Page last updated: 2024-10-26

emodin and Inflammation

emodin has been researched along with Inflammation in 72 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Emodin alleviated the I/R-induced lung dysfunction, lung damages, and inflammation."8.31Emodin alleviates lung ischemia-reperfusion injury by suppressing gasdermin D-mediated pyroptosis in rats. ( Ai, F; Chen, Z; Jin, T; Kong, L; Lu, R; Wang, D; Xiong, Z; Zhang, M; Zhou, J, 2023)
"Different nociceptive models induced with heat and chemicals were used to assess the potency of emodin in alleviating pain."8.31Emodin Reduces Inflammatory and Nociceptive Responses in Different Pain-and Inflammation-Induced Mouse Models. ( Guan, L; Li, J; Zhang, X, 2023)
"Emodin significantly ameliorated management of cystitis, reduced the amount of inflammatory cytokines (tumor necrosis factor-α, monocyte chemoattractant protein-1, interleukin-1β, interleukin-8, and interleukin-6) in models, as well as reducing the synthesis of fibrosis marker including collagen1, collagen3, vimentin, fibronectin and α-smooth muscle actin."8.31Emodin inhibits bladder inflammation and fibrosis in mice with interstitial cystitis by regulating JMJD3. ( Huang, M; Lai, J; Liu, X; Luo, S; Su, H; Tang, H; Xin, K; Zhu, Y, 2023)
"This work reports novel chitosan functionalized graphene oxide (GO) nanocomposites combined fluorescence imaging and therapeutic functions in one agent, which can serve as a promising alternative to alleviate related diseases caused hyperinflammation."8.02Chitosan functionalized graphene oxide nanocomposites for fluorescence imaging of apoptotic processes and targeted anti-inflammation study. ( Li, Y; Miao, J; Shao, Y; Si, H; Sun, Y; Xu, Y; Yang, Y, 2021)
"The aim of this experiment was to evaluate the efficacy of emodin on LPS-provoked alveolar hypercoagulation and excessive pulmonary inflammation in ARDS, and its potential mechanism."7.96Emodin improves alveolar hypercoagulation and inhibits pulmonary inflammation in LPS-provoked ARDS in mice via NF-κB inactivation. ( Cheng, Y; He, T; Li, S; Li, X; Liu, B; Shen, F; Wu, Y; Yang, G; Zheng, X, 2020)
"The aim of this study was to explore the effect of emodin on lipid accumulation and inflammation in hepatocytes."7.91[Effects of emodin on lipid accumulation and inflammation in hepatocytes]. ( Dai, YH; Xiao, HB; Yang, XW; Zhang, YH, 2019)
"BACKGROUND This study investigated the effects and underlying mechanisms of emodin on cough variant asthma (CVA) in mice."7.91Emodin Alleviates the Airway Inflammation of Cough Variant Asthma in Mice by Regulating the Notch Pathway. ( Hua, S; Liu, F; Wang, M, 2019)
"Emodin is an anthraquinone derived from Chinese herb that exerts anti-inflammation effects."7.83Emodin alleviates jejunum injury in rats with sepsis by inhibiting inflammation response. ( Chen, YK; Fan, X; Fu, HY; Liu, DD; Wan, B; Xu, YK; Yin, JT; Zhang, H, 2016)
"Emodin upregulates glucose metabolism, decreases lipolysis, and inhibits inflammation in C2C12 myotubes and 3T3-L1 adipocytes."7.81Emodin up-regulates glucose metabolism, decreases lipolysis, and attenuates inflammation in vitro. ( Deng, Y; Lv, P; Xu, J; Yang, J; Yang, Y; Zhang, D; Zhang, R; Zhang, X; Zhu, R, 2015)
" In AT-II cells induced by mechanical stretch, due to intervention effect of emodin lipid nano-microbubble, the the protein expressions of p-P38, p-ERK, p-JNK and the inflammation cytokine release levels of TNF-alpha, IL-1beta, IL-6 were significantly decreased."7.79[Effect of emodin lipid nano-microbubble on MAPK signal pathway and inflammation cytokine in AT-II cells by mechanical stretch]. ( Jiang, YN; Mo, HY; Ren, H, 2013)
"Emodin treatment attenuated testicular IRI and inhibited pyroptosis."5.91Emodin alleviates testicular ischemia-reperfusion injury through the inhibition of NLRP3-mediated pyroptosis. ( Cheng, F; He, KX; Li, W; Ning, JZ, 2023)
"Emodin was used as a post-treatment for its potential to be neuroprotective in the treatment of chronic constriction injury-induced NP."5.91Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. ( Ali, F; Alvi, AM; Badshah, I; Bungau, S; Hassan, SSU; Imran, M; Kandeel, M; Minhas, AM; Qazi, NG, 2023)
"Emodin treatment statistically elevated mechanical pain sensitivity, suppressed spontaneous pain, recovered motor coordination, decreased spinal inflammation score and IL-1β expression, increased spinal Nrf2 expression and SOD activity."5.72Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress. ( Chen, CX; Cheng, DW; Cheng, ML; Hu, YD; Li, D; Liu, L; Tang, Q; Xie, M; Yue, YF; Zhu, HL, 2022)
"Emodin has been shown to exert strong anti-inflammatory property via acting on macrophages in a range of disease models."5.62Emodin inhibits lipid accumulation and inflammation in adipose tissue of high-fat diet-fed mice by inducing M2 polarization of adipose tissue macrophages. ( Peng, J; Wang, F; Wang, X; Xu, X; Yu, F; Yu, N; Zhang, L; Zhao, Y; Zhou, J, 2021)
