emodin and Cancer of Liver

emodin has been researched along with Cancer of Liver in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (18.18)29.6817
2010's24 (54.55)24.3611
2020's12 (27.27)2.80

Authors

AuthorsStudies
Brenes, R; Miller, DL; Nguyen, LMN; Rohde, ML1
He, C; Shi, Y; Wang, Y; Yang, J; Zhao, H; Zhu, X1
Chen, HL; Huang, Y; Lu, SF; Lu, Y; Wu, L; Xing, ML; Yang, FR; Yang, QW; Zhang, YT1
Chen, X; Shen, G; Yin, J; Zhao, X1
Gu, W; Peng, G; Qin, B; Shangwen, J; Tang, Y; Wang, Q; Wang, S; Wu, Y; Xu, J; Ye, ZJ; Zeng, Z1
Huang, Y; Li, C; Liu, Y; Lu, P; Wu, W; Zhu, Z1
Dai, X; Gao, R; Ning, H; Wang, M; Xu, H; Yu, B; Zhu, Y1
Ali, M; Bhardwaj, SK; Chaudhary, A; Haque, R; Khan, A; Sinha, KK; Srivastava, A1
Chen, X; Deng, H; Lai, Q; Leng, Y; Wang, H; Xiong, Z; Yang, M1
Ma, C; Miao, W; Sun, R; Zhai, R1
Bai, Y; Feng, H; Feng, J; Jia, W; Jiang, Y; Khan, H; Song, H; Yang, B; Yu, Z; Zaib, T1
Alanazy, M; Dewdney, B; George, J; Gillman, R; Hebbard, L; Qiao, L; Roberts, A; Walker, S; Wankell, M1
Guo, R; Jiang, Y; Liu, T; Lv, R; Ming, H; Tian, X; Wang, Q; Wei, H1
Huang, LH; Li, Y; Pan, XP; Wang, C1
Dong, H; Gao, M; Li, Q; Pang, Y; Tian, Y; Wang, J; Wu, G; Xu, H; Zhang, B; Zhang, C; Zhang, H1
Li, N; Wang, C; You, S; Zhang, P1
Dong, X; Fu, J; Leng, X; Liang, X; Ni, B; Ni, J; Yin, X; You, L1
Kan, SY; Kang, H; Kim, BM; Kim, GH; Kim, JH; Kim, YS; Lee, YM; Lim, JH; Oh, TI; Shin, DH; Yim, WJ1
Li, Y; Pan, X; Wang, C; Zhang, T; Zhu, L1
Liu, JW; Sun, QF; Tang, Y; Wang, XW; Ye, ZJ; Zhou, DH; Zhou, RS1
Gao, S; Jin, GZ; Li, C; Sun, S; Yang, WS1
Bist, P; Hui, KM; Kumar, AP; Lim, LH; Manu, KA; Ong, TH; Perumal, E; Samy, RP; Sethi, G; Shanmugam, MK; Siveen, KS; Subramaniam, A1
Chen, G; Hu, SM; Ke, SD; Qiu, H; Yu, SY; Zou, SQ1
Ahn, KS; Hui, KM; Kumar, AP; Li, F; Loo, SY; Manu, KA; Park, JI; Perumal, E; Rajendran, P; Sethi, G; Shanmugam, MK; Siveen, KS; Subramaniam, A1
Abbasi, T; Ahn, KS; Chen, L; Hui, KM; Kapoor, S; Kumar, AP; Li, F; Ong, TH; Perumal, E; Sethi, G; Shanmugam, MK; Subramaniam, A; Vali, S1
Chen, Y; Zhang, T; Zhang, X; Zhang, Y1
Deng, S; Gao, M; Guan, X; Liu, H; Lv, L; Tian, Y; Xu, H; Zhang, C1
He, Y; Huang, J; Li, S; Liu, W; Shen, X; Suksamrarn, A; Wang, F; Wang, P; Yang, L; Zhang, G1
Cui, Y; Liu, Q; Liu, X; Lu, P; Song, G; Zhu, D1
Cao, Q; Chen, Y; Lin, W; Ling, C; Wang, C; Yin, H; Zhong, M1
Guo, P; Qin, F; Wang, Q; Wang, Y; Xing, Y; Yan, Y; Zhang, J; Zhuang, J1
Deng, S; Gao, D; Gao, M; Gao, X; Liu, H; Lv, L; Ma, C; Tian, Y; Wang, C; Xu, H; Zhang, C1
Hsu, CM; Hsu, YA; Huang, SH; Shieh, FK; Tsai, FJ; Tsai, Y; Wan, L1
Alisi, A; Balsano, C; Ghidinelli, M; Missale, G; Zerbini, A1
Jeon, W; Jeon, YK; Nam, MJ1
Lu, Y; Shan, W; Wang, T; Xiong, S; Yin, X1
Goto, T; Nagashima, H; Nakamura, K1
Gao, XG; Li, KZ; Lian, T; Liu, JB; Zhao, AZ1
Chen, YY; Chiang, LC; Lin, CC; Shieh, DE; Yen, MH1
Gu, LQ; Wang, XD; Wu, JY1
Chung, MC; Lu, GD; Ong, CN; Shen, HM1
Kim, HR; Kim, J; Kim, K; Kim, SJ; Lee, KH1
Lin, SZ; Xu, XC1

