emodin has been researched along with Carcinoma in 9 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study has evaluated the Emodin efficacy on the Akt, MAPK, ERK and DNMT expression pattern during 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinoma in golden Syrian hamsters, in order to explore its antitumor potential." | 7.83 | EMODIN EFFICACY ON THE AKT, MAPK, ERK AND DNMT EXPRESSION PATTERN DURING DMBA-INDUCED ORAL CARCINOMA IN GOLDEN SYRIAN HAMSTERS. ( Manimaran, A; Manoharan, S; Neelakandan, M, 2016) |
| "Emodin is a natural anthraquinone derivative isolated from the Rheum palmatum." | 5.46 | Emodin suppresses the nasopharyngeal carcinoma cells by targeting the chloride channels. ( Chen, L; Liu, M; Ma, L; Wang, L; Yang, H; Yang, Y; Yin, Z; Zhu, L, 2017) |
| "Emodin is an active anthraquinone that has been reported to have diverse biological effects." | 5.39 | Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes. ( Chan, RY; Chan, SW; Li, WY; Yu, PH, 2013) |
| "The present study has evaluated the Emodin efficacy on the Akt, MAPK, ERK and DNMT expression pattern during 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinoma in golden Syrian hamsters, in order to explore its antitumor potential." | 3.83 | EMODIN EFFICACY ON THE AKT, MAPK, ERK AND DNMT EXPRESSION PATTERN DURING DMBA-INDUCED ORAL CARCINOMA IN GOLDEN SYRIAN HAMSTERS. ( Manimaran, A; Manoharan, S; Neelakandan, M, 2016) |
| "Emodin is a natural anthraquinone derivative isolated from the Rheum palmatum." | 1.46 | Emodin suppresses the nasopharyngeal carcinoma cells by targeting the chloride channels. ( Chen, L; Liu, M; Ma, L; Wang, L; Yang, H; Yang, Y; Yin, Z; Zhu, L, 2017) |
| "Emodin is an active anthraquinone that has been reported to have diverse biological effects." | 1.39 | Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes. ( Chan, RY; Chan, SW; Li, WY; Yu, PH, 2013) |
| "In a model of dimethylhydrazine-induced colorectal tumors in male mice aloin- or sennoside-enriched diets (0." | 1.29 | Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice. ( Baretton, G; Siegers, CP; Siemers, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, L | 1 |
| Yang, Y | 1 |
| Yin, Z | 1 |
| Liu, M | 1 |
| Wang, L | 1 |
| Chen, L | 1 |
| Zhu, L | 1 |
| Yang, H | 1 |
| Manimaran, A | 1 |
| Manoharan, S | 1 |
| Neelakandan, M | 1 |
| Li, WY | 1 |
| Chan, RY | 1 |
| Yu, PH | 1 |
| Chan, SW | 1 |
| Tang, SH | 1 |
| Huang, HS | 1 |
| Wu, HU | 1 |
| Tsai, YT | 1 |
| Chuang, MJ | 1 |
| Yu, CP | 1 |
| Huang, SM | 1 |
| Sun, GH | 1 |
| Chang, SY | 1 |
| Hsiao, PW | 1 |
| Yu, DS | 1 |
| Cha, TL | 1 |
| Wang, QJ | 1 |
| Cai, XB | 1 |
| Liu, MH | 1 |
| Hu, H | 1 |
| Tan, XJ | 1 |
| Jing, XB | 1 |
| Li, XX | 1 |
| Dong, Y | 1 |
| Wang, W | 1 |
| Wang, HL | 1 |
| Chen, YY | 1 |
| Shi, GY | 1 |
| Yi, J | 2 |
| Wang, J | 2 |
| Nićiforović, A | 1 |
| Adzić, M | 1 |
| Spasić, SD | 1 |
| Radojcić, MB | 1 |
| Cai, J | 1 |
| Niu, X | 1 |
| Chen, Y | 1 |
| Hu, Q | 1 |
| Shi, G | 1 |
| Wu, H | 1 |
| Siegers, CP | 1 |
| Siemers, J | 1 |
| Baretton, G | 1 |
9 other studies available for emodin and Carcinoma
| Article | Year |
|---|---|
Emodin suppresses the nasopharyngeal carcinoma cells by targeting the chloride channels.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Count; Cell Cycle; Cell Cycle Checkpoints; Cell Li | 2017 |
EMODIN EFFICACY ON THE AKT, MAPK, ERK AND DNMT EXPRESSION PATTERN DURING DMBA-INDUCED ORAL CARCINOMA IN GOLDEN SYRIAN HAMSTERS.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Prolife | 2016 |
Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Carci | 2013 |
Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Growth Processes; Cell Line, Tumor; Down- | 2014 |
Apoptosis induced by emodin is associated with alterations of intracellular acidification and reactive oxygen species in EC-109 cells.
Topics: Acids; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation | 2010 |
Emodin as an effective agent in targeting cancer stem-like side population cells of gallbladder carcinoma.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette | 2013 |
Antitumor effects of a natural anthracycline analog (Aloin) involve altered activity of antioxidant enzymes in HeLaS3 cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Cell Cycle; Cell Proliferation; Emodin; Female; HeLa Ce | 2007 |
Emodin-induced generation of reactive oxygen species inhibits RhoA activation to sensitize gastric carcinoma cells to anoikis.
Topics: Acetylcysteine; Actins; Anoikis; Arsenic Trioxide; Arsenicals; Carcinoma; Cell Line, Tumor; Emodin; | 2008 |
Sennosides and aloin do not promote dimethylhydrazine-induced colorectal tumors in mice.
Topics: 1,2-Dimethylhydrazine; Adenoma; Aloe; Animals; Anthraquinones; Carcinogens; Carcinoma; Cathartics; C | 1993 |