emodin has been researched along with Carcinoma, Squamous Cell in 9 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study is to focus the chemopreventive potential of Emodin during 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis." | 7.88 | Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach. ( Manimaran, A; Manoharan, S, 2018) |
| " The PCNA, cyclin D1, CDK4, CDK6 and survivin expression in the buccal mucosa was utilized to evaluate the Emodin efficacy on abnormal cell proliferation during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis in golden Syrian hamsters." | 7.85 | EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS. ( Buddhan, R; Manimaran, A; Manoharan, S, 2017) |
| "The aim of the present study is to focus the chemopreventive potential of Emodin during 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis." | 3.88 | Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach. ( Manimaran, A; Manoharan, S, 2018) |
| " The PCNA, cyclin D1, CDK4, CDK6 and survivin expression in the buccal mucosa was utilized to evaluate the Emodin efficacy on abnormal cell proliferation during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis in golden Syrian hamsters." | 3.85 | EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS. ( Buddhan, R; Manimaran, A; Manoharan, S, 2017) |
| "Emodin can inhibit the proliferation of Tca8113 cells and affect their cell cycle distribution possibly by inhibiting the signaling pathways of cell cycle regulation." | 1.42 | [Effect of emodin on proliferation and cell cycle of human oral squamous carcinoma Tca8113 cells in vitro]. ( Jiao, K; Li, J; Wu, F; Yu, Z; Zhang, K; Zhu, Y, 2015) |
| "Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer deaths worldwide." | 1.40 | Emodin represses TWIST1-induced epithelial-mesenchymal transitions in head and neck squamous cell carcinoma cells by inhibiting the β-catenin and Akt pathways. ( Chou, CH; Ho, CT; Huang, CH; Huang, JT; Way, TD; Yang, MH, 2014) |
| "Emodin was isolated from Rheum palmatum L." | 1.35 | Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways. ( Chen, GW; Chung, JG; Fan, MJ; Ho, CC; Lai, WW; Lin, ML; Lin, SY; Liu, KC; Wu, PP; Yang, JS; Yu, FS, 2009) |
| "Aloe-emodin-treated CH27 cells had an increased relative abundance of cytochrome c in the cytosolic fraction." | 1.31 | Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma. ( Hsu, SL; Lee, HZ; Liu, MC; Wu, CH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Nowak-Perlak, M | 1 |
| Bromke, MA | 1 |
| Ziółkowski, P | 1 |
| Woźniak, M | 1 |
| Manimaran, A | 2 |
| Buddhan, R | 1 |
| Manoharan, S | 2 |
| Way, TD | 1 |
| Huang, JT | 1 |
| Chou, CH | 1 |
| Huang, CH | 1 |
| Yang, MH | 1 |
| Ho, CT | 1 |
| Zhang, K | 1 |
| Jiao, K | 1 |
| Zhu, Y | 1 |
| Wu, F | 1 |
| Li, J | 1 |
| Yu, Z | 1 |
| Liu, MD | 1 |
| Xiong, SJ | 1 |
| Tan, F | 1 |
| Liu, Y | 1 |
| Lin, SY | 1 |
| Lai, WW | 1 |
| Ho, CC | 1 |
| Yu, FS | 1 |
| Chen, GW | 1 |
| Yang, JS | 1 |
| Liu, KC | 1 |
| Lin, ML | 1 |
| Wu, PP | 1 |
| Fan, MJ | 1 |
| Chung, JG | 1 |
| Lee, HZ | 2 |
| Hsu, SL | 1 |
| Liu, MC | 1 |
| Wu, CH | 1 |
9 other studies available for emodin and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
The Comparison of the Efficiency of Emodin and Aloe-Emodin in Photodynamic Therapy.
Topics: Aloe; Anthraquinones; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Emodin; Humans; Melanom | 2022 |
EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Carcinogen | 2017 |
Emodin represses TWIST1-induced epithelial-mesenchymal transitions in head and neck squamous cell carcinoma cells by inhibiting the β-catenin and Akt pathways.
Topics: Animals; beta Catenin; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; | 2014 |
[Effect of emodin on proliferation and cell cycle of human oral squamous carcinoma Tca8113 cells in vitro].
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin E; Cyclin-Depende | 2015 |
Physcion 8-O-β-glucopyranoside induces mitochondria-dependent apoptosis of human oral squamous cell carcinoma cells via suppressing survivin expression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; E | 2016 |
Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Squamo | 2018 |
Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways.
Topics: Apoptosis; Calcium; Carcinoma, Squamous Cell; Caspase 3; Caspase 9; CDC2 Protein Kinase; Cell Divisi | 2009 |
Effects and mechanisms of emodin on cell death in human lung squamous cell carcinoma.
Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Ca | 2001 |
Effects and mechanisms of aloe-emodin on cell death in human lung squamous cell carcinoma.
Topics: Anthraquinones; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Caspases; Cytochrome c G | 2001 |