Reviews

1 review(s) available for emodin and Cancer of Liver

ArticleYear
[Experimental advance of applying emodin for prevention and treatment of liver diseases].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2008, Volume: 28, Issue:1

    Topics: Animals; Apoptosis; Cell Line, Tumor; Emodin; Humans; Liver Cirrhosis; Liver Neoplasms; Protective Agents

2008

Other Studies

43 other study(ies) available for emodin and Cancer of Liver

ArticleYear
HEPATOCELLULAR TOXICITY OF THE METABOLITE EMODIN PRODUCED BY THE COMMON BUCKTHORN (RHAMNUS CATHARTICA) IN GREEN FROG (LITHOBATES CLAMITANS) TADPOLES.
    Journal of wildlife diseases, 2022, 04-01, Volume: 58, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Emodin; Fibrosis; Larva; Liver Neoplasms; Rana clamitans; Rhamnus

2022
Automatic Segmentation of Magnetic Resonance Images of Severe Patients with Advanced Liver Cancer and the Molecular Mechanism of Emodin-Induced Apoptosis of HepG2 Cells under the Deep Learning.
    Journal of healthcare engineering, 2022, Volume: 2022

    Topics: Apoptosis; Deep Learning; Emodin; Hep G2 Cells; Humans; Image Processing, Computer-Assisted; Liver Neoplasms; Magnetic Resonance Imaging

2022
Multi-material basis and multi-mechanisms of the Dahuang Zhechong pill for regulating Treg/Th1 balance in hepatocellular carcinoma.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 100

    Topics: Animals; Carcinoma, Hepatocellular; Drugs, Chinese Herbal; Emodin; Glutamine; Liver Neoplasms; Mice; T-Lymphocytes, Regulatory; Tandem Mass Spectrometry; Transforming Growth Factor beta; Tumor Microenvironment

2022
Emodin suppresses hepatocellular carcinoma growth by regulating macrophage polarization via microRNA-26a/transforming growth factor beta 1/protein kinase B.
    Bioengineered, 2022, Volume: 13, Issue:4

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Emodin; Humans; Liver Neoplasms; Macrophages; MicroRNAs; Proto-Oncogene Proteins c-akt; Transforming Growth Factor beta; Transforming Growth Factor beta1

2022
Emodin inhibits invasion and migration of hepatocellular carcinoma cells via regulating autophagy-mediated degradation of snail and β-catenin.
    BMC cancer, 2022, Jun-18, Volume: 22, Issue:1

    Topics: Autophagy; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Emodin; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2022
Emodin regulates the autophagy via the miR-371a-5p/PTEN axis to inhibit hepatic malignancy.
    Biochemical and biophysical research communications, 2022, 09-03, Volume: 619

    Topics: Autophagy; Cell Proliferation; Emodin; Humans; Liver Neoplasms; MicroRNAs; PTEN Phosphohydrolase

2022
Investigating the Role of Dahuang in Hepatoma Treatment Using Network Pharmacology, Molecular Docking, and Survival Analysis.
    BioMed research international, 2022, Volume: 2022

    Topics: Carcinoma, Hepatocellular; Drugs, Chinese Herbal; Emodin; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Molecular Docking Simulation; Network Pharmacology; Survival Analysis

