emodin has been researched along with Kidney Failure in 3 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with emodin significantly turns down the accelerated cell cycle and proliferation of MCs cultured in high glucose (HG) via inhibiting cFLIP." | 5.40 | Emodin suppresses hyperglycemia-induced proliferation and fibronectin expression in mesangial cells via inhibiting cFLIP. ( Cao, S; Gao, J; Guo, C; Su, Z; Wang, F; Wang, W, 2014) |
| "Treatment with emodin significantly turns down the accelerated cell cycle and proliferation of MCs cultured in high glucose (HG) via inhibiting cFLIP." | 1.40 | Emodin suppresses hyperglycemia-induced proliferation and fibronectin expression in mesangial cells via inhibiting cFLIP. ( Cao, S; Gao, J; Guo, C; Su, Z; Wang, F; Wang, W, 2014) |
| "Emodin treatment markedly and significantly mitigated all these effects." | 1.39 | Abrogation of cisplatin-induced nephrotoxicity by emodin in rats. ( Al Husseini, IS; Al-Lawati, I; Al-Salam, S; Ali, BH; Fahim, M; Nemmar, A; Waly, M; Yasin, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Xing, M | 1 |
| Ma, X | 1 |
| Wang, X | 1 |
| Wang, H | 1 |
| Xie, M | 1 |
| Zhang, Z | 1 |
| Zhou, J | 1 |
| Gao, J | 1 |
| Wang, F | 1 |
| Wang, W | 1 |
| Su, Z | 1 |
| Guo, C | 1 |
| Cao, S | 1 |
| Ali, BH | 1 |
| Al-Salam, S | 1 |
| Al Husseini, IS | 1 |
| Al-Lawati, I | 1 |
| Waly, M | 1 |
| Yasin, J | 1 |
| Fahim, M | 1 |
| Nemmar, A | 1 |
3 other studies available for emodin and Kidney Failure
| Article | Year |
|---|---|
Emodin disrupts the Notch1/Nrf2/GPX4 antioxidant system and promotes renal cell ferroptosis.
Topics: Animals; Antioxidants; Emodin; Ferroptosis; Kidney; Mice; NF-E2-Related Factor 2; Phospholipid Hydro | 2023 |
Emodin suppresses hyperglycemia-induced proliferation and fibronectin expression in mesangial cells via inhibiting cFLIP.
Topics: Animals; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Cycle Checkpoints; Cell P | 2014 |
Abrogation of cisplatin-induced nephrotoxicity by emodin in rats.
Topics: Acetylglucosaminidase; Animals; Cisplatin; Creatinine; Drug Interactions; Emodin; Glutathione; Kidne | 2013 |