"Emodin (EMO) is a major bioactive constituent of CMD that has apparent therapeutic efficacy against obesity and fatty liver."5.62Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway. ( Cai, J; Deng, Z; Guo, J; Huang, Q; Lan, S; Liu, H; Liu, M; Liu, Z; Pan, Z; Shen, C; Si, Y; Tu, H; Wu, H; Wu, S; Xian, S; Xin, X; Yu, Y; Zhang, J; Zheng, M; Zhong, C; Zhong, Y; Zhu, Z, 2021)
"BACKGROUND Idiopathic pulmonary fibrosis (IPF) can severely damage lung function, which may result in death."5.48Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats. ( Liu, XL; Tian, SL; Xu, QB; Yang, Y, 2018)
"Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with few treatment options and poor prognosis."5.43Emodin alleviates bleomycin-induced pulmonary fibrosis in rats. ( Cheng, W; Guan, R; Guo, Y; Jiang, L; Shen, L; Song, N; Wang, X; Yan, X; Zhao, X, 2016)
"Inflammation is a defense and protective response to multiple harmful stimuli."5.43Emodin suppresses LPS-induced inflammation in RAW264.7 cells through a PPARγ-dependent pathway. ( Feng, SJ; Yu, HP; Zhang, W; Zhu, T, 2016)
" Dose-response studies showed that emodin at 100 µM was not cytotoxic to naive cells, and that the same dose caused proliferation to be significantly reduced in ConA-stimulated cells."5.43Emodin inhibits splenocyte proliferation and inflammation by modulating cytokine responses in a mouse model system. ( Sharma, R; Tiku, AB, 2016)
"Treatment with emodin significantly attenuated HS inflammation, as determined by histopathological assessment of the scar elevation index, collagen structure and inflammation (P<0."5.42Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin. ( Liu, C, 2015)
"Emodin-treated HFD/HF rats were protected from hepatosteatosis and metabolic derangements usually observed in HFD/HF animals."5.38Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats. ( Alisi, A; Bruscalupi, G; Ceccarelli, S; Gnani, D; Massimi, M; Nobili, V; Panera, N; Pastore, A; Piemonte, F; Tozzi, G, 2012)
"Myocarditis is an inflammatory disease of the heart and a major cause of dilated cardiomyopathy that can lead to heart failure and sudden death in young adults."5.38Emodin, a naturally occurring anthraquinone, ameliorates experimental autoimmune myocarditis in rats. ( Bai, JH; Hu, J; Li, Z; Song, ZC; Wang, ZS, 2012)
"Severe acute pancreatitis (SAP) characterized by atrocious progression and numerous complications often leads to a high mortality rate due to hypermetabolism, systemic inflammatory response syndrome (SIRS), and multiple organs dysfunction syndrome (MODS)."5.34The effect of emodin-assisted early enteral nutrition on severe acute pancreatitis and secondary hepatic injury. ( Gao, Y; Jiang, HC; Meng, QH; Sun, B; Wang, G, 2007)
" In the same dosage it also showed antiulcer activity against 4 hr pylorus-ligated, aspirin and immobilization stress-induced gastric ulcers in rats."5.28Antiulcerogenic and anti-inflammatory effects of emodin, isolated from Rhamnus triquerta wall. ( Das Gupta, G; Goel, RK; Pandey, VB; Ram, SN, 1991)
"Different nociceptive models induced with heat and chemicals were used to assess the potency of emodin in alleviating pain."4.31Emodin Reduces Inflammatory and Nociceptive Responses in Different Pain-and Inflammation-Induced Mouse Models. ( Guan, L; Li, J; Zhang, X, 2023)
"Emodin alleviated the I/R-induced lung dysfunction, lung damages, and inflammation."4.31Emodin alleviates lung ischemia-reperfusion injury by suppressing gasdermin D-mediated pyroptosis in rats. ( Ai, F; Chen, Z; Jin, T; Kong, L; Lu, R; Wang, D; Xiong, Z; Zhang, M; Zhou, J, 2023)
"Emodin significantly ameliorated management of cystitis, reduced the amount of inflammatory cytokines (tumor necrosis factor-α, monocyte chemoattractant protein-1, interleukin-1β, interleukin-8, and interleukin-6) in models, as well as reducing the synthesis of fibrosis marker including collagen1, collagen3, vimentin, fibronectin and α-smooth muscle actin."4.31Emodin inhibits bladder inflammation and fibrosis in mice with interstitial cystitis by regulating JMJD3. ( Huang, M; Lai, J; Liu, X; Luo, S; Su, H; Tang, H; Xin, K; Zhu, Y, 2023)
"Findings will provide timely information on the safety, efficacy, and optimal dosing of t-PA to treat moderate/severe COVID-19-induced ARDS, which can be rapidly adapted to a phase III trial (NCT04357730; FDA IND 149634)."4.21 ( Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; 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Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y, 2022)
" By stimulating macrophages with imiquimod (IMQ) to model the inflammation in psoriasis, it was found that the anthraquinones significantly reduced IL-6, IL-23, and TNF."4.12A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency. ( Alalaiwe, A; Chuang, SY; Fang, JY; Huang, TH; Lin, CF; Nguyen, TMH; Wang, PW, 2022)
