emodin has been researched along with Endotoxemia in 2 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Emodin is a major ingredient of Rheum Palmatum, a Chinese herb that is widely used in China for treatment of endotoxemia-related diseases." | 3.79 | Emodin improves lipopolysaccharide-induced microcirculatory disturbance in rat mesentery. ( Deng, JN; Dong, L; Duan, ML; Fan, JY; Han, JY; Li, A; Liu, YY; Sun, K; Wang, BE; Wang, MX, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, Y | 1 |
| Zhang, L | 1 |
| Jiang, Y | 1 |
| Dai, J | 1 |
| Tang, L | 1 |
| Liu, G | 1 |
| Li, A | 1 |
| Dong, L | 1 |
| Duan, ML | 1 |
| Sun, K | 1 |
| Liu, YY | 1 |
| Wang, MX | 1 |
| Deng, JN | 1 |
| Fan, JY | 1 |
| Wang, BE | 1 |
| Han, JY | 1 |
2 other studies available for emodin and Endotoxemia
| Article | Year |
|---|---|
Emodin reactivated autophagy and alleviated inflammatory lung injury in mice with lethal endotoxemia.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Autophagy; Disease Models, Animal; Emodin; End | 2019 |
Emodin improves lipopolysaccharide-induced microcirculatory disturbance in rat mesentery.
Topics: Animals; Emodin; Endotoxemia; Humans; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Male; | 2013 |