emodin has been researched along with Muscle Contraction in 14 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Excerpt | Relevance | Reference |
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"[3H]-ryanodine binding was dose-dependently potentiated by emodin in a biphasic manner." | 5.30 | Emodin-induced muscle contraction of mouse diaphragm and the involvement of Ca2+ influx and Ca2+ release from sarcoplasmic reticulum. ( Cheng, YW; Kang, JJ, 1998) |
"(1) Emodin inhibited the tension and amplitude of jejunum smooth muscle contraction in a dose-dependent manner (P < 0." | 3.80 | [The effect of emodin on the contraction of isolated jejunum smooth muscle of rats]. ( Gao, L; Guo, Z; Han, X; Hu, P; Jiang, LL; Ma, HJ; Yang, J; Zhang, Y, 2014) |
"To observe the effect of emodin on motility signal transduction and calcium ion in colonic smooth muscle cells (SMC) in rats with bacterial peritonitis caused multiple organ dysfunction syndrome (MODS)." | 3.72 | [Effect of emodin on motility signal transduction in colonic smooth muscle cells in rats with multiple organ dysfunction syndrome]. ( Chen, ZY; Jian, X; Ma, T; Qi, QH, 2004) |
"Emodin has a direct contractile effect on colonic smooth muscle cell." | 1.32 | Signal pathways involved in emodin-induced contraction of smooth muscle cells from rat colon. ( Dong, ZL; Ma, T; Qi, QH; Xu, J; Yang, WX, 2004) |
" Depletion of endogenous ACh in the presence of HC-3 was achieved by construction of an ACh dose-response curve, using exogenous ACh, prior to re-testing the effects of emodin in the presence of HC-3." | 1.32 | The stimulant cathartic, emodin, contracts the rat isolated ileum by triggering release of endogenous acetylcholine. ( Ali, S; Osborne, RH; Watson, MS, 2004) |
"[3H]-ryanodine binding was dose-dependently potentiated by emodin in a biphasic manner." | 1.30 | Emodin-induced muscle contraction of mouse diaphragm and the involvement of Ca2+ influx and Ca2+ release from sarcoplasmic reticulum. ( Cheng, YW; Kang, JJ, 1998) |
"Emodin is an active principle of Rheum palmatum." | 1.29 | [Study on effect of emodin on the isolated intestinal smooth muscle of guinea-pigs]. ( Jin, ZH; Lin, XZ; Ma, DL, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (28.57) | 18.2507 |
2000's | 7 (50.00) | 29.6817 |
2010's | 2 (14.29) | 24.3611 |
2020's | 1 (7.14) | 2.80 |
Authors | Studies |
---|---|
Chung, MI | 1 |
Gan, KH | 1 |
Lin, CN | 1 |
Ko, FN | 1 |
Teng, CM | 1 |
Qiu, JY | 1 |
Ma, LQ | 1 |
Liu, BB | 1 |
Zhang, WJ | 1 |
Liu, MS | 1 |
Wang, GG | 1 |
Zhao, XX | 1 |
Luo, X | 1 |
Wang, Q | 1 |
Xu, H | 1 |
Zang, DA | 1 |
Shen, J | 1 |
Peng, YB | 1 |
Zhao, P | 1 |
Xue, L | 1 |
Yu, MF | 1 |
Chen, W | 1 |
Dai, J | 1 |
Liu, QH | 1 |
Hu, P | 1 |
Yang, J | 1 |
Gao, L | 1 |
Han, X | 1 |
Jiang, LL | 1 |
Ma, HJ | 1 |
Guo, Z | 1 |
Zhang, Y | 1 |
Wu, ZX | 2 |
Yu, BP | 2 |
Xia, H | 2 |
Xu, L | 2 |
Yang, WX | 2 |
Wang, J | 2 |
Li, JY | 1 |
Chen, D | 1 |
Xiong, Y | 1 |
Wang, L | 1 |
Lv, B | 1 |
Lin, Y | 1 |
Ma, T | 2 |
Qi, QH | 2 |
Xu, J | 2 |
Dong, ZL | 1 |
Ali, S | 1 |
Watson, MS | 1 |
Osborne, RH | 1 |
Chen, ZY | 1 |
Jian, X | 1 |
Zheyu, C | 1 |
Qinghui, QI | 1 |
Lixin, L | 1 |
Tao, MA | 1 |
Zhang, L | 1 |
Lunan, Y | 1 |
Jin, ZH | 1 |
Ma, DL | 1 |
Lin, XZ | 1 |
Cheng, YW | 1 |
Kang, JJ | 1 |
Li, J | 1 |
Yang, W | 1 |
Hu, W | 1 |
Jin, Z | 1 |
Wang, X | 1 |
Xu, W | 1 |
14 other studies available for emodin and Muscle Contraction
Article | Year |
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Antiplatelet effects and vasorelaxing action of some constituents of Formosan plants.
