emodin has been researched along with Cholestasis, Intrahepatic in 6 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the expression of farnesoid X receptor (FXR) and the effect of emodin on FXR expression in a rat model of acute cholestatic hepatitis." | 7.80 | [Effect of emodin on expression of farnesoid X receptor in rats with acute cholestatic hepatitis]. ( Ding, Y; Li, HR; Xiong, XL; Xu, F, 2014) |
| "To investigate the expression of farnesoid X receptor (FXR) and the effect of emodin on FXR expression in a rat model of acute cholestatic hepatitis." | 3.80 | [Effect of emodin on expression of farnesoid X receptor in rats with acute cholestatic hepatitis]. ( Ding, Y; Li, HR; Xiong, XL; Xu, F, 2014) |
| "Emodin is an active ingredient in many herbal medicines and has a broad spectrum of pharmacological activities." | 1.51 | Paradoxical Effects of Emodin on ANIT-Induced Intrahepatic Cholestasis and Herb-Induced Hepatotoxicity in Mice. ( Bi, Y; Fan, G; Gao, X; Han, L; Li, C; Wang, X; Zhang, Y, 2019) |
| "Emodin has a protective effect on hepatocytes and a restoring activity on cholestatic hepatitis." | 1.36 | [Effect of emodin on P-gp expression in intrahepatic cholestatic rats]. ( Xu, H; Zhou, F, 2010) |
| "Emodin treatment can reduce the levels of TB, DB and ALT in ANIT induced-cholestatic hepatitis." | 1.35 | [Effect and mechanism of emodin on cholestatic hepatitis]. ( DING, Y; GAO, Y; HUANG, ZH; KANG, SX; MEI, H; PENG, HM; ZHAO, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Han, L | 1 |
| Bi, Y | 1 |
| Li, C | 1 |
| Gao, X | 1 |
| Fan, G | 1 |
| Zhang, Y | 1 |
| Ding, Y | 4 |
| Xu, F | 1 |
| Xiong, XL | 3 |
| Li, HR | 2 |
| Yan, SQ | 2 |
| Qin, H | 2 |
| Zhou, LS | 2 |
| Zhang, LL | 2 |
| Jiang, ZX | 2 |
| Chen, P | 1 |
| Yao, C | 1 |
| Zhao, L | 2 |
| MEI, H | 1 |
| PENG, HM | 1 |
| GAO, Y | 1 |
| HUANG, ZH | 1 |
| KANG, SX | 1 |
| Zhou, F | 1 |
| Xu, H | 1 |
6 other studies available for emodin and Cholestasis, Intrahepatic
| Article | Year |
|---|---|
Paradoxical Effects of Emodin on ANIT-Induced Intrahepatic Cholestasis and Herb-Induced Hepatotoxicity in Mice.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; AMP-Activated Protein Kinases; Animals; ATP Binding | 2019 |
[Effect of emodin on expression of farnesoid X receptor in rats with acute cholestatic hepatitis].
Topics: Acute Disease; Alanine Transaminase; Animals; Cholestasis, Intrahepatic; Disease Models, Animal; Emo | 2014 |
[Protective effect of emodin pretreatment in young rats with intrahepatic cholestasis].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Cholestasis, Intrahepatic; Dr | 2016 |
Preliminary study on Emodin alleviating alpha-naphthylisothiocyanate-induced intrahepatic cholestasis by regulation of liver farnesoid X receptor pathway.
Topics: 1-Naphthylisothiocyanate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Bin | 2016 |
[Effect and mechanism of emodin on cholestatic hepatitis].
Topics: 1-Naphthylisothiocyanate; Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; | 2009 |
[Effect of emodin on P-gp expression in intrahepatic cholestatic rats].
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransf | 2010 |