2022
Combinatorial Effect of Arsenic and Herbal Compounds in Telomerase-Mediated Apoptosis Induction in Liver Cancer.
    Biological trace element research, 2023, Volume: 201, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Arsenic; Arsenic Trioxide; Arsenicals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Emodin; Humans; Liver Neoplasms; Oxides; Quercetin; Telomerase

2023
Effect of emodin combined with cisplatin on the invasion and migration of HepG2 hepatoma cells.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2023, Volume: 74, Issue:4

    Topics: Cadherins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Emodin; Epithelial-Mesenchymal Transition; Hep G2 Cells; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Vimentin

2023
Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway.
    Cancer medicine, 2020, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Drug Synergism; Emodin; Female; Hep G2 Cells; Humans; Liver Neoplasms; Metformin; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2020
Emodin succinyl ester inhibits malignant proliferation and migration of hepatocellular carcinoma by suppressing the interaction of AR and EZH2.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Emodin; Enhancer of Zeste Homolog 2 Protein; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasm Invasiveness; Receptors, Androgen; Signal Transduction; Xenograft Model Antitumor Assays

2020
The effects of fructose and metabolic inhibition on hepatocellular carcinoma.
    Scientific reports, 2020, 10-07, Volume: 10, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Databases, Factual; Emodin; Energy Metabolism; Fructose; Humans; Liver Neoplasms; Mice; Survival Rate

2020
RETRACTED: Physcion 8-O-β-glucopyranoside suppresses tumor growth of Hepatocellular carcinoma by downregulating PIM1.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Emodin; Glucosides; Growth Inhibitors; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Proto-Oncogene Proteins c-pim-1; Xenograft Model Antitumor Assays

2017
Physcion induces apoptosis through triggering endoplasmic reticulum stress in hepatocellular carcinoma.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 99

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Emodin; Endoplasmic Reticulum Stress; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Signal Transduction; Xenograft Model Antitumor Assays

2018
N-acetylaminogalactosyl-decorated biodegradable PLGA-TPGS copolymer nanoparticles containing emodin for the active targeting therapy of liver cancer.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup2

    Topics: Apoptosis; Biological Transport; Drug Carriers; Emodin; Galactose; Hep G2 Cells; Humans; Liver Neoplasms; Molecular Targeted Therapy; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E

2018
Emodin inhibits pancreatic cancer EMT and invasion by up‑regulating microRNA‑1271.
    Molecular medicine reports, 2018, Volume: 18, Issue:3

    Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Emodin; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Immunohistochemistry; Liver Neoplasms; Mice; MicroRNAs; Pancreatic Neoplasms; Protein Kinase Inhibitors

2018
Emodin induces apoptosis in human hepatocellular carcinoma HepaRG cells via the mitochondrial caspase‑dependent pathway.
    Oncology reports, 2018, Volume: 40, Issue:4

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Cycle Checkpoints; Cell Proliferation; Emodin; Gene Expression Regulation, Enzymologic; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Protein Kinase Inhibitors; Reactive Oxygen Species; Tumor Cells, Cultured

2018
Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism.
    International journal of molecular sciences, 2018, Oct-12, Volume: 19, Issue:10

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholesterol; Drug Synergism; Emodin; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Proto-Oncogene Proteins c-akt; Signal Transduction; Sorafenib; Sterol Regulatory Element Binding Protein 2; Xenograft Model Antitumor Assays

2018
RETRACTED: Protective autophagy induced by physcion suppresses hepatocellular carcinoma cell metastasis by inactivating the JAK2/STAT3 Axis.
    Life sciences, 2018, 12-01, Volume: 214

    Topics: Animals; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Emodin; Humans; Janus Kinase 2; Liver Neoplasms; Male; Mice, Inbred BALB C; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2018
Anticancer Effects of Emodin on HepG2 Cell: Evidence from Bioinformatic Analysis.
    BioMed research international, 2019, Volume: 2019

    Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Computational Biology; Emodin; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Protein Interaction Mapping; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Receptors, Purinergic P2; Receptors, Somatostatin; Signal Transduction; Software; Transcriptome