"This work reports novel chitosan functionalized graphene oxide (GO) nanocomposites combined fluorescence imaging and therapeutic functions in one agent, which can serve as a promising alternative to alleviate related diseases caused hyperinflammation."4.02Chitosan functionalized graphene oxide nanocomposites for fluorescence imaging of apoptotic processes and targeted anti-inflammation study. ( Li, Y; Miao, J; Shao, Y; Si, H; Sun, Y; Xu, Y; Yang, Y, 2021)
"The aim of this experiment was to evaluate the efficacy of emodin on LPS-provoked alveolar hypercoagulation and excessive pulmonary inflammation in ARDS, and its potential mechanism."3.96Emodin improves alveolar hypercoagulation and inhibits pulmonary inflammation in LPS-provoked ARDS in mice via NF-κB inactivation. ( Cheng, Y; He, T; Li, S; Li, X; Liu, B; Shen, F; Wu, Y; Yang, G; Zheng, X, 2020)
"BACKGROUND This study investigated the effects and underlying mechanisms of emodin on cough variant asthma (CVA) in mice."3.91Emodin Alleviates the Airway Inflammation of Cough Variant Asthma in Mice by Regulating the Notch Pathway. ( Hua, S; Liu, F; Wang, M, 2019)
"The aim of this study was to explore the effect of emodin on lipid accumulation and inflammation in hepatocytes."3.91[Effects of emodin on lipid accumulation and inflammation in hepatocytes]. ( Dai, YH; Xiao, HB; Yang, XW; Zhang, YH, 2019)
" In an effort to reduce uterine inflammatory responses induced by Leptospira, we evaluated the anti-inflammation effects of emodin, thymol, and astragalin in a mouse model."3.85Inhibitory Effects of Emodin, Thymol, and Astragalin on Leptospira interrogans-Induced Inflammatory Response in the Uterine and Endometrium Epithelial Cells of Mice. ( Cao, Y; Ding, Z; Fu, Y; Lu, X; Wang, W; Zhang, N; Zhang, W; Zhou, X, 2017)
"Emodin is an anthraquinone derived from Chinese herb that exerts anti-inflammation effects."3.83Emodin alleviates jejunum injury in rats with sepsis by inhibiting inflammation response. ( Chen, YK; Fan, X; Fu, HY; Liu, DD; Wan, B; Xu, YK; Yin, JT; Zhang, H, 2016)
" Emodin is a Chinese herb-derived compound and has shown potential to inhibit inflammation in various settings."3.83Emodin Bidirectionally Modulates Macrophage Polarization and Epigenetically Regulates Macrophage Memory. ( Altomare, D; Fan, D; Hui, Y; Iwanowycz, S; Wang, J, 2016)
"Emodin upregulates glucose metabolism, decreases lipolysis, and inhibits inflammation in C2C12 myotubes and 3T3-L1 adipocytes."3.81Emodin up-regulates glucose metabolism, decreases lipolysis, and attenuates inflammation in vitro. ( Deng, Y; Lv, P; Xu, J; Yang, J; Yang, Y; Zhang, D; Zhang, R; Zhang, X; Zhu, R, 2015)
"Emodin, an active constituent of oriental herbs, is widely used to treat allergy, inflammation, and other symptoms."3.81Anti-inflammatory effect of emodin via attenuation of NLRP3 inflammasome activation. ( Han, JW; Heo, KH; Jeong, JH; Kang, TB; Kwak, SB; Lee, KH; Shim, DW; Shin, WY; Sim, EJ, 2015)
"This study aimed to investigate the effects of emodin on different inflammation responses of macrophages induced by ATP, the natural ligand of P2X₇R."3.80Emodin inhibits ATP-induced IL-1β secretion, ROS production and phagocytosis attenuation in rat peritoneal macrophages via antagonizing P2X₇ receptor. ( Hu, F; Li, J; Wang, X; Wang, Y; Zhu, S, 2014)
" In AT-II cells induced by mechanical stretch, due to intervention effect of emodin lipid nano-microbubble, the the protein expressions of p-P38, p-ERK, p-JNK and the inflammation cytokine release levels of TNF-alpha, IL-1beta, IL-6 were significantly decreased."3.79[Effect of emodin lipid nano-microbubble on MAPK signal pathway and inflammation cytokine in AT-II cells by mechanical stretch]. ( Jiang, YN; Mo, HY; Ren, H, 2013)
"Curcumin is an active element from the root of curcuma longa with extensive beneficial properties, including antioxidant, anti-inflammatory activity, and inhibitory effects on cell apoptosis."2.72Herbal antioxidants in dialysis patients: a review of potential mechanisms and medical implications. ( Alirezaei, A; Asgharpour, M, 2021)
"Emodin is a pleiotropic molecule capable of interacting with several major molecular targets including NF-κB, casein kinase II, HER2/neu, HIF-1α, AKT/mTOR, STAT3, CXCR4, topoisomerase II, p53, p21, and androgen receptors which are involved in inflammation and cancer."2.49Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer. ( Ahn, KS; Kumar, AP; Sethi, G; Shanmugam, MK; Shrimali, D; Tan, BK; Zhang, J, 2013)
"Emodin was used as a post-treatment for its potential to be neuroprotective in the treatment of chronic constriction injury-induced NP."1.91Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. ( Ali, F; Alvi, AM; Badshah, I; Bungau, S; Hassan, SSU; Imran, M; Kandeel, M; Minhas, AM; Qazi, NG, 2023)
"Emodin treatment attenuated testicular IRI and inhibited pyroptosis."1.91Emodin alleviates testicular ischemia-reperfusion injury through the inhibition of NLRP3-mediated pyroptosis. ( Cheng, F; He, KX; Li, W; Ning, JZ, 2023)
