emodin has been researched along with Leukemia, Myeloid, Acute in 3 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we investigated the anti-leukemia effects of emodin alone or in combination with cytarabine (Ara-C) on multidrug-resistant AML HL-60/ADR cells and in a mouse xenograft model of human highly tumorigenic AML HL-60/H3 cells." | 1.48 | Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo. ( Chen, Y; Gan, D; Hu, J; Huang, Q; Lin, D; Luo, X, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 5 |
| Zheng, J | 2 |
| Gan, D | 2 |
| Zhang, N | 1 |
| Lin, Z | 2 |
| Wang, W | 1 |
| Chen, H | 1 |
| Lin, D | 2 |
| Hu, J | 3 |
| Huang, Q | 1 |
| Luo, X | 1 |
| Li, J | 1 |
| Zheng, Z | 1 |
| Liu, T | 1 |
| Lin, M | 1 |
3 other studies available for emodin and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
E35 ablates acute leukemia stem and progenitor cells in vitro and in vivo.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Lineage; Cell Proliferation; Emodin; Hematopoietic Stem C | 2020 |
Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo.
Topics: Animals; Apoptosis; Caspases; Cell Survival; Cytarabine; Drug Resistance, Neoplasm; Drug Therapy, Co | 2018 |
Emodin enhances ATRA-induced differentiation and induces apoptosis in acute myeloid leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Differentiation; Cell Pro | 2014 |