosphatidylinositol 3-Kinases; Pro | 2023 |
Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway.
Topics: Animals; Constriction; Emodin; Hyperalgesia; Inflammation; Neuralgia; Peroxisome Proliferator-Activa | 2023 |
Integration of microbiota and metabolomics reveals the analgesic mechanisms of emodin against neuropathic pain.
Topics: Analgesics; Animals; DNA, Ribosomal; Emodin; Male; Microbiota; Neuralgia; Rats; Rats, Sprague-Dawley | 2023 |
Effect of emodin on neuropathic pain transmission mediated by P2X2/3 receptor of primary sensory neurons.
Topics: Analgesics; Animals; Emodin; Ganglia, Spinal; Male; Neuralgia; Pain Measurement; Protein Kinase Inhi | 2011 |