"Emodin treatment statistically elevated mechanical pain sensitivity, suppressed spontaneous pain, recovered motor coordination, decreased spinal inflammation score and IL-1β expression, increased spinal Nrf2 expression and SOD activity."1.72Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress. ( Chen, CX; Cheng, DW; Cheng, ML; Hu, YD; Li, D; Liu, L; Tang, Q; Xie, M; Yue, YF; Zhu, HL, 2022)
"Further, Mice NAFLD were established by methionine and choline deficiency diet (MCD) to verify the effect of RFAs on ameliorating NAFLD by inhibiting NLRP3 inflammasome."1.72Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome. ( Azami, NLB; Bian, Y; Lu, B; Ma, F; Sun, M; Wang, D; Wei, G; Wu, C, 2022)
"Emodin (EMO) is a major bioactive constituent of CMD that has apparent therapeutic efficacy against obesity and fatty liver."1.62Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway. ( Cai, J; Deng, Z; Guo, J; Huang, Q; Lan, S; Liu, H; Liu, M; Liu, Z; Pan, Z; Shen, C; Si, Y; Tu, H; Wu, H; Wu, S; Xian, S; Xin, X; Yu, Y; Zhang, J; Zheng, M; Zhong, C; Zhong, Y; Zhu, Z, 2021)
"Emodin has been shown to exert strong anti-inflammatory property via acting on macrophages in a range of disease models."1.62Emodin inhibits lipid accumulation and inflammation in adipose tissue of high-fat diet-fed mice by inducing M2 polarization of adipose tissue macrophages. ( Peng, J; Wang, F; Wang, X; Xu, X; Yu, F; Yu, N; Zhang, L; Zhao, Y; Zhou, J, 2021)
"Depression is a complex neuropsychiatric disease involved multiple targets and signaling pathways."1.62Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation. ( Fang, YY; Su, HF; Tian, Q; Wang, XM; Ye, CY; Zeng, P; Zhang, T, 2021)
"Emodin is a natural product extracted from Rheum palmatum."1.51Emodin Attenuates Lipopolysaccharide-Induced Injury via Down-Regulation of miR-223 in H9c2 Cells. ( Jiang, Z; Yang, Y; Zhuge, D, 2019)
"BACKGROUND Idiopathic pulmonary fibrosis (IPF) can severely damage lung function, which may result in death."1.48Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats. ( Liu, XL; Tian, SL; Xu, QB; Yang, Y, 2018)
" Dose-response studies showed that emodin at 100 µM was not cytotoxic to naive cells, and that the same dose caused proliferation to be significantly reduced in ConA-stimulated cells."1.43Emodin inhibits splenocyte proliferation and inflammation by modulating cytokine responses in a mouse model system. ( Sharma, R; Tiku, AB, 2016)
"Inflammation is a defense and protective response to multiple harmful stimuli."1.43Emodin suppresses LPS-induced inflammation in RAW264.7 cells through a PPARγ-dependent pathway. ( Feng, SJ; Yu, HP; Zhang, W; Zhu, T, 2016)
"Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with few treatment options and poor prognosis."1.43Emodin alleviates bleomycin-induced pulmonary fibrosis in rats. ( Cheng, W; Guan, R; Guo, Y; Jiang, L; Shen, L; Song, N; Wang, X; Yan, X; Zhao, X, 2016)
"Severe acute pancreatitis (SAP) results in high mortality."1.43Protective Effects of Emodin-Induced Neutrophil Apoptosis via the Ca ( Chen, HL; Liu, JJ; Shang, D; Sun, FL; Teng, YS; Wang, GJ; Wang, Y; Xia, SL; Xiang, H; Zhang, GX, 2016)
"Treatment with emodin significantly attenuated HS inflammation, as determined by histopathological assessment of the scar elevation index, collagen structure and inflammation (P<0."1.42Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin. ( Liu, C, 2015)
"Treatment with emodin obviously ameliorated pancreatic injury and decreased the release of amylase and inflammatory cytokines."1.39Effect of emodin on endoplasmic reticulum stress in rats with severe acute pancreatitis. ( Cai, B; Cai, H; Li, H; Liu, X; Wu, L; Zheng, S, 2013)
"Myocarditis is an inflammatory disease of the heart and a major cause of dilated cardiomyopathy that can lead to heart failure and sudden death in young adults."1.38Emodin, a naturally occurring anthraquinone, ameliorates experimental autoimmune myocarditis in rats. ( Bai, JH; Hu, J; Li, Z; Song, ZC; Wang, ZS, 2012)
"Emodin-treated HFD/HF rats were protected from hepatosteatosis and metabolic derangements usually observed in HFD/HF animals."1.38Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats. ( Alisi, A; Bruscalupi, G; Ceccarelli, S; Gnani, D; Massimi, M; Nobili, V; Panera, N; Pastore, A; Piemonte, F; Tozzi, G, 2012)
"Severe acute pancreatitis (SAP) characterized by atrocious progression and numerous complications often leads to a high mortality rate due to hypermetabolism, systemic inflammatory response syndrome (SIRS), and multiple organs dysfunction syndrome (MODS)."1.34The effect of emodin-assisted early enteral nutrition on severe acute pancreatitis and secondary hepatic injury. ( Gao, Y; Jiang, HC; Meng, QH; Sun, B; Wang, G, 2007)
