emodin and Colitis
emodin has been researched along with Colitis in 4 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study evaluated the anti-inflammatory effects of aloe components (aloin, aloesin and aloe-gel) known to be biologically active in the rat model of colitis." | 7.77 | Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model. ( Kwon, HJ; Park, MY; Sung, MK, 2011) |
| "We aimed to further explore the mechanism of emodin in the treatment of ulcerative colitis from the perspective of metabolism and intestinal flora." | 4.12 | Emodin targeting the colonic metabolism via PPARγ alleviates UC by inhibiting facultative anaerobe. ( Chen, Y; Guo, S; He, J; Huang, B; Huang, S; Li, Y; Luo, S; Luo, X; Su, Y; Wang, X; Yang, G; Zhou, L, 2022) |
| " The present study evaluated the anti-inflammatory effects of aloe components (aloin, aloesin and aloe-gel) known to be biologically active in the rat model of colitis." | 3.77 | Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model. ( Kwon, HJ; Park, MY; Sung, MK, 2011) |
| "Colitis was evaluated by disease active index (DAI), colon length, inflammation response, and intestinal barrier function." | 1.72 | Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway. ( Fang, YX; Jiang, H; Liu, YQ; Shi, GF; Wang, Q; Yin, ZQ; Zhang, DJ; Zhang, J; Zheng, X, 2022) |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Luo, S | 2 |
| He, J | 1 |
| Huang, S | 2 |
| Wang, X | 2 |
| Su, Y | 1 |
| Li, Y | 2 |
| Chen, Y | 2 |
| Yang, G | 1 |
| Huang, B | 1 |
| Guo, S | 1 |
| Zhou, L | 2 |
| Luo, X | 2 |
| Jiang, H | 1 |
| Shi, GF | 1 |
| Fang, YX | 1 |
| Liu, YQ | 1 |
| Wang, Q | 2 |
| Zheng, X | 1 |
| Zhang, DJ | 1 |
| Zhang, J | 1 |
| Yin, ZQ | 1 |
| Xu, B | 1 |
| Chen, J | 1 |
| Park, MY | 1 |
| Kwon, HJ | 1 |
| Sung, MK | 1 |
Other Studies
4 other studies available for emodin and Colitis
| Article | Year |
|---|---|
Emodin targeting the colonic metabolism via PPARγ alleviates UC by inhibiting facultative anaerobe.
Topics: Animals; Caco-2 Cells; Chromatography, Liquid; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; | 2022 |
Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; | 2022 |
Synergistic effect of combined treatment with baicalin and emodin on DSS-induced colitis in mouse.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Emodin; Flavo | 2021 |
Dietary aloin, aloesin, or aloe-gel exerts anti-inflammatory activity in a rat colitis model.
Topics: Aloe; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromones; Colitis; Colon; Diet; Dietary Sup | 2011 |