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emodin and Carcinoma, Merkel Cell

emodin has been researched along with Carcinoma, Merkel Cell in 1 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Carcinoma, Merkel Cell: A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)

Research Excerpts

ExcerptRelevanceReference
"Aloe emodin has been reported to be nontoxic for normal cells but to possess specific toxicity for neuroectodermal tumor cells."1.31The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line. ( Avigad, S; Beery, E; Fenig, E; Nordenberg, J; Wasserman, L, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wasserman, L1
Avigad, S1
Beery, E1
Nordenberg, J1
Fenig, E1

Other Studies

1 other study available for emodin and Carcinoma, Merkel Cell

ArticleYear
The effect of aloe emodin on the proliferation of a new merkel carcinoma cell line.
    The American Journal of dermatopathology, 2002, Volume: 24, Issue:1

    Topics: Aged; Anthraquinones; Antineoplastic Agents; Biomarkers, Tumor; Butyrates; Carcinoma, Merkel Cell; C

2002