emodin has been researched along with Carcinogenesis in 6 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis." | 7.91 | Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019) |
| "The aim of the present study is to focus the chemopreventive potential of Emodin during 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis." | 7.88 | Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach. ( Manimaran, A; Manoharan, S, 2018) |
| " The PCNA, cyclin D1, CDK4, CDK6 and survivin expression in the buccal mucosa was utilized to evaluate the Emodin efficacy on abnormal cell proliferation during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis in golden Syrian hamsters." | 7.85 | EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS. ( Buddhan, R; Manimaran, A; Manoharan, S, 2017) |
| "Lung adenocarcinoma is the most common type of lung cancer." | 5.91 | The ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway. ( Han, X; Li, H; Lv, C; Wang, L; Wang, M, 2023) |
| "Treatment of HER-2-overexpressing breast cancer cells with AE reduced tumor initiation, cell migration, and cell invasion." | 5.43 | Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells. ( Ho, CT; Hung, CM; Kao, JY; Lin, YC; Ma, JW; Way, TD, 2016) |
| "This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis." | 3.91 | Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019) |
| "The aim of the present study is to focus the chemopreventive potential of Emodin during 7,12-dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis." | 3.88 | Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach. ( Manimaran, A; Manoharan, S, 2018) |
| " The PCNA, cyclin D1, CDK4, CDK6 and survivin expression in the buccal mucosa was utilized to evaluate the Emodin efficacy on abnormal cell proliferation during 7,12-dimethylbenz(a)anthracene (DMBA) induced oral carcinogenesis in golden Syrian hamsters." | 3.85 | EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS. ( Buddhan, R; Manimaran, A; Manoharan, S, 2017) |
| "Lung adenocarcinoma is the most common type of lung cancer." | 1.91 | The ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway. ( Han, X; Li, H; Lv, C; Wang, L; Wang, M, 2023) |
| "Moreover, DEAS genes related to the two colorectal cancerous pathways, Wnt and Notch pathways, were annotated." | 1.56 | Post-transcriptional regulation activity through alternative splicing involved in the effects of Aloe vera on the Wnt/β-catenin and Notch pathways in colorectal cancer cells. ( Li, Y; Peng, C; Shen, X; Yao, M; Yuan, Y; Zhang, W, 2020) |
| "Treatment of HER-2-overexpressing breast cancer cells with AE reduced tumor initiation, cell migration, and cell invasion." | 1.43 | Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells. ( Ho, CT; Hung, CM; Kao, JY; Lin, YC; Ma, JW; Way, TD, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, L | 1 |
| Han, X | 1 |
| Li, H | 1 |
| Lv, C | 1 |
| Wang, M | 2 |
| Peng, C | 1 |
| Zhang, W | 2 |
| Shen, X | 1 |
| Yuan, Y | 1 |
| Li, Y | 1 |
| Yao, M | 1 |
| Manimaran, A | 2 |
| Buddhan, R | 1 |
| Manoharan, S | 2 |
| Li, Z | 1 |
| Lin, Y | 1 |
| Zhang, S | 1 |
| Zhou, L | 1 |
| Yan, G | 1 |
| Wang, Y | 1 |
| Zhang, M | 1 |
| Lin, H | 1 |
| Tong, Q | 1 |
| Duan, Y | 1 |
| Du, G | 1 |
| Ma, JW | 1 |
| Hung, CM | 1 |
| Lin, YC | 1 |
| Ho, CT | 1 |
| Kao, JY | 1 |
| Way, TD | 1 |
6 other studies available for emodin and Carcinogenesis
| Article | Year |
|---|---|
The ethyl acetate extract of Wenxia Changfu Formula inhibits the carcinogenesis of lung adenocarcinoma by regulating PI3K-AKT signaling pathway.
Topics: Adenocarcinoma of Lung; Carcinogenesis; Emodin; Humans; Lung Neoplasms; Matrix Metalloproteinase 3; | 2023 |
Post-transcriptional regulation activity through alternative splicing involved in the effects of Aloe vera on the Wnt/β-catenin and Notch pathways in colorectal cancer cells.
Topics: Aloe; Alternative Splicing; beta Catenin; Carcinogenesis; Cell Line, Tumor; Chromones; Colorectal Ne | 2020 |
EMODIN DOWNREGULATES CELL PROLIFERATION MARKERS DURING DMBA INDUCED ORAL CARCINOGENESIS IN GOLDEN SYRIAN HAMSTERS.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Carcinogen | 2017 |
Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis.
Topics: Allografts; Animals; Blood Coagulation Disorders; Carcinogenesis; Carcinoma, Lewis Lung; Emodin; Ext | 2019 |
Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells.
Topics: Anthraquinones; Breast Neoplasms; Carcinogenesis; Cell Movement; Down-Regulation; Emodin; Female; Gl | 2016 |
Tumor Preventive Efficacy of Emodin in 7,12-Dimethylbenz[a]Anthracene-Induced Oral Carcinogenesis: a Histopathological and Biochemical Approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Squamo | 2018 |