emodin has been researched along with Cicatrix, Hypertrophic in 4 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Cicatrix, Hypertrophic: An elevated scar, resembling a KELOID, but which does not spread into surrounding tissues. It is formed by enlargement and overgrowth of cicatricial tissue and regresses spontaneously.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with emodin significantly attenuated HS inflammation, as determined by histopathological assessment of the scar elevation index, collagen structure and inflammation (P<0." | 5.42 | Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin. ( Liu, C, 2015) |
| "Emodin has previously been reported to inhibit mechanical stress-induced HS inflammation." | 1.62 | Emodin alleviates hypertrophic scar formation by suppressing macrophage polarization and inhibiting the Notch and TGF-β pathways in macrophages. ( Cheng, Y; Deng, C; Hu, H; Li, W; Liu, C; Liu, Y; Qian, J; Qin, S; Wang, J; Xia, Z; Yang, S, 2021) |
| "Treatment with emodin significantly attenuated HS inflammation, as determined by histopathological assessment of the scar elevation index, collagen structure and inflammation (P<0." | 1.42 | Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin. ( Liu, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, Z | 1 |
| Wang, J | 1 |
| Yang, S | 1 |
| Liu, C | 2 |
| Qin, S | 1 |
| Li, W | 1 |
| Cheng, Y | 1 |
| Hu, H | 1 |
| Qian, J | 1 |
| Liu, Y | 1 |
| Deng, C | 1 |
| Wang, Q | 1 |
| Zhang, NN | 1 |
| Li, HY | 1 |
| Jiang, M | 1 |
| Gao, J | 1 |
| Bai, G | 1 |
| Tao, Y | 1 |
| Qu, Y | 1 |
4 other studies available for emodin and Cicatrix, Hypertrophic
| Article | Year |
|---|---|
Emodin alleviates hypertrophic scar formation by suppressing macrophage polarization and inhibiting the Notch and TGF-β pathways in macrophages.
Topics: Animals; Cicatrix, Hypertrophic; Emodin; Macrophages; Rats; Signal Transduction; Transforming Growth | 2021 |
[Active ingredients in rhubarb with anti-proliferative effects on scar fibroblasts].
Topics: Anthraquinones; Cell Cycle; Cell Proliferation; Cells, Cultured; Cicatrix, Hypertrophic; Drugs, Chin | 2012 |
Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin.
Topics: Animals; Cicatrix, Hypertrophic; Drugs, Chinese Herbal; Emodin; Female; Inflammation; Mice, Inbred C | 2015 |
[Influence of Emodin Gel on the Fibroblasts of Hypertrophic Scars in Rabbit Ear Model].
Topics: Animals; Cicatrix, Hypertrophic; Cytoplasm; Disease Models, Animal; Emodin; Fibroblasts; Gels; Hardn | 2015 |