emodin has been researched along with Colitis, Ulcerative in 8 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Colitis, Ulcerative: Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to further explore the mechanism of emodin in the treatment of ulcerative colitis from the perspective of metabolism and intestinal flora." | 4.12 | Emodin targeting the colonic metabolism via PPARγ alleviates UC by inhibiting facultative anaerobe. ( Chen, Y; Guo, S; He, J; Huang, B; Huang, S; Li, Y; Luo, S; Luo, X; Su, Y; Wang, X; Yang, G; Zhou, L, 2022) |
| "Emodin (EMO) is an active ingredient of Chinese traditional medicine with the potential to reportedly treat ulcerative colitis (UC)." | 1.72 | Dual-targeted colon-based integrated micelle drug delivery system for treatment of ulcerative colitis. ( Gu, M; Lu, L; Miao, Z; Ning, L; Xu, Y; Yan, J, 2022) |
| "Colitis was evaluated by disease active index (DAI), colon length, inflammation response, and intestinal barrier function." | 1.72 | Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway. ( Fang, YX; Jiang, H; Liu, YQ; Shi, GF; Wang, Q; Yin, ZQ; Zhang, DJ; Zhang, J; Zheng, X, 2022) |
| "Emodin is an anthraquinone compound derived from Rheum officinale Baill." | 1.48 | Emodin ameliorates ulcerative colitis by the flagellin-TLR5 dependent pathway in mice. ( Deng, X; Liu, Q; Luo, S; Luo, X; Pan, Z; Zhao, Z; Zhou, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 7 (87.50) | 2.80 |
| Authors | Studies |
|---|---|
| Pu, X | 1 |
| Ye, N | 1 |
| Lin, M | 1 |
| Chen, Q | 1 |
| Dong, L | 1 |
| Xu, H | 1 |
| Luo, R | 1 |
| Han, X | 1 |
| Qi, S | 1 |
| Nie, W | 1 |
| He, H | 1 |
| Wang, Y | 1 |
| Dai, L | 1 |
| Lin, D | 1 |
| Gao, F | 2 |
| Miao, Z | 1 |
| Gu, M | 1 |
| Yan, J | 1 |
| Lu, L | 1 |
| Xu, Y | 2 |
| Ning, L | 1 |
| Luo, S | 3 |
| He, J | 1 |
| Huang, S | 2 |
| Wang, X | 2 |
| Su, Y | 1 |
| Li, Y | 2 |
| Chen, Y | 2 |
| Yang, G | 1 |
| Huang, B | 1 |
| Guo, S | 1 |
| Zhou, L | 3 |
| Luo, X | 3 |
| Zhong, HY | 1 |
| Chen, KX | 1 |
| Dong, LL | 1 |
| Lin, MS | 1 |
| DU, HL | 1 |
| Jiang, H | 1 |
| Shi, GF | 1 |
| Fang, YX | 1 |
| Liu, YQ | 1 |
| Wang, Q | 2 |
| Zheng, X | 1 |
| Zhang, DJ | 1 |
| Zhang, J | 1 |
| Yin, ZQ | 1 |
| Wang, D | 1 |
| Sun, M | 1 |
| Zhang, Y | 1 |
| Chen, Z | 1 |
| Zang, S | 1 |
| Li, G | 2 |
| Clark, AR | 1 |
| Huang, J | 1 |
| Si, L | 1 |
| Xu, B | 1 |
| Chen, J | 1 |
| Deng, X | 1 |
| Liu, Q | 1 |
| Pan, Z | 1 |
| Zhao, Z | 1 |
8 other studies available for emodin and Colitis, Ulcerative
| Article | Year |
|---|---|
β-1,3-d-Glucan based yeast cell wall system loaded emodin with dual-targeting layers for ulcerative colitis treatment.
Topics: Animals; Anti-Inflammatory Agents; beta-Glucans; Caco-2 Cells; Cardiac Myosins; Cell Wall; Colitis, | 2021 |
Dual-targeted colon-based integrated micelle drug delivery system for treatment of ulcerative colitis.
Topics: Colitis, Ulcerative; Drug Delivery Systems; Emodin; Humans; Micelles | 2022 |
Emodin targeting the colonic metabolism via PPARγ alleviates UC by inhibiting facultative anaerobe.
Topics: Animals; Caco-2 Cells; Chromatography, Liquid; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; | 2022 |
[Mechanism of combined treatment of rhein and emodin in Rhubarb for ulcerative colitis].
Topics: Animals; Anthraquinones; Colitis, Ulcerative; Colon; Disease Models, Animal; Emodin; Interleukin-6; | 2022 |
Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; | 2022 |
Enhanced therapeutic efficacy of a novel colon-specific nanosystem loading emodin on DSS-induced experimental colitis.
Topics: Administration, Oral; Animals; Caco-2 Cells; Colitis, Ulcerative; Cyclooxygenase 2; Dextran Sulfate; | 2020 |
Synergistic effect of combined treatment with baicalin and emodin on DSS-induced colitis in mouse.
Topics: Animals; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Emodin; Flavo | 2021 |
Emodin ameliorates ulcerative colitis by the flagellin-TLR5 dependent pathway in mice.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Colitis, Ulcerative; Colon; Dextran Sulfate; Emodi | 2018 |