emodin has been researched along with Leukemia L 1210 in 4 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aloe-emodin has been shown to exit anticancer activity." | 5.32 | Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells. ( Chang, WC; Cheng, KC; Chung, JG; Lee, YM; Li, YC; Lin, JP, 2003) |
| "Emodin is a multifunctional Chinese traditional medicine with poor water solubility." | 1.38 | Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin. ( Lu, Y; Shan, W; Wang, T; Xiong, S; Yin, X, 2012) |
| "Aloe-emodin has been shown to exit anticancer activity." | 1.32 | Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells. ( Chang, WC; Cheng, KC; Chung, JG; Lee, YM; Li, YC; Lin, JP, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, T | 1 |
| Yin, X | 1 |
| Lu, Y | 1 |
| Shan, W | 1 |
| Xiong, S | 1 |
| Chung, JG | 1 |
| Li, YC | 1 |
| Lee, YM | 1 |
| Lin, JP | 1 |
| Cheng, KC | 1 |
| Chang, WC | 1 |
| Koyama, M | 1 |
| Takahashi, K | 1 |
| Chou, TC | 1 |
| Darzynkiewicz, Z | 2 |
| Kapuscinski, J | 2 |
| Kelly, TR | 1 |
| Watanabe, KA | 2 |
| Carter, SP | 1 |
4 other studies available for emodin and Leukemia L 1210
| Article | Year |
|---|---|
Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell | 2012 |
Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells.
Topics: 2-Acetylaminofluorene; Acetylation; Animals; Anthraquinones; Arylamine N-Acetyltransferase; Chromato | 2003 |
Intercalating agents with covalent bond forming capability. A novel type of potential anticancer agents. 2. Derivatives of chrysophanol and emodin.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Chemical Phenomena; Chemistry; DNA; DNA, Neoplasm; E | 1989 |
Effect of derivatives of chrysophanol, a new type of potential antitumor agents of anthraquinone family, on growth and cell cycle of L1210 leukemic cells.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Cell Count; Cell Cycle; Cell Survival; DNA; Emodin; | 1989 |