emodin has been researched along with Nasopharyngeal Carcinoma in 2 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Nasopharyngeal Carcinoma: A carcinoma that originates in the EPITHELIUM of the NASOPHARYNX and includes four subtypes: keratinizing squamous cell, non-keratinizing, basaloid squamous cell, and PAPILLARY ADENOCARCINOMA. It is most prevalent in Southeast Asian populations and is associated with EPSTEIN-BARR VIRUS INFECTIONS. Somatic mutations associated with this cancer have been identified in NPCR, BAP1, UBAP1, ERBB2, ERBB3, MLL2, PIK3CA, KRAS, NRAS, and ARID1A genes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aloe-emodin (AE) has been shown to inhibit the proliferation of several cancer cell lines, including human nasopharyngeal carcinoma (NPC) cell lines." | 8.31 | Aloe-emodin targets multiple signaling pathways by blocking ubiquitin-mediated degradation of DUSP1 in nasopharyngeal carcinoma cells. ( Chen, S; Fan, H; Guan, X; He, M; Hu, J; Li, C; Li, Q; Liu, C; Tang, J; Xiao, S; Xie, L; Yang, M; Zhang, X, 2023) |
| "Emodin is a natural anthraquinone derivative isolated from the Rheum palmatum." | 5.46 | Emodin suppresses the nasopharyngeal carcinoma cells by targeting the chloride channels. ( Chen, L; Liu, M; Ma, L; Wang, L; Yang, H; Yang, Y; Yin, Z; Zhu, L, 2017) |
| "Aloe-emodin (AE) has been shown to inhibit the proliferation of several cancer cell lines, including human nasopharyngeal carcinoma (NPC) cell lines." | 4.31 | Aloe-emodin targets multiple signaling pathways by blocking ubiquitin-mediated degradation of DUSP1 in nasopharyngeal carcinoma cells. ( Chen, S; Fan, H; Guan, X; He, M; Hu, J; Li, C; Li, Q; Liu, C; Tang, J; Xiao, S; Xie, L; Yang, M; Zhang, X, 2023) |
| "Emodin is a natural anthraquinone derivative isolated from the Rheum palmatum." | 1.46 | Emodin suppresses the nasopharyngeal carcinoma cells by targeting the chloride channels. ( Chen, L; Liu, M; Ma, L; Wang, L; Yang, H; Yang, Y; Yin, Z; Zhu, L, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S | 1 |
| Guan, X | 1 |
| Xie, L | 2 |
| Liu, C | 1 |
| Li, C | 1 |
| He, M | 1 |
| Hu, J | 1 |
| Fan, H | 1 |
| Li, Q | 1 |
| Yang, M | 1 |
| Zhang, X | 1 |
| Xiao, S | 1 |
| Tang, J | 1 |
| Ma, L | 1 |
| Yang, Y | 1 |
| Yin, Z | 1 |
| Liu, M | 1 |
| Wang, L | 1 |
| Chen, L | 1 |
| Zhu, L | 1 |
| Yang, H | 1 |
2 other studies available for emodin and Nasopharyngeal Carcinoma
| Article | Year |
|---|---|
Aloe-emodin targets multiple signaling pathways by blocking ubiquitin-mediated degradation of DUSP1 in nasopharyngeal carcinoma cells.
Topics: Aloe; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dual Specificity Phosphatase 1; Emodin; Human | 2023 |
Emodin suppresses the nasopharyngeal carcinoma cells by targeting the chloride channels.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Count; Cell Cycle; Cell Cycle Checkpoints; Cell Li | 2017 |