emodin and Hypoxia
emodin has been researched along with Hypoxia in 3 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Emodin, a traditional Chinese medicinal herb widely used to treat acute hepatitis, has been reported to possess antioxidative capabilities and protective effects against myocardial ischemia/reperfusion injury." | 7.96 | Neuroprotective Effects of Emodin against Ischemia/Reperfusion Injury through Activating ERK-1/2 Signaling Pathway. ( Chang, CF; Chen, KY; Chen, YH; Chiang, YH; Kang, SJ; Lai, JH; Leung, SW; Tsai, YR; Wu, JC, 2020) |
| "This study explores the link between the antiproliferative activity of emodin through the generation of reactive oxygen species (ROS) in various cancer cell lines and the expression of the androgen receptor (AR) in the prostate cancer cell lines LNCaP (androgen-sensitive) and PC-3 (androgen-refractory), as well as the pro-metastatic low-density lipoprotein receptor-related protein 1 (LRP1) in the above prostate cancer cells and the nonprostate cell lines A549 (lung), HCT-15 (colon) and MG-63 (bone) under normoxic and hypoxia-like conditions." | 7.80 | Exploration of effects of emodin in selected cancer cell lines: enhanced growth inhibition by ascorbic acid and regulation of LRP1 and AR under hypoxia-like conditions. ( Iyer, VV; Masaldan, S, 2014) |
| "Emodin is a Chinese herbal anthraquinone used in several diseases." | 5.51 | Emodin protects H9c2 cells from hypoxia-induced injury by up-regulating miR-138 expression. ( Cai, S; Dai, H; Guan, J; Qin, Q; Zhang, X; Zhou, C, 2019) |
| " Emodin, a traditional Chinese medicinal herb widely used to treat acute hepatitis, has been reported to possess antioxidative capabilities and protective effects against myocardial ischemia/reperfusion injury." | 3.96 | Neuroprotective Effects of Emodin against Ischemia/Reperfusion Injury through Activating ERK-1/2 Signaling Pathway. ( Chang, CF; Chen, KY; Chen, YH; Chiang, YH; Kang, SJ; Lai, JH; Leung, SW; Tsai, YR; Wu, JC, 2020) |
| "This study explores the link between the antiproliferative activity of emodin through the generation of reactive oxygen species (ROS) in various cancer cell lines and the expression of the androgen receptor (AR) in the prostate cancer cell lines LNCaP (androgen-sensitive) and PC-3 (androgen-refractory), as well as the pro-metastatic low-density lipoprotein receptor-related protein 1 (LRP1) in the above prostate cancer cells and the nonprostate cell lines A549 (lung), HCT-15 (colon) and MG-63 (bone) under normoxic and hypoxia-like conditions." | 3.80 | Exploration of effects of emodin in selected cancer cell lines: enhanced growth inhibition by ascorbic acid and regulation of LRP1 and AR under hypoxia-like conditions. ( Iyer, VV; Masaldan, S, 2014) |
| "Emodin is a Chinese herbal anthraquinone used in several diseases." | 1.51 | Emodin protects H9c2 cells from hypoxia-induced injury by up-regulating miR-138 expression. ( Cai, S; Dai, H; Guan, J; Qin, Q; Zhang, X; Zhou, C, 2019) |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Leung, SW | 1 |
| Lai, JH | 1 |
| Wu, JC | 1 |
| Tsai, YR | 1 |
| Chen, YH | 1 |
| Kang, SJ | 1 |
| Chiang, YH | 1 |
| Chang, CF | 1 |
| Chen, KY | 1 |
| Zhang, X | 1 |
| Qin, Q | 1 |
| Dai, H | 1 |
| Cai, S | 1 |
| Zhou, C | 1 |
| Guan, J | 1 |
| Masaldan, S | 1 |
| Iyer, VV | 1 |
Other Studies
3 other studies available for emodin and Hypoxia
| Article | Year |
|---|---|
Neuroprotective Effects of Emodin against Ischemia/Reperfusion Injury through Activating ERK-1/2 Signaling Pathway.
Topics: Animals; Biomarkers; Cell Survival; Disease Susceptibility; Emodin; Hypoxia; Immunohistochemistry; M | 2020 |
Emodin protects H9c2 cells from hypoxia-induced injury by up-regulating miR-138 expression.
Topics: Animals; Cell Hypoxia; Cell Line; Cell Proliferation; Cell Survival; Emodin; Hypoxia; MicroRNAs; Myo | 2019 |
Exploration of effects of emodin in selected cancer cell lines: enhanced growth inhibition by ascorbic acid and regulation of LRP1 and AR under hypoxia-like conditions.
Topics: Ascorbic Acid; Cell Line, Tumor; Down-Regulation; Emodin; Gene Expression Regulation, Neoplastic; Hu | 2014 |