emodin has been researched along with Kidney Diseases in 7 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to enhance renal fibrosis therapy of emodin, an innovative combination therapy based on deoxycholic acid-chitosan coated liposomes (DCS-Lips) and in situ colonic gel (IGE) was developed." | 8.12 | Deoxycholic acid-chitosan coated liposomes combined with in situ colonic gel enhances renal fibrosis therapy of emodin. ( Fan, X; Hou, Y; Piao, JG; Sun, J; Wei, Y; Xu, Z; Yao, W; Zhang, K; Zhang, Q; Zhu, L, 2022) |
| "We aim to explore the effects of emodin and its mechanisms on renal fibrosis (RF)." | 8.02 | Emodin-induced autophagic cell death hinders epithelial-mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis. ( Gu, R; He, C; Li, D; Liu, W; Lou, Y; Zhang, Q, 2021) |
| " Moreover, a unilateral ureteral obstruction-induced mouse model of renal fibrosis was established for investigating the antifibrotic effect of emodin in combination with HGF in vivo." | 7.96 | Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ-Smad Signaling Pathway. ( Chen, M; Deng, L; Hu, Y; Li, J; Liu, Y; Yang, F; Zhong, W, 2020) |
| "Our results showed that the histopathological abnormalities, the decrease in rat body weight and the abnormal renal function caused by renal fibrosis were improved by emodin." | 7.88 | Emodin ameliorates renal fibrosis in rats via TGF-β1/Smad signaling pathway and function study of Smurf 2. ( Chen, K; Deng, G; Jiang, K; Jiang, P; Li, H; Ma, L; Xiong, X; Zhang, S, 2018) |
| "In order to enhance renal fibrosis therapy of emodin, an innovative combination therapy based on deoxycholic acid-chitosan coated liposomes (DCS-Lips) and in situ colonic gel (IGE) was developed." | 4.12 | Deoxycholic acid-chitosan coated liposomes combined with in situ colonic gel enhances renal fibrosis therapy of emodin. ( Fan, X; Hou, Y; Piao, JG; Sun, J; Wei, Y; Xu, Z; Yao, W; Zhang, K; Zhang, Q; Zhu, L, 2022) |
| "We aim to explore the effects of emodin and its mechanisms on renal fibrosis (RF)." | 4.02 | Emodin-induced autophagic cell death hinders epithelial-mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis. ( Gu, R; He, C; Li, D; Liu, W; Lou, Y; Zhang, Q, 2021) |
| " Moreover, a unilateral ureteral obstruction-induced mouse model of renal fibrosis was established for investigating the antifibrotic effect of emodin in combination with HGF in vivo." | 3.96 | Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ-Smad Signaling Pathway. ( Chen, M; Deng, L; Hu, Y; Li, J; Liu, Y; Yang, F; Zhong, W, 2020) |
| "Our results showed that the histopathological abnormalities, the decrease in rat body weight and the abnormal renal function caused by renal fibrosis were improved by emodin." | 3.88 | Emodin ameliorates renal fibrosis in rats via TGF-β1/Smad signaling pathway and function study of Smurf 2. ( Chen, K; Deng, G; Jiang, K; Jiang, P; Li, H; Ma, L; Xiong, X; Zhang, S, 2018) |
| "Emodin was used to remedy the NRK-52E cell damage." | 1.62 | Emodin Attenuated the Kidney Damage of High-Fat-Diet Mice via the Upregulation of Glucagon-Like Peptide-1 Receptor. ( Liu, J; Liu, L; Song, B; Sun, Y; Wang, J; Zhang, H; Zheng, H, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, Z | 1 |
| Hou, Y | 1 |
| Sun, J | 1 |
| Zhu, L | 1 |
| Zhang, Q | 2 |
| Yao, W | 1 |
| Fan, X | 1 |
| Zhang, K | 1 |
| Piao, JG | 1 |
| Wei, Y | 1 |
| Yang, F | 1 |
| Deng, L | 1 |
| Li, J | 1 |
| Chen, M | 1 |
| Liu, Y | 1 |
| Hu, Y | 1 |
| Zhong, W | 1 |
| Liu, W | 1 |
| Gu, R | 1 |
| Lou, Y | 1 |
| He, C | 1 |
| Li, D | 1 |
| Liu, J | 1 |
| Sun, Y | 1 |
| Zheng, H | 1 |
| Wang, J | 1 |
| Liu, L | 1 |
| Song, B | 1 |
| Zhang, H | 1 |
| Ma, L | 1 |
| Li, H | 1 |
| Zhang, S | 1 |
| Xiong, X | 1 |
| Chen, K | 1 |
| Jiang, P | 1 |
| Jiang, K | 1 |
| Deng, G | 1 |
| Lee, W | 1 |
| Jeong, GS | 1 |
| Baek, MC | 1 |
| Ku, SK | 1 |
| Bae, JS | 1 |
| Son, YK | 1 |
| Lee, SM | 1 |
| An, WS | 1 |
| Kim, KH | 1 |
| Rha, SH | 1 |
| Rho, JH | 1 |
| Kim, SE | 1 |
7 other studies available for emodin and Kidney Diseases
| Article | Year |
|---|---|
Deoxycholic acid-chitosan coated liposomes combined with in situ colonic gel enhances renal fibrosis therapy of emodin.
Topics: Animals; Caco-2 Cells; Chitosan; Deoxycholic Acid; DNA, Ribosomal; Dysbiosis; Emodin; Female; Fibros | 2022 |
Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ-Smad Signaling Pathway.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Emodin; Fibrosis | 2020 |
Emodin-induced autophagic cell death hinders epithelial-mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis.
Topics: Animals; Autophagic Cell Death; Bone Morphogenetic Protein 7; Cells, Cultured; Emodin; Epithelial-Me | 2021 |
Emodin Attenuated the Kidney Damage of High-Fat-Diet Mice via the Upregulation of Glucagon-Like Peptide-1 Receptor.
Topics: Anilides; Animals; Body Weight; Cholesterol, LDL; Diet, High-Fat; Emodin; Enzyme-Linked Immunosorben | 2021 |
Emodin ameliorates renal fibrosis in rats via TGF-β1/Smad signaling pathway and function study of Smurf 2.
Topics: Animals; Body Weight; Emodin; Fibrosis; Gene Expression Regulation; Kidney; Kidney Diseases; Kidney | 2018 |
Renal protective effects of aloin in a mouse model of sepsis.
Topics: Animals; Cell Line; Emodin; I-kappa B Proteins; Interleukin-6; Kidney; Kidney Diseases; Lipid Peroxi | 2019 |
The role of protein kinase CK2 in cyclosporine-induced nephropathy in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Casein Kinase II; Caspase 3; Casp | 2013 |