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emodin and ER-Negative PR-Negative HER2-Negative Breast Cancer

emodin has been researched along with ER-Negative PR-Negative HER2-Negative Breast Cancer in 5 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Research Excerpts

ExcerptRelevanceReference
"New targeted therapy for triple negative breast cancer (TNBC) is an urgent need, as advanced disease responds poorly to conventional chemotherapy."1.91Structure-based virtual screening of chemical libraries as potential MELK inhibitors and their therapeutic evaluation against breast cancer. ( Agarwal, P; Das, A; Karna, A; Lather, V; Pandita, D; Prajapati, A; Sharma, HK; Uppal, S, 2023)
"Emodin is an active anthraquinone derivative isolated from Rheum palmatum, with anticancer properties that have been reported to inhibit lung metastasis in a nude mouse xenograft model."1.48Emodin inhibits epithelial‑mesenchymal transition and metastasis of triple negative breast cancer via antagonism of CC‑chemokine ligand 5 secreted from adipocytes. ( Liu, S; Qin, Y; Song, X; Sun, Z; Wang, Y; Yang, J; Yu, K; Zhang, S; Zhou, X, 2018)
"Pretreatment with emodin significantly suppressed the TGF-β-induced EMT and cell migration in BT20 cells."1.46Stromal Fibroblasts from the Interface Zone of Triple Negative Breast Carcinomas Induced Epithelial-Mesenchymal Transition and its Inhibition by Emodin. ( Ho, CT; Hsu, HC; Hung, CM; Lin, YC; Liu, LC; Wang, HY; Way, TD, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Ayoub, AM1
Amin, MU1
Ambreen, G1
Dayyih, AA1
Abdelsalam, AM1
Somaida, A1
Engelhardt, K1
Wojcik, M1
Schäfer, J1
Bakowsky, U1
Das, A1
Prajapati, A1
Karna, A1
Sharma, HK1
Uppal, S1
Lather, V1
Pandita, D1
Agarwal, P1
McDonald, SJ1
Bullard, BM1
VanderVeen, BN1
Cardaci, TD1
Chatzistamou, I1
Fan, D1
Murphy, EA1
Song, X1
Zhou, X1
Qin, Y1
Yang, J1
Wang, Y1
Sun, Z1
Yu, K1
Zhang, S1
Liu, S1
Hsu, HC1
Liu, LC1
Wang, HY1
Hung, CM1
Lin, YC1
Ho, CT1
Way, TD1

Other Studies

5 other studies available for emodin and ER-Negative PR-Negative HER2-Negative Breast Cancer

ArticleYear
Photodynamic and antiangiogenic activities of parietin liposomes in triple negative breast cancer.
    Biomaterials advances, 2022, Volume: 134

    Topics: Angiogenesis Inhibitors; Cell Line, Tumor; Emodin; Humans; Liposomes; Photochemotherapy; Photosensit

2022
Structure-based virtual screening of chemical libraries as potential MELK inhibitors and their therapeutic evaluation against breast cancer.
    Chemico-biological interactions, 2023, May-01, Volume: 376

    Topics: Cell Line, Tumor; Cell Proliferation; Early Detection of Cancer; Emodin; Humans; Molecular Docking S

2023
Emodin reduces surgical wounding-accelerated tumor growth and metastasis via macrophage suppression in a murine triple-negative breast cancer model.
    Physiological reports, 2023, Volume: 11, Issue:19

    Topics: Animals; Cell Line, Tumor; Emodin; Humans; Lung; Lung Neoplasms; Macrophages; Mice; Triple Negative

2023
Emodin inhibits epithelial‑mesenchymal transition and metastasis of triple negative breast cancer via antagonism of CC‑chemokine ligand 5 secreted from adipocytes.
    International journal of molecular medicine, 2018, Volume: 42, Issue:1

    Topics: Adipocytes; Adult; Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cell Survival;

2018
Stromal Fibroblasts from the Interface Zone of Triple Negative Breast Carcinomas Induced Epithelial-Mesenchymal Transition and its Inhibition by Emodin.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Cancer-Associated Fibroblasts; Cell Line, Tumor; Emodin; Epithelial-Mesenchymal Transition; Female;

2017