emodin has been researched along with Colonic Neoplasms in 15 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Colonic Neoplasms: Tumors or cancer of the COLON.
Excerpt | Relevance | Reference |
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"BACKGROUND Recently, colorectal cancer has become a more common type of tumor in the world." | 5.48 | Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Colorectal Cancer Cells. ( Cheng, C; Dong, W, 2018) |
"Emodin is a typical anthraquinone derivative from various plants that exhibits a wide spectrum of biological activities, such as anticancer, antibacterial, hepatoprotective and anti-inflammatory activities." | 2.82 | The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers. ( Chen, WW; Li, MY; Peng, W; Qian, D; Sun, X; Tang, DD; Wang, LY; Wu, CJ; Zhang, LL; Zhang, Q, 2022) |
" Optimal dosing of iv emodin and especially BTB 14431 for maximal efficacy remains unclear and should be a subject of further research." | 1.56 | Anti-tumorigenic Effects of Emodin and Its' Homologue BTB14431 on Vascularized Colonic Cancer in a Rat Model. ( Braumann, C; Dubiel, W; Freiburger, M; Höhn, P; Koplin, G; Luu, AM, 2020) |
"Emodin is an anthraquinone-active substance that has the ability to affect tumor progression." | 1.51 | Emodin Inhibits Colon Cancer Cell Invasion and Migration by Suppressing Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Pathway. ( Cui, CF; Gu, J; Jiang, XH; Wang, L; Yang, L, 2019) |
"BACKGROUND Recently, colorectal cancer has become a more common type of tumor in the world." | 1.48 | Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Colorectal Cancer Cells. ( Cheng, C; Dong, W, 2018) |
"Treatment with emodin reduced VEGFR phosphorylation, as evidenced by Western blot analysis." | 1.35 | The effect of emodin on VEGF receptors in human colon cancer cells. ( Lu, Y; Qian, J; Zhang, J, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (6.67) | 18.2507 |
2000's | 3 (20.00) | 29.6817 |
2010's | 9 (60.00) | 24.3611 |
2020's | 2 (13.33) | 2.80 |
Authors | Studies |
---|---|
Han, YM | 1 |
Lee, SK | 1 |
Jeong, DG | 1 |
Ryu, SE | 1 |
Han, DC | 1 |
Kim, DK | 1 |
Kwon, BM | 2 |
Sabbah, DA | 1 |
Simms, NA | 1 |
Brattain, MG | 1 |
Vennerstrom, JL | 1 |
Zhong, H | 1 |
Zhang, Q | 1 |
Chen, WW | 1 |
Sun, X | 1 |
Qian, D | 1 |
Tang, DD | 1 |
Zhang, LL | 1 |
Li, MY | 1 |
Wang, LY | 1 |
Wu, CJ | 1 |
Peng, W | 1 |
Höhn, P | 2 |
Braumann, C | 2 |
Freiburger, M | 1 |
Koplin, G | 2 |
Dubiel, W | 2 |
Luu, AM | 1 |
Geier, C | 1 |
Pohlenz, J | 1 |
Rogalla, S | 1 |
Wang, Y | 2 |
Luo, Q | 1 |
He, X | 1 |
Wei, H | 1 |
Wang, T | 1 |
Shao, J | 1 |
Jiang, X | 1 |
Gu, J | 1 |
Cui, CF | 1 |
Yang, L | 1 |
Wang, L | 1 |
Jiang, XH | 1 |
Cheng, C | 1 |
Dong, W | 1 |
Xie, MJ | 1 |
Ma, YH | 1 |
Miao, L | 1 |
Wang, HZ | 1 |
Xing, YY | 1 |
Xi, T | 1 |
Lu, YY | 1 |
Lee, KH | 1 |
Lee, MS | 1 |
Cha, EY | 1 |
Sul, JY | 1 |
Lee, JS | 1 |
Kim, JS | 1 |
Park, JB | 1 |
Kim, JY | 1 |
Yokohira, M | 1 |
Matsuda, Y | 1 |
Suzuki, S | 1 |
Hosokawa, K | 1 |
Yamakawa, K | 1 |
Hashimoto, N | 1 |
Saoo, K | 1 |
Nabae, K | 1 |
Doi, Y | 1 |
Kuno, T | 1 |
Imaida, K | 1 |
Ma, YS | 1 |
Weng, SW | 1 |
Lin, MW | 1 |
Lu, CC | 1 |
Chiang, JH | 1 |
