emodin has been researched along with Multiple Myeloma in 1 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emodin is an active component of a traditional Chinese and Japanese medicine isolated from the root and rhizomes of Rheum palmatum L." | 5.34 | Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor. ( Asakura, K; Hori, M; Ikeda, Y; Kaneda, T; Kizaki, M; Maekawa, T; Muto, A; Nakazato, T; Saitoh, A; Sasaki, Y; Uchida, T; Yasuda, I; Yoshida, T, 2007) |
| "Emodin is an active component of a traditional Chinese and Japanese medicine isolated from the root and rhizomes of Rheum palmatum L." | 1.34 | Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor. ( Asakura, K; Hori, M; Ikeda, Y; Kaneda, T; Kizaki, M; Maekawa, T; Muto, A; Nakazato, T; Saitoh, A; Sasaki, Y; Uchida, T; Yasuda, I; Yoshida, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muto, A | 1 |
| Hori, M | 1 |
| Sasaki, Y | 1 |
| Saitoh, A | 1 |
| Yasuda, I | 1 |
| Maekawa, T | 1 |
| Uchida, T | 1 |
| Asakura, K | 1 |
| Nakazato, T | 1 |
| Kaneda, T | 1 |
| Kizaki, M | 1 |
| Ikeda, Y | 1 |
| Yoshida, T | 1 |
1 other study available for emodin and Multiple Myeloma
| Article | Year |
|---|---|
Emodin has a cytotoxic activity against human multiple myeloma as a Janus-activated kinase 2 inhibitor.
Topics: Apoptosis; Cell Proliferation; Emodin; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; G | 2007 |