" In the same dosage it also showed antiulcer activity against 4 hr pylorus-ligated, aspirin and immobilization stress-induced gastric ulcers in rats."1.28Antiulcerogenic and anti-inflammatory effects of emodin, isolated from Rhamnus triquerta wall. ( Das Gupta, G; Goel, RK; Pandey, VB; Ram, SN, 1991)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.39)18.2507
2000's2 (2.78)29.6817
2010's43 (59.72)24.3611
2020's26 (36.11)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Stompor-Gorący, M1
Wang, Y8
Zou, Z1
Jaisi, A1
Olatunji, OJ1
Lin, CF1
Chuang, SY1
Huang, TH1
Nguyen, TMH1
Wang, PW1
Alalaiwe, A1
Fang, JY1
Wang, B1
Liu, Y5
Jiang, R1
Liu, Z2
Gao, H1
Chen, F1
Mei, J1
Zheng, K1
Lv, B1
Wu, L2
Wang, C1
Xu, H1
Li, X6
Wu, Z1
Zhao, Y4
Zheng, Z2
Zhang, X4
Li, J4
Guan, L1
Wu, C2
Bian, Y1
Lu, B1
Wang, D2
Azami, NLB1
Wei, G1
Ma, F1
Sun, M3
Yang, HY1
Wu, J1
Lu, H2
Cheng, ML3
Wang, BH1
Zhu, HL3
Liu, L5
Xie, M3
Cheng, DW2
Yue, YF2
Chen, CX2
Hu, YD2
Tang, Q2
Li, D3
Jin, T1
Ai, F1
Zhou, J3
Kong, L2
Xiong, Z1
Lu, R1
Chen, Z1
Zhang, M1
He, KX1
Ning, JZ1
Li, W1
Cheng, F1
Badshah, I1
Qazi, NG1
Ali, F1
Minhas, AM1
Alvi, AM1
Kandeel, M1
Imran, M1
Hassan, SSU1
Bungau, S1
Lei, F1
Zeng, F1
Yu, X3
Deng, Y2
Zhang, Z1
Xu, M1
Ding, N1
Tian, J1
Li, C3
Lai, J1
Liu, X4
Su, H2
Zhu, Y2
Xin, K1
Huang, M1
Luo, S1
Tang, H1
Zang, L1
Song, Y2
Yu, F2
Nese, M1
Riboli, G1
Brighetti, G1
Sassi, V1
Camela, E1
Caselli, G1
Sassaroli, S1
Borlimi, R1
Aucoin, M1
Cooley, K1
Saunders, PR1
Carè, J1
Anheyer, D1
Medina, DN1
Cardozo, V1
Remy, D1
Hannan, N1
Garber, A1
Velayos, M1
Muñoz-Serrano, AJ1
Estefanía-Fernández, K1
Sarmiento Caldas, MC1
Moratilla Lapeña, L1
López-Santamaría, M1
López-Gutiérrez, JC1
Zhang, J3
Shen, S1
Zhang, B2
Yu, WW1
Toyoda, H1
Huang, DQ1
Le, MH1
Nguyen, MH1
Huang, R1
Zhu, L1
Wang, J8
Xue, L1
Yan, X3
Huang, S1
Li, Y9
Xu, T1
Ji, F1
Ming, F1
Cheng, J1
Zhao, H1
Hong, S1
Chen, K2
Zhao, XA1
Zou, L2
Sang, D1
Shao, H1
Guan, X1
Chen, X2
Chen, Y4
Wei, J1
Zhu, C1
Moore, HB1
Barrett, CD1
Moore, EE1
Jhunjhunwala, R1
McIntyre, RC1
Moore, PK1
Hajizadeh, N1
Talmor, DS1
Sauaia, A1
Yaffe, MB1
Liu, C5
Lin, Y1
Dong, Y2
Wu, Y2
Bao, Y1
Yan, H2
Ma, J2
Fernández-Cuadros, ME1
Albaladejo-Florín, MJ1
Álava-Rabasa, S1
Usandizaga-Elio, I1
Martinez-Quintanilla Jimenez, D1
Peña-Lora, D1
Neira-Borrajo, I1
López-Muñoz, MJ1
Rodríguez-de-Cía, J1
Pérez-Moro, OS1
Abdallah, M1
Alsaleh, H1
Baradwan, A1
Alfawares, R1
Alobaid, A1
Rasheed, A1
Soliman, I1
Wendel Garcia, PD1
Fumeaux, T1
Guerci, P1
Heuberger, DM1
Montomoli, J2
Roche-Campo, F1
Schuepbach, RA1
Hilty, MP1
Poloni, TE1
Carlos, AF1
Cairati, M1
Cutaia, C1
Medici, V1
Marelli, E1
Ferrari, D1
Galli, A1
Bognetti, P1
Davin, A1
Cirrincione, A1
Ceretti, A1
Cereda, C1
Ceroni, M1
Tronconi, L1
Vitali, S1
Guaita, A1
Leeds, JS1
Raviprakash, V1
Jacques, T1
Scanlon, N1
Cundall, J1
Leeds, CM1
Riva, A1
Gray, EH1
Azarian, S1
Zamalloa, A1
McPhail, MJW1
Vincent, RP1
Williams, R1
Chokshi, S1
Patel, VC1
Edwards, LA1
Alqarawi, W1
Birnie, DH1
Golian, M1
Nair, GM1
Nery, PB1
Klein, A1
Davis, DR1
Sadek, MM1
Neilipovitz, D1
Johnson, CB1
Green, MS1
Redpath, C1
Miller, DC1
Beamer, P1
Billheimer, D1
Subbian, V1
Sorooshian, A1
Campbell, BS1
Mosier, JM1
Novaretti, JV1
Astur, DC1
Cavalcante, ELB1
Kaleka, CC1
Amaro, JT1
Cohen, M1
Huang, W2
Li, T1
Ling, Y1
Qian, ZP1
Zhang, YY1
Huang, D1
Xu, SB1
Liu, XH1
Xia, L1
Yang, Y7
Lu, SH1
Lu, HZ1
Zhang, R3
Ma, JX1
Tang, S1
Li, CM1
Wan, J1
Wang, JF1
Ma, JQ1
Luo, JJ1
Chen, HY2
Mi, SL1
Chen, SY1
Su, YG1
Ge, JB1
Milheiro, SA1
Gonçalves, J1
Lopes, RMRM1
Madureira, M1
Lobo, L1
Lopes, A1
Nogueira, F1
Fontinha, D1
Prudêncio, M1
M Piedade, MF1
Pinto, SN1
Florindo, PR1
Moreira, R1
Castillo-Lora, J1
Delley, MF1
Laga, SM1
Mayer, JM1
Sutjarit, N1
Thongon, N1
Weerachayaphorn, J1
Piyachaturawat, P1
Suksamrarn, A1
Suksen, K1
Papachristou, DJ1
Blair, HC1
Hu, Y1
Shen, P1
Zeng, N1
Wang, L3
Yan, D2
Cui, L1
Yang, K2
Zhai, C1
Yang, M1
Lao, X1
Sun, J1
Ma, N1
Wang, S1
Ye, W1
Guo, P1
Rahimi, S1
Singh, MP1
Gupta, J1
Nakanishi, I1
Ohkubo, K1
Shoji, Y1
Fujitaka, Y1
Shimoda, K1
Matsumoto, KI1
Fukuhara, K1
Hamada, H1
van der Boom, T1
Gruppen, EG1
Lefrandt, JD1
Connelly, MA1
Links, TP1
Dullaart, RPF1
Berry, JD1
Bedlack, R1
Mathews, D1
Agnese, W1
Apple, S1
Meloncelli, S1
Divizia, M1
Germani, G1
Adefegha, SA1
Bottari, NB1
Leal, DB1
de Andrade, CM1
Schetinger, MR1
Martínez-Velasco, A1
Perez-Ortiz, AC1
Antonio-Aguirre, B1
Martínez-Villaseñor, L1
Lira-Romero, E1
Palacio-Pastrana, C1
Zenteno, JC1
Ramirez, I1
Zepeda-Palacio, C1
Mendoza-Velásquez, C1
Camacho-Ordóñez, A1
Ortiz Bibriesca, DM1
Estrada-Mena, FJ1
Martin, BL1
Thompson, LC1
Kim, YH2
Snow, SJ1
Schladweiler, MC1
Phillips, P1
Harmon, M1
King, C1
Richards, J1
George, I1
Haykal-Coates, N1
Gilmour, MI1
Kodavanti, UP1
Hazari, MS1
Farraj, AK1
Shen, Z1
Zou, Y1
Gao, K1
Lazar, S1
Wurtzel, JGT1
Ma, P1
Goldfinger, LE1
Vukelic, M1
Laloo, A1
Kyttaris, VC1
Chen, R1
Chen, J2
Xun, J1
Hu, Z1
Huang, Q3
Steinhart, C1
Shen, Y2
Mansuri, A1
Lokhande, K1
Kore, S1
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Reviews