2019
β-Dihydroartemisinin-Emodin Promotes Apoptosis by Activating Extrinsic and Intrinsic Pathways in Human Liver Cancer Cells.
    Annals of clinical and laboratory science, 2019, Volume: 49, Issue:3

    Topics: Apoptosis; Artemisinins; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Shape; Emodin; Hep G2 Cells; Humans; Ki-67 Antigen; Liver Neoplasms; Survivin; Wound Healing

2019
Emodin suppresses migration and invasion through the modulation of CXCR4 expression in an orthotopic model of human hepatocellular carcinoma.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Emodin; Female; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; NF-kappa B; Receptors, CXCR4; RNA, Messenger; Signal Transduction; Wound Healing

2013
Emodin regulating excision repair cross-complementation group 1 through fibroblast growth factor receptor 2 signaling.
    World journal of gastroenterology, 2013, Apr-28, Volume: 19, Issue:16

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Emodin; Endonucleases; Fibroblast Growth Factor 7; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organoplatinum Compounds; Oxaliplatin; Phosphorylation; Receptor, Fibroblast Growth Factor, Type 2; RNA Interference; Signal Transduction; Transfection

2013
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
    Apoptosis : an international journal on programmed cell death, 2013, Volume: 18, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Emodin; Humans; Liver Neoplasms; Reactive Oxygen Species; Receptors, Death Domain; TNF-Related Apoptosis-Inducing Ligand; Transcription Factor CHOP

2013
Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.
    British journal of pharmacology, 2013, Volume: 170, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Drug; Emodin; ErbB Receptors; Female; Hep G2 Cells; Humans; Interleukin-6; Janus Kinase 1; Janus Kinase 2; Liver Neoplasms; Male; Mice; Mice, Nude; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Proto-Oncogene Proteins c-akt; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Time Factors; Transfection; Tumor Burden; Xenograft Model Antitumor Assays

2013
Inhibitory effect of emodin on human hepatoma cell line SMMC-7721 and its mechanism.
    African health sciences, 2015, Volume: 15, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Emodin; Humans; Liver Neoplasms; Microscopy, Electron

2015
A Promising Emodin-Loaded Poly (Lactic-Co-Glycolic Acid)-d-α-Tocopheryl Polyethylene Glycol 1000 Succinate Nanoparticles for Liver Cancer Therapy.
    Pharmaceutical research, 2016, Volume: 33, Issue:1

    Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Delayed-Action Preparations; Drug Delivery Systems; Emodin; Humans; Lactic Acid; Liver Neoplasms; Mice; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley

2016
Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasome.
    Oncotarget, 2016, Jan-26, Volume: 7, Issue:4

    Topics: Animals; Antiviral Agents; Apoptosis; Blotting, Western; Cell Proliferation; Emodin; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Immunoprecipitation; Interferon-alpha; Interferon-beta; Janus Kinases; Liver Neoplasms; Mice; Mice, Nude; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; STAT1 Transcription Factor; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2016
Involvement of PI3K/Akt, ERK and p38 signaling pathways in emodin-mediated extrinsic and intrinsic human hepatoblastoma cell apoptosis.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 92

    Topics: Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Emodin; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Hepatoblastoma; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction

2016
Emodin induces hepatocellular carcinoma cell apoptosis through MAPK and PI3K/AKT signaling pathways in vitro and in vivo.
    Oncology reports, 2016, Volume: 36, Issue:2

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Emodin; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

2016
Physcion 8-O-β-glucopyranoside induces apoptosis, suppresses invasion and inhibits epithelial to mesenchymal transition of hepatocellular carcinoma HepG2 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 83

    Topics: Adenylate Kinase; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Emodin; Epithelial-Mesenchymal Transition; Glucosides; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Invasiveness; Reactive Oxygen Species; Signal Transduction; Sp1 Transcription Factor

2016
Emodin-Loaded PLGA-TPGS Nanoparticles Combined with Heparin Sodium-Loaded PLGA-TPGS Nanoparticles to Enhance Chemotherapeutic Efficacy Against Liver Cancer.
    Pharmaceutical research, 2016, Volume: 33, Issue:11

    Topics: Animals; Antimicrobial Cationic Peptides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Emodin; Fluorescent Dyes; Heparin; Humans; Liver Neoplasms; Male; Mice; Nanoparticles; Particle Size; Surface Properties; Vitamin E

