emodin has been researched along with Mouth Neoplasms in 6 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Mouth Neoplasms: Tumors or cancer of the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study is to focus the chemopreventive potential of Emodin during 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis." | 7.88 | Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach. ( Manimaran, A; Manoharan, S, 2018) |
| " The PCNA, cyclin D1, CDK4, CDK6 and survivin expression in the buccal mucosa was utilized to evaluate the Emodin efficacy on abnormal cell proliferation during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis in golden Syrian hamsters." | 7.85 | EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS. ( Buddhan, R; Manimaran, A; Manoharan, S, 2017) |
| "The present study has evaluated the Emodin efficacy on the Akt, MAPK, ERK and DNMT expression pattern during 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinoma in golden Syrian hamsters, in order to explore its antitumor potential." | 7.83 | EMODIN EFFICACY ON THE AKT, MAPK, ERK AND DNMT EXPRESSION PATTERN DURING DMBA-INDUCED ORAL CARCINOMA IN GOLDEN SYRIAN HAMSTERS. ( Manimaran, A; Manoharan, S; Neelakandan, M, 2016) |
| "The aim of the present study is to focus the chemopreventive potential of Emodin during 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis." | 3.88 | Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach. ( Manimaran, A; Manoharan, S, 2018) |
| " The PCNA, cyclin D1, CDK4, CDK6 and survivin expression in the buccal mucosa was utilized to evaluate the Emodin efficacy on abnormal cell proliferation during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis in golden Syrian hamsters." | 3.85 | EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS. ( Buddhan, R; Manimaran, A; Manoharan, S, 2017) |
| "The present study has evaluated the Emodin efficacy on the Akt, MAPK, ERK and DNMT expression pattern during 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinoma in golden Syrian hamsters, in order to explore its antitumor potential." | 3.83 | EMODIN EFFICACY ON THE AKT, MAPK, ERK AND DNMT EXPRESSION PATTERN DURING DMBA-INDUCED ORAL CARCINOMA IN GOLDEN SYRIAN HAMSTERS. ( Manimaran, A; Manoharan, S; Neelakandan, M, 2016) |
| "Emodin can inhibit the proliferation of Tca8113 cells and affect their cell cycle distribution possibly by inhibiting the signaling pathways of cell cycle regulation." | 1.42 | [Effect of emodin on proliferation and cell cycle of human oral squamous carcinoma Tca8113 cells in vitro]. ( Jiao, K; Li, J; Wu, F; Yu, Z; Zhang, K; Zhu, Y, 2015) |
| "Moreover, Emodin inhibited oral cancer cell growth and induced caspase-dependent apoptosis by decreasing Sp1." | 1.37 | Apoptotic effect of Polygonum Cuspidatum in oral cancer cells through the regulation of specificity protein 1. ( Cho, NP; Cho, SD; Choi, ES; Choi, KH; Jeon, JG; Shim, JH; Shin, JA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manimaran, A | 3 |
| Manoharan, S | 3 |
| Neelakandan, M | 1 |
| Buddhan, R | 1 |
| Zhang, K | 1 |
| Jiao, K | 1 |
| Zhu, Y | 1 |
| Wu, F | 1 |
| Li, J | 1 |
| Yu, Z | 1 |
| Liu, MD | 1 |
| Xiong, SJ | 1 |
| Tan, F | 1 |
| Liu, Y | 1 |
| Shin, JA | 1 |
| Shim, JH | 1 |
| Jeon, JG | 1 |
| Choi, KH | 1 |
| Choi, ES | 1 |
| Cho, NP | 1 |
| Cho, SD | 1 |
6 other studies available for emodin and Mouth Neoplasms
| Article | Year |
|---|---|
EMODIN EFFICACY ON THE AKT, MAPK, ERK AND DNMT EXPRESSION PATTERN DURING DMBA-INDUCED ORAL CARCINOMA IN GOLDEN SYRIAN HAMSTERS.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Prolife | 2016 |
EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Carcinogen | 2017 |
[Effect of emodin on proliferation and cell cycle of human oral squamous carcinoma Tca8113 cells in vitro].
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin E; Cyclin-Depende | 2015 |
Physcion 8-O-β-glucopyranoside induces mitochondria-dependent apoptosis of human oral squamous cell carcinoma cells via suppressing survivin expression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; E | 2016 |
Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Squamo | 2018 |
Apoptotic effect of Polygonum Cuspidatum in oral cancer cells through the regulation of specificity protein 1.
Topics: Acetates; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspases; Cell Death; Cell Li | 2011 |