emodin has been researched along with Cholestasis in 3 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof." | 7.75 | [Therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof: experiment with rats]. ( Ding, Y; Dong, HF; Dong, JH; Huang, ZH; Mei, H; Zhao, L, 2009) |
| "To investigate the therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof." | 3.75 | [Therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof: experiment with rats]. ( Ding, Y; Dong, HF; Dong, JH; Huang, ZH; Mei, H; Zhao, L, 2009) |
| " This study was designed to confirm the expected synergistic effects of RGHP at pharmacodynamic and pharmacokinetic levels." | 1.42 | Synergistic effects of rhubarb-gardenia herb pair in cholestatic rats at pharmacodynamic and pharmacokinetic levels. ( Dong, LC; Dong, X; Fan, YX; Li, HJ; Li, P; Ma, J; Yu, Q, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, LC | 1 |
| Fan, YX | 1 |
| Yu, Q | 1 |
| Ma, J | 1 |
| Dong, X | 1 |
| Li, P | 1 |
| Li, HJ | 1 |
| Ding, Y | 2 |
| Zhao, L | 2 |
| Mei, H | 2 |
| Zhang, SL | 1 |
| Huang, ZH | 2 |
| Duan, YY | 1 |
| Ye, P | 1 |
| Dong, HF | 1 |
| Dong, JH | 1 |
3 other studies available for emodin and Cholestasis
| Article | Year |
|---|---|
Synergistic effects of rhubarb-gardenia herb pair in cholestatic rats at pharmacodynamic and pharmacokinetic levels.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Anthraquinones; Aspar | 2015 |
Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway.
Topics: 1-Naphthylisothiocyanate; Animals; Anti-Inflammatory Agents; Cholestasis; Early Growth Response Prot | 2008 |
[Therapeutic effects of emodin on acute cholestatic hepatitis and mechanism thereof: experiment with rats].
Topics: Alanine Transaminase; Animals; Bilirubin; Chemokine CXCL1; Chemokine CXCL2; Cholestasis; Disease Mod | 2009 |