Yang, JS | 1 |
Lai, KC | 1 |
Lin, JP | 1 |
Tang, NY | 1 |
Lin, JG | 1 |
Chung, JG | 1 |
Choi, SG | 1 |
Kim, J | 1 |
Sung, ND | 1 |
Son, KH | 1 |
Cheon, HG | 1 |
Kim, KR | 1 |
Lu, Y | 1 |
Zhang, J | 1 |
Qian, J | 1 |
Mereto, E | 1 |
Ghia, M | 1 |
Brambilla, G | 1 |
1 review available for emodin and Colonic Neoplasms
Article | Year |
---|---|
The versatile emodin: A natural easily acquired anthraquinone possesses promising anticancer properties against a variety of cancers.
Topics: Anthraquinones; Antineoplastic Agents; Apoptosis; Colonic Neoplasms; Emodin; Humans | 2022 |
14 other studies available for emodin and Colonic Neoplasms
Article | Year |
---|---|
Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity.
Topics: Anthraquinones; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Collagen; Colonic Neoplasms; | 2012 |
Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, D | 2012 |
Anti-tumorigenic Effects of Emodin and Its' Homologue BTB14431 on Vascularized Colonic Cancer in a Rat Model.
Topics: Animals; Apoptosis; Cell Proliferation; Colonic Neoplasms; Emodin; Female; Humans; Mice; Mice, Inbre | 2020 |
Dose-dependent role of novel agents emodin and BTB14431 in colonic cancer treatment in rats.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blood Cell Count; Colonic Neoplasms; Dise | 2017 |
Emodin Induces Apoptosis of Colon Cancer Cells via Induction of Autophagy in a ROS-Dependent Manner.
Topics: Apoptosis; Autophagy; Colonic Neoplasms; Emodin; Humans; Protein Kinase Inhibitors; Reactive Oxygen | 2018 |
Emodin Inhibits Colon Cancer Cell Invasion and Migration by Suppressing Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Pathway.
Topics: Animals; beta Catenin; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Emodin; Epithelial-Mesenc | 2019 |
Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Colorectal Cancer Cells.
Topics: Aloe; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Colorectal | 2018 |
Emodin-provoked oxidative stress induces apoptosis in human colon cancer HCT116 cells through a p53-mitochondrial apoptotic pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Colonic Neoplasms; Emodin; HCT116 Cells; Hu | 2014 |
Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Colon; Colonic Neop | 2017 |
Equivocal colonic carcinogenicity of Aloe arborescens Miller var. natalensis berger at high-dose level in a Wistar Hannover rat 2-y study.
Topics: Aloe; Animals; Colonic Neoplasms; Diarrhea; Disease Models, Animal; Emodin; Female; Glucosides; Male | 2009 |
Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Calcium; Caspase 3; Caspas | 2012 |
Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb.
Topics: cdc25 Phosphatases; Cell Cycle Proteins; Cell Line, Tumor; Colonic Neoplasms; Emodin; Enzyme Inhibit | 2007 |
The effect of emodin on VEGF receptors in human colon cancer cells.
Topics: Apoptosis; Blotting, Western; Colonic Neoplasms; Emodin; HCT116 Cells; Humans; Phosphorylation; Rece | 2008 |
Evaluation of the potential carcinogenic activity of Senna and Cascara glycosides for the rat colon.
Topics: Animals; Anthraquinones; Carcinogenicity Tests; Cathartics; Colon; Colonic Neoplasms; Emodin; Male; | 1996 |