emodin has been researched along with Cardiotoxicity in 4 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aloe-emodin (AE), a novel ferroptosis inhibitor, alleviates the doxorubicin (DOX)-induced cardiotoxicity in H9c2 rat cardiomyocytes." | 8.31 | Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis. ( Cai, W; Fang, J; He, Y; Xi, J; Zhang, B, 2023) |
| "Emodin has the potential to attenuate DIC by directly binding to GSDMD to inhibit pyroptosis." | 5.91 | Emodin attenuates cardiomyocyte pyroptosis in doxorubicin-induced cardiotoxicity by directly binding to GSDMD. ( Chen, Y; Dai, S; Fan, X; Han, J; Huang, W; Huang, Z; Lin, J; Liu, Q; Su, L; Ye, B; Zhang, Y; Zhong, L, 2023) |
| "Aloe-emodin (AE), a novel ferroptosis inhibitor, alleviates the doxorubicin (DOX)-induced cardiotoxicity in H9c2 rat cardiomyocytes." | 4.31 | Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis. ( Cai, W; Fang, J; He, Y; Xi, J; Zhang, B, 2023) |
| "Emodin has the potential to attenuate DIC by directly binding to GSDMD to inhibit pyroptosis." | 1.91 | Emodin attenuates cardiomyocyte pyroptosis in doxorubicin-induced cardiotoxicity by directly binding to GSDMD. ( Chen, Y; Dai, S; Fan, X; Han, J; Huang, W; Huang, Z; Lin, J; Liu, Q; Su, L; Ye, B; Zhang, Y; Zhong, L, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, Y | 1 |
| Xi, J | 1 |
| Fang, J | 1 |
| Zhang, B | 1 |
| Cai, W | 1 |
| Dai, S | 1 |
| Chen, Y | 1 |
| Fan, X | 1 |
| Han, J | 1 |
| Zhong, L | 1 |
| Zhang, Y | 1 |
| Liu, Q | 1 |
| Lin, J | 1 |
| Huang, W | 1 |
| Su, L | 1 |
| Huang, Z | 1 |
| Ye, B | 1 |
| Birari, L | 1 |
| Wagh, S | 1 |
| Patil, KR | 1 |
| Mahajan, UB | 1 |
| Unger, B | 1 |
| Belemkar, S | 1 |
| Goyal, SN | 1 |
| Ojha, S | 1 |
| Patil, CR | 1 |
| Esmat, AY | 1 |
| Said, MM | 1 |
| Khalil, SA | 1 |
4 other studies available for emodin and Cardiotoxicity
| Article | Year |
|---|---|
Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis.
Topics: Aloe; Animals; Cardiotoxicity; Cell Line; Doxorubicin; Emodin; Ferroptosis; Myocytes, Cardiac; NF-E2 | 2023 |
Emodin attenuates cardiomyocyte pyroptosis in doxorubicin-induced cardiotoxicity by directly binding to GSDMD.
Topics: Animals; Cardiotoxicity; Doxorubicin; Emodin; Mice; Myocytes, Cardiac; Pyroptosis | 2023 |
Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines.
Topics: Animals; Antibiotics, Antineoplastic; Cardiotoxicity; Cathartics; Cytokines; Doxorubicin; Emodin; In | 2020 |
Aloin: a natural antitumor anthraquinone glycoside with iron chelating and non-atherogenic activities.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cardiotoxicity; Doxorubicin; Emodin; Glycosides; Heart; | 2015 |