6 reviews available for emodin and Inflammation

ArticleYear
The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb-A Summary Update.
    International journal of molecular sciences, 2021, Sep-01, Volume: 22, Issue:17

    Topics: Emodin; Humans; Infections; Inflammation; Neoplasms; Rheum

2021
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
Emodin in atherosclerosis prevention: Pharmacological actions and therapeutic potential.
    European journal of pharmacology, 2021, Jan-05, Volume: 890

    Topics: Animals; Atherosclerosis; Blood Platelets; Drugs, Chinese Herbal; Emodin; Endothelium; Humans; Infla

2021
Herbal antioxidants in dialysis patients: a review of potential mechanisms and medical implications.
    Renal failure, 2021, Volume: 43, Issue:1

    Topics: Antioxidants; Cardiovascular Diseases; Curcumin; Emodin; Humans; Inflammation; Oxidative Stress; Pla

2021
Sonodynamic therapy: A potential treatment for atherosclerosis.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chal

2018
Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer.
    Cancer letters, 2013, Dec-01, Volume: 341, Issue:2

    Topics: Emodin; Humans; Inflammation; Models, Biological; Neoplasms; NF-kappa B; Protein Kinase Inhibitors;

2013

Trials

1 trial available for emodin and Inflammation

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain;

2022

Other Studies

66 other studies available for emodin and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Unravelling the Protective Effects of Emodin Against Cyclophosphamide Induced Gonadotoxicity in Male Wistar Rats.
    Drug design, development and therapy, 2021, Volume: 15

    Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Cyclophosphamide; Emodin; Inflammation; Ma

2021
A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 145

    Topics: Administration, Topical; Animals; Anthraquinones; Anti-Inflammatory Agents; Cytokines; Disease Model

2022
Emodin relieves the inflammation and pyroptosis of lipopolysaccharide-treated 1321N1 cells by regulating methyltransferase-like 3 -mediated NLR family pyrin domain containing 3 expression.
    Bioengineered, 2022, Volume: 13, Issue:3

    Topics: Caspase 1; Emodin; Humans; Inflammation; Interleukin-10; Interleukin-6; Lipopolysaccharides; Methylt

2022
Protecting effect of emodin in experimental autoimmune encephalomyelitis mice by inhibiting microglia activation and inflammation via Myd88/PI3K/Akt/NF-κB signalling pathway.
    Bioengineered, 2022, Volume: 13, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Emodin; Encephalomyelitis, Autoimmune, Experimental; Inflammation

2022
Emodin Reduces Inflammatory and Nociceptive Responses in Different Pain-and Inflammation-Induced Mouse Models.
    Combinatorial chemistry & high throughput screening, 2023, Volume: 26, Issue:5

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; E

2023
Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome.
    Journal of translational medicine, 2022, 06-28, Volume: 20, Issue:1

    Topics: Animals; Anthraquinones; Emodin; Inflammasomes; Inflammation; Mice; NLR Family, Pyrin Domain-Contain

2022
Emodin suppresses oxaliplatin-induced neuropathic pain by inhibiting COX2/NF-κB mediated spinal inflammation.
    Journal of biochemical and molecular toxicology, 2023, Volume: 37, Issue:1

    Topics: Animals; Cyclooxygenase 2; Emodin; Inflammation; Neuralgia; NF-kappa B; Oxaliplatin; Quality of Life

2023
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress.
    Molecular pain, 2022, Volume: 18

    Topics: AMP-Activated Protein Kinases; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Chronic Pain

2022
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress.
    Molecular pain, 2022, Volume: 18

    Topics: AMP-Activated Protein Kinases; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Chronic Pain

2022
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress.
    Molecular pain, 2022, Volume: 18

    Topics: AMP-Activated Protein Kinases; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Chronic Pain

2022
Emodin alleviates arthritis pain through reducing spinal inflammation and oxidative stress.
    Molecular pain, 2022, Volume: 18

    Topics: AMP-Activated Protein Kinases; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Chronic Pain

2022
Emodin alleviates lung ischemia-reperfusion injury by suppressing gasdermin D-mediated pyroptosis in rats.
    The clinical respiratory journal, 2023, Volume: 17, Issue:3

    Topics: Animals; Emodin; Gasdermins; Humans; Inflammation; Lung; Pyroptosis; Rats; Rats, Inbred Lew; Reperfu

2023
Emodin alleviates testicular ischemia-reperfusion injury through the inhibition of NLRP3-mediated pyroptosis.
    Tissue & cell, 2023, Volume: 82

    Topics: Animals; Emodin; Humans; Inflammation; Male; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Py

2023
Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway.
    PloS one, 2023, Volume: 18, Issue:7

    Topics: Animals; Constriction; Emodin; Hyperalgesia; Inflammation; Neuralgia; Peroxisome Proliferator-Activa

2023
Oral hydrogel nanoemulsion co-delivery system treats inflammatory bowel disease via anti-inflammatory and promoting intestinal mucosa repair.
    Journal of nanobiotechnology, 2023, Aug-18, Volume: 21, Issue:1

    Topics: Alginates; Anti-Inflammatory Agents; Curcumin; Emodin; Humans; Hydrogels; Inflammation; Inflammatory

2023
Emodin inhibits bladder inflammation and fibrosis in mice with interstitial cystitis by regulating JMJD3.
    Acta cirurgica brasileira, 2023, Volume: 38

    Topics: Animals; Cystitis; Cystitis, Interstitial; Emodin; Fibrosis; Humans; Inflammation; Mice

2023
Emodin relieved lipopolysaccharide-evoked inflammatory damage in WI-38 cells by up-regulating taurine up-regulated gene 1.
    BioFactors (Oxford, England), 2020, Volume: 46, Issue:5

    Topics: Apoptosis; Cell Line; Cell Survival; Chemokine CCL2; Emodin; Humans; Inflammation; Interleukin-6; Li

2020
Emodin improves alveolar hypercoagulation and inhibits pulmonary inflammation in LPS-provoked ARDS in mice via NF-κB inactivation.
    International immunopharmacology, 2020, Volume: 88

    Topics: Animals; Emodin; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Mice; NF-kappa B; Pu

2020
Optimal combination of anti-inflammatory components from Chinese medicinal formula Liang-Ge-San.
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drugs, Chinese Herbal; Emo

2021
Aloin protects mice from diet-induced non-alcoholic steatohepatitis via activation of Nrf2/HO-1 signaling.
    Food & function, 2021, Jan-21, Volume: 12, Issue:2

    Topics: Amino Acids; Animals; Apoptosis; Biomarkers; Choline Deficiency; Diet; Dietary Fats; Emodin; Gene Ex

2021
Aloin antagonizes stimulated ischemia/reperfusion-induced damage and inflammatory response in cardiomyocytes by activating the Nrf2/HO-1 defense pathway.
    Cell and tissue research, 2021, Volume: 384, Issue:3

    Topics: Animals; Cell Line; Emodin; Heme Oxygenase-1; Inflammation; Myocytes, Cardiac; NF-E2-Related Factor