Topics: Animals; Anthraquinones; Aorta, Thoracic; Female; In Vitro Techniques; Male; Muscle Contraction; Mus | 1993 |
Folium Sennae and emodin reverse airway smooth muscle contraction.
Topics: Acetylcholine; Animals; Bronchodilator Agents; Emodin; Lung; Male; Mice; Mice, Inbred BALB C; Muscle | 2020 |
[The effect of emodin on the contraction of isolated jejunum smooth muscle of rats].
Topics: Animals; Calcium Signaling; Emodin; Glyburide; Jejunum; Muscle Contraction; Muscle, Smooth; NG-Nitro | 2014 |
Emodin increases Ca(2+) influx through L-type Ca(2+) channel in guinea pig gallbladder smooth muscle.
Topics: Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Calcium Signaling; Dose-Response Relati | 2008 |
Emodin inhibits voltage-dependent potassium current in guinea pig gallbladder smooth muscle.
Topics: Animals; Dose-Response Relationship, Drug; Emodin; Female; Gallbladder; Guinea Pigs; In Vitro Techni | 2009 |
[Effects of emodin on cytoplasmic adenine nucleotide content in guinea pig taenia coli cells].
Topics: Adenine Nucleotides; Animals; Colon; Cytoplasm; Emodin; Guinea Pigs; Muscle Contraction; Muscle, Smo | 2001 |
Characteristics of emodin on modulating the contractility of jejunal smooth muscle.
Topics: Animals; Atropine; Constipation; Diarrhea; Diphenhydramine; Disease Models, Animal; Dose-Response Re | 2012 |
Signal pathways involved in emodin-induced contraction of smooth muscle cells from rat colon.
Topics: Animals; Azepines; Calcium; Calcium Signaling; Colon; Emodin; Enzyme Inhibitors; Muscle Contraction; | 2004 |
The stimulant cathartic, emodin, contracts the rat isolated ileum by triggering release of endogenous acetylcholine.
Topics: Acetylcholine; Animals; Atropine; Catecholamines; Cathartics; Dose-Response Relationship, Drug; Emod | 2004 |
[Effect of emodin on motility signal transduction in colonic smooth muscle cells in rats with multiple organ dysfunction syndrome].
Topics: Animals; Calcium; Colon; Emodin; Enzyme Inhibitors; Gastrointestinal Motility; In Vitro Techniques; | 2004 |
Effects of emodin on Ca2+ signal transduction of smooth muscle cells in multiple organ dysfunction syndrome.
Topics: Animals; Calcium Signaling; Colon; Emodin; Enzyme Inhibitors; Male; Multiple Organ Failure; Muscle C | 2006 |
[Study on effect of emodin on the isolated intestinal smooth muscle of guinea-pigs].
Topics: Animals; Calcium Chloride; Colon; Dose-Response Relationship, Drug; Emodin; Guinea Pigs; Ileum; In V | 1994 |
Emodin-induced muscle contraction of mouse diaphragm and the involvement of Ca2+ influx and Ca2+ release from sarcoplasmic reticulum.
Topics: Animals; Calcium; Diaphragm; Emodin; Female; Ion Transport; Male; Mice; Mice, Inbred ICR; Muscle Con | 1998 |
[Effects of emodin on the activity of K channel in guinea pig taenia coli smooth muscle cells].
Topics: Animals; Cromakalim; Dose-Response Relationship, Drug; Emodin; Female; Guinea Pigs; Male; Membrane P | 1998 |