emodin has been researched along with Necrosis in 7 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We demonstrate the capacity of an herbal anthraquinone aloe emodin to reduce the cytotoxicity of the proinflammatory cytokine tumor necrosis factor (TNF) towards L929 mouse fibrosarcoma and U251 human glioma cell lines." | 7.74 | Aloe emodin inhibits the cytotoxic action of tumor necrosis factor. ( Harhaji, L; Isakovic, A; Maksimovic-Ivanic, D; Mijatovic, S; Popadic, D; Todorovic-Markovic, B; Trajkovic, V, 2007) |
| "Emodin has been used as an anti-inflammatory agent and inflammation is a crucial feature of atherosclerosis." | 3.77 | Sonodynamic effect of an anti-inflammatory agent--emodin on macrophages. ( Cao, W; Cheng, J; Gao, Q; Guo, S; Jin, Y; Li, B; Li, J; Shi, S; Tian, Y; Wang, F; Wang, H; Zhang, Z; Zhu, B, 2011) |
| " Their biodistribution and pharmacokinetic properties were determined in rat models of induced necrosis." | 1.43 | Effects of skeleton structure on necrosis targeting and clearance properties of radioiodinated dianthrones. ( Feng, Y; Gao, M; Huang, D; Jiang, C; Ni, Y; Shao, H; Sun, Z; Wang, X; Yang, S; Yin, Z; Zhang, D; Zhang, J, 2016) |
| "Emodin treatment markedly and significantly mitigated all these effects." | 1.39 | Abrogation of cisplatin-induced nephrotoxicity by emodin in rats. ( Al Husseini, IS; Al-Lawati, I; Al-Salam, S; Ali, BH; Fahim, M; Nemmar, A; Waly, M; Yasin, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, J | 1 |
| Li, G | 1 |
| Han, G | 1 |
| Feng, S | 1 |
| Liu, Y | 1 |
| Chen, J | 1 |
| Liu, C | 1 |
| Zhao, L | 1 |
| Jin, F | 1 |
| Wu, L | 1 |
| Cai, B | 1 |
| Liu, X | 1 |
| Cai, H | 1 |
| Zhang, D | 1 |
| Jiang, C | 1 |
| Yang, S | 1 |
| Gao, M | 1 |
| Huang, D | 1 |
| Wang, X | 1 |
| Shao, H | 1 |
| Feng, Y | 1 |
| Sun, Z | 1 |
| Ni, Y | 1 |
| Zhang, J | 1 |
| Yin, Z | 1 |
| Gao, Q | 2 |
| Wang, F | 1 |
| Guo, S | 1 |
| Li, J | 1 |
| Zhu, B | 1 |
| Cheng, J | 1 |
| Jin, Y | 1 |
| Li, B | 1 |
| Wang, H | 1 |
| Shi, S | 1 |
| Zhang, Z | 1 |
| Cao, W | 1 |
| Tian, Y | 1 |
| Ali, BH | 1 |
| Al-Salam, S | 1 |
| Al Husseini, IS | 1 |
| Al-Lawati, I | 1 |
| Waly, M | 1 |
| Yasin, J | 1 |
| Fahim, M | 1 |
| Nemmar, A | 1 |
| Harhaji, L | 1 |
| Mijatovic, S | 1 |
| Maksimovic-Ivanic, D | 1 |
| Popadic, D | 1 |
| Isakovic, A | 1 |
| Todorovic-Markovic, B | 1 |
| Trajkovic, V | 1 |
| Lin, CC | 1 |
| Chang, CH | 1 |
| Yang, JJ | 1 |
| Namba, T | 1 |
| Hattori, M | 1 |
7 other studies available for emodin and Necrosis
| Article | Year |
|---|---|
Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway.
Topics: Animals; Cell Cycle; Cell Proliferation; Emodin; Female; Glioma; Humans; Mice; Mice, Inbred BALB C; | 2020 |
Emodin attenuates calcium overload and endoplasmic reticulum stress in AR42J rat pancreatic acinar cells.
Topics: Acinar Cells; Amylases; Animals; Apoptosis; Calcium; Cell Line; Ceruletide; Emodin; Endoplasmic Reti | 2014 |
Effects of skeleton structure on necrosis targeting and clearance properties of radioiodinated dianthrones.
Topics: Animals; Anthracenes; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Drug Design; | 2016 |
Sonodynamic effect of an anti-inflammatory agent--emodin on macrophages.
Topics: Anti-Inflammatory Agents; Apoptosis; Atherosclerosis; Cell Culture Techniques; Emodin; Fluorescent A | 2011 |
Abrogation of cisplatin-induced nephrotoxicity by emodin in rats.
Topics: Acetylglucosaminidase; Animals; Cisplatin; Creatinine; Drug Interactions; Emodin; Glutathione; Kidne | 2013 |
Aloe emodin inhibits the cytotoxic action of tumor necrosis factor.
Topics: Animals; Anthraquinones; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Emodin; Humans; | 2007 |
Hepatoprotective effects of emodin from Ventilago leiocarpa.
Topics: Acetates; Analysis of Variance; Animals; Carbon Tetrachloride; Chemical Fractionation; Chloroform; E | 1996 |