2021
Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation.
    Aging, 2021, 05-29, Volume: 13, Issue:11

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Emodin; Gene Ontology; Genome; Inflamm

2021
Emodin inhibits lipid accumulation and inflammation in adipose tissue of high-fat diet-fed mice by inducing M2 polarization of adipose tissue macrophages.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:7

    Topics: 3T3-L1 Cells; Adipogenesis; Adipose Tissue; Animals; Cell Line; Diet, High-Fat; Emodin; Inflammation

2021
Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway.
    Journal of ethnopharmacology, 2021, Oct-28, Volume: 279

    Topics: Animals; Cassia; Diet, High-Fat; Dose-Response Relationship, Drug; Emodin; Glucose; Hepatocytes; Inf

2021
Chitosan functionalized graphene oxide nanocomposites for fluorescence imaging of apoptotic processes and targeted anti-inflammation study.
    Carbohydrate polymers, 2021, Oct-01, Volume: 269

    Topics: Animals; Anti-Inflammatory Agents; Antibodies; Apoptosis; Camptothecin; Cattle; Cell Line; Chitosan;

2021
Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Jan-01, Volume: 24

    Topics: A549 Cells; Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Cell Culture Techniques; Cyt

2018
Protein Kinase CK2: An Emerging Regulator of Immunity.
    Trends in immunology, 2018, Volume: 39, Issue:2

    Topics: Animals; Autoimmune Diseases; Casein Kinase II; Clinical Trials as Topic; Emodin; Humans; Immunity;

2018
Emodin alleviates alternatively activated macrophage and asthmatic airway inflammation in a murine asthma model.
    Acta pharmacologica Sinica, 2018, Volume: 39, Issue:8

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Emodin; Immunoglobulin E; Infl

2018
Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-κB.
    Molecules (Basel, Switzerland), 2018, Feb-26, Volume: 23, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Survival; Cyclooxygenase 2; Cytokines; Disease Mo

2018
Aurantio-obtusin, an anthraquinone from cassiae semen, ameliorates lung inflammatory responses.
    Phytotherapy research : PTR, 2018, Volume: 32, Issue:8

    Topics: A549 Cells; Animals; Anthraquinones; Cassia; Emodin; Glucosides; Humans; Inflammation; Lipopolysacch

2018
RETRACTED: Emodin attenuates apoptosis and inflammation induced by LPS through up-regulating lncRNA TUG1 in murine chondrogenic ATDC5 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Surviva

2018
Aloin suppresses lipopolysaccharide‑induced inflammation by inhibiting JAK1‑STAT1/3 activation and ROS production in RAW264.7 cells.
    International journal of molecular medicine, 2018, Volume: 42, Issue:4

    Topics: Animals; Emodin; Inflammation; Janus Kinase 1; Lipopolysaccharides; Mice; RAW 264.7 Cells; Reactive

2018
Emodin Attenuates Lipopolysaccharide-Induced Injury via Down-Regulation of miR-223 in H9c2 Cells.
    International heart journal, 2019, Mar-20, Volume: 60, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytoprotection; Down-Regulation; Emodin; Gene Expressi

2019
Emodin weakens liver inflammatory injury triggered by lipopolysaccharide through elevating microRNA-145 in vitro and in vivo.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Emodin; Female; Inflammation; Lipopolysa

2019
Emodin protects against lipopolysaccharide-induced inflammatory injury in HaCaT cells through upregulation of miR-21.
    Artificial cells, nanomedicine, and biotechnology, 2019, Volume: 47, Issue:1

    Topics: Apoptosis; Cell Line; Cell Survival; Cytoprotection; Emodin; Humans; Inflammation; Lipopolysaccharid

2019
Emodin reactivated autophagy and alleviated inflammatory lung injury in mice with lethal endotoxemia.
    Experimental animals, 2019, Nov-06, Volume: 68, Issue:4

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Autophagy; Disease Models, Animal; Emodin; End

2019
Emodin attenuates Alzheimer's disease by activating the protein kinase C signaling pathway.
    Cellular and molecular biology (Noisy-le-Grand, France), 2019, Jun-30, Volume: 65, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Behavior, Animal; Cell Survival; Cognition; Disea

2019
Emodin Alleviates the Airway Inflammation of Cough Variant Asthma in Mice by Regulating the Notch Pathway.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Jul-29, Volume: 25

    Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; Cough; Cytokines; Disease Models, Animal; Emodin; Eos

2019
[Effects of emodin on lipid accumulation and inflammation in hepatocytes].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019, Volume: 44, Issue:13

    Topics: Apolipoprotein B-100; Cells, Cultured; Emodin; Fatty Acid Synthase, Type I; Hepatocytes; Humans; Inf

2019
Effect of emodin on endoplasmic reticulum stress in rats with severe acute pancreatitis.
    Inflammation, 2013, Volume: 36, Issue:5

    Topics: Amylases; Animals; Carboxymethylcellulose Sodium; Emodin; Endoplasmic Reticulum Stress; Endoribonucl

2013
Emodin suppresses inflammatory responses and joint destruction in collagen-induced arthritic mice.
    Rheumatology (Oxford, England), 2013, Volume: 52, Issue:9

    Topics: Animals; Arthritis, Experimental; Emodin; Inflammation; Joints; Male; Mice; Mice, Inbred DBA; Mice,

2013
Emodin inhibits ATP-induced IL-1β secretion, ROS production and phagocytosis attenuation in rat peritoneal macrophages via antagonizing P2X₇ receptor.
    Pharmaceutical biology, 2014, Volume: 52, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Dose-Response Relationship, Drug; Emodin; Inflammation; In

2014
[Effect of emodin lipid nano-microbubble on MAPK signal pathway and inflammation cytokine in AT-II cells by mechanical stretch].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:6

    Topics: Animals; Blotting, Western; Cells, Cultured; Cytokines; Down-Regulation; Emodin; Epithelial Cells; E

2013
Anti-inflammatory and antioxidant effects of Aloe saponaria Haw in a model of UVB-induced paw sunburn in rats.
    Journal of photochemistry and photobiology. B, Biology, 2014, Apr-05, Volume: 133

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Chromatography, High Pressure Liquid; D

