emodin has been researched along with Neoplasm Metastasis in 11 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aloe-emodin (AE) has been found to be an anti-tumor agent in many studies, and has also been demonstrated as a photosensitizer, in the recent years." | 5.43 | Exploring a Novel Target Treatment on Breast Cancer: Aloe-emodin Mediated Photodynamic Therapy Induced Cell Apoptosis and Inhibited Cell Metastasis. ( Bai, DQ; Chen, Q; Li, KT; Tian, S; Yu, LH; Yu, TH; Zhu, J, 2016) |
| "Treatment of HER-2-overexpressing breast cancer cells with AE reduced tumor initiation, cell migration, and cell invasion." | 5.43 | Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells. ( Ho, CT; Hung, CM; Kao, JY; Lin, YC; Ma, JW; Way, TD, 2016) |
| "Advanced breast cancer is prone to metastasis, and there is currently no drug to cure metastatic breast cancer." | 2.72 | P2X7 receptor: a critical regulator and potential target for breast cancer. ( Li, Q; Peng, X; Song, W; Zhao, R; Zhu, X, 2021) |
| "Emodin is an active anthraquinone derivative isolated from Rheum palmatum, with anticancer properties that have been reported to inhibit lung metastasis in a nude mouse xenograft model." | 1.48 | Emodin inhibits epithelial‑mesenchymal transition and metastasis of triple negative breast cancer via antagonism of CC‑chemokine ligand 5 secreted from adipocytes. ( Liu, S; Qin, Y; Song, X; Sun, Z; Wang, Y; Yang, J; Yu, K; Zhang, S; Zhou, X, 2018) |
| "Aloe-emodin (AE) has been found to be an anti-tumor agent in many studies, and has also been demonstrated as a photosensitizer, in the recent years." | 1.43 | Exploring a Novel Target Treatment on Breast Cancer: Aloe-emodin Mediated Photodynamic Therapy Induced Cell Apoptosis and Inhibited Cell Metastasis. ( Bai, DQ; Chen, Q; Li, KT; Tian, S; Yu, LH; Yu, TH; Zhu, J, 2016) |
| "Human colorectal cancer cell line SW620 was tested." | 1.43 | Physcion inhibits the metastatic potential of human colorectal cancer SW620 cells in vitro by suppressing the transcription factor SOX2. ( Chen, XH; Gao, H; Han, YT; Wang, CB; Ye, JL, 2016) |
| "Treatment of HER-2-overexpressing breast cancer cells with AE reduced tumor initiation, cell migration, and cell invasion." | 1.43 | Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells. ( Ho, CT; Hung, CM; Kao, JY; Lin, YC; Ma, JW; Way, TD, 2016) |
| "To investigate the anti-metastasis effect of emodin on the pancreatic cancer in vitro and in vivo." | 1.37 | [Experimental study on anti-metastasis effect of emodin on human pancreatic cancer]. ( Huang, L; Lin, S; Liu, A; Sha, L; Shen, Y; Tang, X, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (81.82) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, X | 1 |
| Li, Q | 1 |
| Song, W | 1 |
| Peng, X | 1 |
| Zhao, R | 1 |
| Song, X | 1 |
| Zhou, X | 1 |
| Qin, Y | 1 |
| Yang, J | 1 |
| Wang, Y | 2 |
| Sun, Z | 1 |
| Yu, K | 1 |
| Zhang, S | 1 |
| Liu, S | 1 |
| Jelassi, B | 1 |
| Anchelin, M | 1 |
| Chamouton, J | 1 |
| Cayuela, ML | 1 |
| Clarysse, L | 1 |
| Li, J | 1 |
| Goré, J | 1 |
| Jiang, LH | 1 |
| Roger, S | 1 |
| Chen, R | 1 |
| Zhang, J | 1 |
| Hu, Y | 1 |
| Wang, S | 1 |
| Chen, M | 1 |
| Chen, Q | 1 |
| Tian, S | 1 |
| Zhu, J | 1 |
| Li, KT | 1 |
| Yu, TH | 1 |
| Yu, LH | 1 |
| Bai, DQ | 1 |
| Han, YT | 1 |
| Chen, XH | 1 |
| Gao, H | 1 |
| Ye, JL | 1 |
| Wang, CB | 1 |
| Ma, JW | 1 |
| Hung, CM | 1 |
| Lin, YC | 1 |
| Ho, CT | 1 |
| Kao, JY | 1 |
| Way, TD | 1 |
| Liu, A | 2 |
| Chen, H | 1 |
| Wei, W | 1 |
| Ye, S | 1 |
| Liao, W | 1 |
| Gong, J | 1 |
| Jiang, Z | 1 |
| Wang, L | 1 |
| Lin, S | 2 |
| Ok, S | 1 |
| Kim, SM | 1 |
| Kim, C | 1 |
| Nam, D | 1 |
| Shim, BS | 1 |
| Kim, SH | 1 |
| Ahn, KS | 2 |
| Choi, SH | 1 |
| Sha, L | 1 |
| Shen, Y | 1 |
| Huang, L | 1 |
| Tang, X | 1 |
| Zhang, L | 1 |
| Lau, YK | 1 |
| Xi, L | 1 |
| Hong, RL | 1 |
| Kim, DS | 1 |
| Chen, CF | 1 |
| Hortobagyi, GN | 1 |
| Chang, C | 1 |
| Hung, MC | 1 |
2 reviews available for emodin and Neoplasm Metastasis
| Article | Year |
|---|---|
P2X7 receptor: a critical regulator and potential target for breast cancer.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Breast Neoplasms; Cat's Claw; Cations; Disease Progre | 2021 |
Potential antineoplastic effects of Aloe-emodin: a comprehensive review.
Topics: Aloe; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Transformation, | 2014 |
9 other studies available for emodin and Neoplasm Metastasis
| Article | Year |
|---|---|
Emodin inhibits epithelial‑mesenchymal transition and metastasis of triple negative breast cancer via antagonism of CC‑chemokine ligand 5 secreted from adipocytes.
Topics: Adipocytes; Adult; Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival; | 2018 |
Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cal | 2013 |
Exploring a Novel Target Treatment on Breast Cancer: Aloe-emodin Mediated Photodynamic Therapy Induced Cell Apoptosis and Inhibited Cell Metastasis.
Topics: Aloe; Apoptosis; Breast Neoplasms; Emodin; Female; Humans; Neoplasm Metastasis; Photochemotherapy | 2016 |
Physcion inhibits the metastatic potential of human colorectal cancer SW620 cells in vitro by suppressing the transcription factor SOX2.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Cell Line, Tumor; Colon; Colorectal Neoplasms; | 2016 |
Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells.
Topics: Anthraquinones; Breast Neoplasms; Carcinogenesis; Cell Movement; Down-Regulation; Emodin; Female; Gl | 2016 |
Antiproliferative and antimetastatic effects of emodin on human pancreatic cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Emodi | 2011 |
Emodin inhibits invasion and migration of prostate and lung cancer cells by downregulating the expression of chemokine receptor CXCR4.
Topics: Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Down-Regulation; Emodin; Humans; Lung Neoplasms; | 2012 |
[Experimental study on anti-metastasis effect of emodin on human pancreatic cancer].
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Emodin; Female; Humans; Matrix Metalloproteinase | 2011 |
Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties.
Topics: 3T3 Cells; Animals; Breast Neoplasms; Cell Division; Cell Transformation, Neoplastic; Emodin; Enzyme | 1998 |