2016
Emodin inhibits the growth of hepatoma cells: finding the common anti-cancer pathway using Huh7, Hep3B, and HepG2 cells.
    Biochemical and biophysical research communications, 2010, Feb-19, Volume: 392, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Emodin; Gene Expression; Gene Expression Profiling; Hep G2 Cells; Humans; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Protein Kinase Inhibitors

2010
Hepatitis C virus and alcohol: same mitotic targets but different signaling pathways.
    Journal of hepatology, 2011, Volume: 54, Issue:5

    Topics: Aurora Kinase A; Aurora Kinases; Biopsy; Carcinoma, Hepatocellular; Central Nervous System Depressants; Cyclin B1; Drug Interactions; Emodin; Ethanol; Hep G2 Cells; Hepatitis C, Chronic; Humans; In Vitro Techniques; Liver Diseases, Alcoholic; Liver Neoplasms; Mitosis; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Signal Transduction; Tubulin

2011
Apoptosis by aloe-emodin is mediated through down-regulation of calpain-2 and ubiquitin-protein ligase E3A in human hepatoma Huh-7 cells.
    Cell biology international, 2012, Volume: 36, Issue:2

    Topics: Aloe; Antineoplastic Agents, Phytogenic; Apoptosis; Calpain; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Damage; Down-Regulation; Emodin; Humans; Liver Neoplasms; Ubiquitin-Protein Ligases

2012
Formulation, antileukemia mechanism, pharmacokinetics, and biodistribution of a novel liposomal emodin.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Emodin; Female; Humans; Leukemia L1210; Liposomes; Liver Neoplasms; Male; Mice; Mice, Inbred ICR; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Random Allocation; Tissue Distribution; Transferrin; Vitamin E

2012
Rubratoxin B induced the secretion of hepatic injury-related colony stimulating factors in human hepatoma cells.
    Toxicology letters, 2003, Nov-30, Volume: 145, Issue:2

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Emodin; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Hepatocytes; Humans; Interleukin-8; Liver Neoplasms; Macrophage Colony-Stimulating Factor; Mycotoxins

2003
[Apoptosis of human hepatoma HepG2 cells induced by emodin in vitro].
    Ai zheng = Aizheng = Chinese journal of cancer, 2003, Volume: 22, Issue:12

    Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Division; Emodin; Enzyme Inhibitors; Flow Cytometry; Humans; Liver Neoplasms; Tumor Cells, Cultured

2003
Emodin-induced apoptosis through p53-dependent pathway in human hepatoma cells.
    Life sciences, 2004, Mar-19, Volume: 74, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Emodin; fas Receptor; Humans; Liver Neoplasms; Signal Transduction; Tumor Suppressor Protein p53

2004
Aloe vera (Aloe barbadensis, Aloe capensis).
    Journal of the Society for Integrative Oncology, 2007,Spring, Volume: 5, Issue:2

    Topics: Aloe; Apoptosis; Emodin; Humans; Liver Neoplasms

2007
Apoptosis-inducing activity of new pyrazole emodin derivatives in human hepatocellular carcinoma HepG2 cells.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:6

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; DNA Fragmentation; Dose-Response Relationship, Drug; Emodin; Enzyme Activation; Formazans; Humans; Liver Neoplasms; Molecular Structure; Poly(ADP-ribose) Polymerases; Tetrazolium Salts; Time Factors

2007
Critical role of oxidative stress and sustained JNK activation in aloe-emodin-mediated apoptotic cell death in human hepatoma cells.
    Carcinogenesis, 2007, Volume: 28, Issue:9

    Topics: Aloe; Apoptosis; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Emodin; Glutathione; Glutathione Disulfide; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase Kinases; Oxidative Stress; Plant Extracts

2007
Inhibition of casein kinase 2 enhances the death ligand- and natural kiler cell-induced hepatocellular carcinoma cell death.
    Clinical and experimental immunology, 2008, Volume: 152, Issue:2

    Topics: Apoptosis; Carcinoma, Hepatocellular; Casein Kinase II; Cytoplasmic Granules; Cytotoxicity, Immunologic; Emodin; Fas Ligand Protein; Humans; Killer Cells, Natural; Liver Neoplasms; Protein Kinase Inhibitors; Recombinant Proteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured

2008