2014
Emodin inhibits LPS-induced inflammatory response by activating PPAR-γ in mouse mammary epithelial cells.
    International immunopharmacology, 2014, Volume: 21, Issue:2

    Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Emodin; Epithelial Cells; Female; Gene Expression Regula

2014
Emodin up-regulates glucose metabolism, decreases lipolysis, and attenuates inflammation in vitro.
    Journal of diabetes, 2015, Volume: 7, Issue:3

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Blotting, Western; Cells, Cultured; Electrophoretic Mobility Shif

2015
Emodin inhibits splenocyte proliferation and inflammation by modulating cytokine responses in a mouse model system.
    Journal of immunotoxicology, 2016, Volume: 13, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cathartics; Cell Proliferation; Cells, Cultured; Cytokines; Disea

2016
Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin.
    Molecular medicine reports, 2015, Volume: 11, Issue:6

    Topics: Animals; Cicatrix, Hypertrophic; Drugs, Chinese Herbal; Emodin; Female; Inflammation; Mice, Inbred C

2015
ω-Hydroxyemodin limits staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Cytokines; Emodin; Humans; In Vitro Techniques;

2015
Anti-inflammatory effect of emodin via attenuation of NLRP3 inflammasome activation.
    International journal of molecular sciences, 2015, Apr-10, Volume: 16, Issue:4

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Carrier Proteins; Emodin; Endotoxins; Inf

2015
Attenuation of Inflammation by Emodin in Lipopolysaccharide-induced Acute Kidney Injury via Inhibition of Toll-like Receptor 2 Signal Pathway.
    Iranian journal of kidney diseases, 2015, Volume: 9, Issue:3

    Topics: Acute Kidney Injury; Animals; Cells, Cultured; Emodin; Enzyme-Linked Immunosorbent Assay; Epithelial

2015
Emodin suppresses LPS-induced inflammation in RAW264.7 cells through a PPARγ-dependent pathway.
    International immunopharmacology, 2016, Volume: 34

    Topics: Aconitum; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Emodin; Humans; Inflammation; L

2016
Emodin Bidirectionally Modulates Macrophage Polarization and Epigenetically Regulates Macrophage Memory.
    The Journal of biological chemistry, 2016, May-27, Volume: 291, Issue:22

    Topics: Animals; Cell Polarity; Cells, Cultured; Emodin; Epigenomics; Humans; Immunologic Memory; Inflammati

2016
Emodin alleviates bleomycin-induced pulmonary fibrosis in rats.
    Toxicology letters, 2016, Nov-16, Volume: 262

    Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Differentiation;

2016
Emodin alleviates jejunum injury in rats with sepsis by inhibiting inflammation response.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Animals; Apoptosis; Calcitonin; Emodin; In Situ Nick-End Labeling; Inflammation; Interleukin-6; Inte

2016
Protective Effects of Emodin-Induced Neutrophil Apoptosis via the Ca
    BioMed research international, 2016, Volume: 2016

    Topics: Acrylates; Animals; Apoptosis; Calcium; Calpain; Caspase 12; Caspase 3; Emodin; Gene Expression Regu

2016
Inhibitory Effects of Emodin, Thymol, and Astragalin on Leptospira interrogans-Induced Inflammatory Response in the Uterine and Endometrium Epithelial Cells of Mice.
    Inflammation, 2017, Volume: 40, Issue:2

    Topics: Animals; Emodin; Endometrium; Epithelial Cells; Female; Inflammation; Kaempferols; Leptospira interr

2017
Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis.
    World journal of gastroenterology, 2017, Feb-28, Volume: 23, Issue:8

    Topics: Acute Disease; Alanine Transaminase; Animals; Anthraquinones; Aspartate Aminotransferases; Biphenyl

2017
Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells.
    British journal of pharmacology, 2010, Volume: 161, Issue:7

    Topics: Atherosclerosis; beta-Cyclodextrins; Cell Survival; Cells, Cultured; Cholesterol; Cytokines; Emodin;

2010
Emodin inhibits proinflammatory responses and inactivates histone deacetylase 1 in hypoxic rheumatoid synoviocytes.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:9

    Topics: Arthritis, Rheumatoid; Blotting, Western; Cell Proliferation; Cells, Cultured; Cytokines; Electropho

2011
Hepatoprotection of emodin and Polygonum multiflorum against CCl(4)-induced liver injury.
    Pharmaceutical biology, 2012, Volume: 50, Issue:3

    Topics: Animals; Disease Models, Animal; Emodin; Inflammation; Lipid Peroxidation; Liver Diseases; Liver Fun

2012
Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats.
    International journal of molecular sciences, 2012, Volume: 13, Issue:2

    Topics: Animals; Cell Survival; Diet, High-Fat; Emodin; Fatty Liver; Inflammation; Lipid Metabolism; Liver;

2012
Emodin inhibits tumor necrosis factor-α-induced migration and inflammatory responses in rat aortic smooth muscle cells.
    International journal of molecular medicine, 2012, Volume: 29, Issue:6

    Topics: Animals; Aorta; Cell Movement; Cell Proliferation; Cells, Cultured; Down-Regulation; Electrophoretic

2012
Emodin, a naturally occurring anthraquinone, ameliorates experimental autoimmune myocarditis in rats.
    The Tohoku journal of experimental medicine, 2012, Volume: 227, Issue:3

    Topics: Animals; Autoimmune Diseases; Body Weight; Emodin; Inflammation; Interleukin-1beta; Male; Myocarditi

2012
Emodin-6-O-β-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 52

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cecum; Cell Adhesion; Cell Movement; Cytoskeleton;

2013
Regulatory effects of emodin on NF-kappaB activation and inflammatory cytokine expression in RAW 264.7 macrophages.
    International journal of molecular medicine, 2005, Volume: 16, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Cell Line; Cell Nucleus; Emodin; I-kappa B Proteins; Inflam

2005
The effect of emodin-assisted early enteral nutrition on severe acute pancreatitis and secondary hepatic injury.
    Mediators of inflammation, 2007, Volume: 2007

    Topics: Acute Disease; Animals; Ascites; Cathartics; Edema; Emodin; Enteral Nutrition; Humans; Inflammation;

2007
Antiulcerogenic and anti-inflammatory effects of emodin, isolated from Rhamnus triquerta wall.
    Indian journal of experimental biology, 1991, Volume: 29, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Emodin; Female; Gastric Juice;

1991