Page last updated: 2024-10-26

emodin and Disease, Pulmonary

emodin has been researched along with Disease, Pulmonary in 4 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Research Excerpts

ExcerptRelevanceReference
"Pulmonary silicosis is characterized by lung fibrosis, which leads to impairment of pulmonary function; the specific mechanism remains to be fully elucidated Emodin shows antifibrotic effects in several organs with fibrosis, however, it has not been investigated in pulmonary silicosis."7.83Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact. ( Chen, M; Dang, X; Liu, Y; Pang, Y; Ren, H; Shang, D; Wang, J; Yang, T, 2016)
"Pulmonary silicosis is characterized by lung fibrosis, which leads to impairment of pulmonary function; the specific mechanism remains to be fully elucidated Emodin shows antifibrotic effects in several organs with fibrosis, however, it has not been investigated in pulmonary silicosis."3.83Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact. ( Chen, M; Dang, X; Liu, Y; Pang, Y; Ren, H; Shang, D; Wang, J; Yang, T, 2016)
"Emodin treatment abated the DEP-induced increase in airway resistance, and prevented the influx of neutrophils in bronchoalveolar lavage fluid."1.42Emodin mitigates diesel exhaust particles-induced increase in airway resistance, inflammation and oxidative stress in mice. ( Al-Salam, S; Ali, BH; Beegam, S; Nemmar, A; Yuvaraju, P, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lee, W1
Yang, S1
Lee, C1
Park, EK1
Kim, KM1
Ku, SK1
Bae, JS1
Chen, X1
Yang, Z1
Sun, R1
Mo, Z1
Jin, G1
Wei, F1
Hu, J1
Guan, W1
Zhong, N1
Nemmar, A1
Al-Salam, S1
Yuvaraju, P1
Beegam, S1
Ali, BH1
Yang, T1
Wang, J1
Pang, Y1
Dang, X1
Ren, H1
Liu, Y1
Chen, M1
Shang, D1

Other Studies

4 other studies available for emodin and Disease, Pulmonary

ArticleYear
Aloin reduces inflammatory gene iNOS via inhibition activity and p-STAT-1 and NF-κB.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2019, Volume: 126

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Emodin; Heme Oxygenase-1; Human Umbilical Vein

2019
Preparation of lung-targeting, emodin-loaded polylactic acid microspheres and their properties.
    International journal of molecular sciences, 2014, Apr-11, Volume: 15, Issue:4

    Topics: Animals; Drug Carriers; Emodin; Gelatin; Injections, Intravenous; Lactic Acid; Lung Diseases; Lung N

2014
Emodin mitigates diesel exhaust particles-induced increase in airway resistance, inflammation and oxidative stress in mice.
    Respiratory physiology & neurobiology, 2015, Aug-15, Volume: 215

    Topics: Airway Resistance; Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Emo

2015
Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact.
    Molecular medicine reports, 2016, Volume: 14, Issue:5

    Topics: Actins; Animals; Bronchoalveolar Lavage Fluid; Collagen Type I; Disease Models, Animal; Emodin; Enzy

2016