emodin has been researched along with Breast Neoplasms in 41 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 6 (14.63) | 29.6817 |
| 2010's | 19 (46.34) | 24.3611 |
| 2020's | 14 (34.15) | 2.80 |
| Authors | Studies |
|---|---|
| Jabor Gozzi, G | 1 |
| Bouaziz, Z | 1 |
| Winter, E | 1 |
| Daflon-Yunes, N | 1 |
| Aichele, D | 1 |
| Nacereddine, A | 1 |
| Marminon, C | 1 |
| Valdameri, G | 1 |
| Zeinyeh, W | 1 |
| Bollacke, A | 1 |
| Guillon, J | 1 |
| Lacoudre, A | 1 |
| Pinaud, N | 1 |
| Cadena, SM | 1 |
| Jose, J | 1 |
| Le Borgne, M | 1 |
| Di Pietro, A | 1 |
| Cheng, K | 1 |
| Zhou, J | 3 |
| Zhao, Y | 3 |
| Chen, Y | 5 |
| Ming, L | 1 |
| Huang, D | 2 |
| Yang, R | 1 |
| Lin, Z | 1 |
| Chen, D | 1 |
| Stringaro, A | 1 |
| Serra, S | 1 |
| Gori, A | 1 |
| Calcabrini, A | 1 |
| Colone, M | 1 |
| Dupuis, ML | 1 |
| Spadaro, F | 1 |
| Cecchetti, S | 1 |
| Vitali, A | 1 |
| Sakalli-Tecim, E | 2 |
| Gur-Dedeoglu, B | 1 |
| Guray, NT | 2 |
| Okon, E | 1 |
| Gaweł-Bęben, K | 1 |
| Jarzab, A | 1 |
| Koch, W | 1 |
| Kukula-Koch, W | 1 |
| Wawruszak, A | 1 |
| Fu, M | 1 |
| Tang, W | 1 |
| Liu, JJ | 1 |
| Gong, XQ | 1 |
| Kong, L | 2 |
| Yao, XM | 1 |
| Jing, M | 1 |
| Cai, FY | 1 |
| Li, XT | 1 |
| Ju, RJ | 1 |
| Zou, G | 1 |
| Zhang, X | 2 |
| Wang, L | 6 |
| Li, X | 5 |
| Xie, T | 1 |
| Zhao, J | 1 |
| Yan, J | 1 |
| Ye, H | 1 |
| Jiao, S | 1 |
| Xiang, R | 1 |
| Shi, Y | 1 |
| Ponnusamy, L | 1 |
| Kothandan, G | 1 |
| Manoharan, R | 1 |
| Bhattacharjee, M | 1 |
| Upadhyay, P | 1 |
| Sarker, S | 1 |
| Basu, A | 1 |
| Das, S | 1 |
| Ghosh, A | 1 |
| Ghosh, S | 1 |
| Adhikary, A | 1 |
| Nese, M | 1 |
| Riboli, G | 1 |
| Brighetti, G | 1 |
| Sassi, V | 1 |
| Camela, E | 1 |
| Caselli, G | 1 |
| Sassaroli, S | 1 |
| Borlimi, R | 1 |
| Aucoin, M | 1 |
| Cooley, K | 1 |
| Saunders, PR | 1 |
| Carè, J | 1 |
| Anheyer, D | 1 |
| Medina, DN | 1 |
| Cardozo, V | 1 |
| Remy, D | 1 |
| Hannan, N | 1 |
| Garber, A | 1 |
| Velayos, M | 1 |
| Muñoz-Serrano, AJ | 1 |
| Estefanía-Fernández, K | 1 |
| Sarmiento Caldas, MC | 1 |
| Moratilla Lapeña, L | 1 |
| López-Santamaría, M | 1 |
| López-Gutiérrez, JC | 1 |
| Li, J | 2 |
| Zhang, J | 1 |
| Shen, S | 1 |
| Zhang, B | 2 |
| Yu, WW | 1 |
| Toyoda, H | 1 |
| Huang, DQ | 1 |
| Le, MH | 1 |
| Nguyen, MH | 1 |
| Huang, R | 1 |
| Zhu, L | 1 |
| Wang, J | 9 |
| Xue, L | 1 |
| Liu, L | 2 |
| Yan, X | 2 |
| Huang, S | 1 |
| Li, Y | 6 |
| Xu, T | 1 |
| Li, C | 2 |
| Ji, F | 1 |
| Ming, F | 1 |
| Cheng, J | 1 |
| Wang, Y | 7 |
| Zhao, H | 1 |
| Hong, S | 1 |
| Chen, K | 2 |
| Zhao, XA | 1 |
| Zou, L | 1 |
| Sang, D | 1 |
| Shao, H | 1 |
| Guan, X | 1 |
| Chen, X | 3 |
| Wei, J | 1 |
| Zhu, C | 1 |
| Wu, C | 1 |
| Moore, HB | 1 |
| Barrett, CD | 1 |
| Moore, EE | 1 |
| Jhunjhunwala, R | 1 |
| McIntyre, RC | 1 |
| Moore, PK | 1 |
| Hajizadeh, N | 1 |
| Talmor, DS | 1 |
| Sauaia, A | 1 |
| Yaffe, MB | 1 |
| Liu, C | 3 |
| Lin, Y | 1 |
| Dong, Y | 1 |
| Wu, Y | 1 |
| Bao, Y | 1 |
| Yan, H | 2 |
| Ma, J | 2 |
| Fernández-Cuadros, ME | 1 |
| Albaladejo-Florín, MJ | 1 |
| Álava-Rabasa, S | 1 |
| Usandizaga-Elio, I | 1 |
| Martinez-Quintanilla Jimenez, D | 1 |
| Peña-Lora, D | 1 |
| Neira-Borrajo, I | 1 |
| López-Muñoz, MJ | 1 |
| Rodríguez-de-Cía, J | 1 |
| Pérez-Moro, OS | 1 |
| Abdallah, M | 1 |
| Alsaleh, H | 1 |
| Baradwan, A | 1 |
| Alfawares, R | 1 |
| Alobaid, A | 1 |
| Rasheed, A | 1 |
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| Wendel Garcia, PD | 1 |
| Fumeaux, T | 1 |
| Guerci, P | 1 |
| Heuberger, DM | 1 |
| Montomoli, J | 2 |
| Roche-Campo, F | 1 |
| Schuepbach, RA | 1 |
| Hilty, MP | 1 |
| Poloni, TE | 1 |
| Carlos, AF | 1 |
| Cairati, M | 1 |
| Cutaia, C | 1 |
| Medici, V | 1 |
| Marelli, E | 1 |
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| Davin, A | 1 |
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| McPhail, MJW | 1 |
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| Edwards, LA | 1 |
| Alqarawi, W | 1 |
| Birnie, DH | 1 |
| Golian, M | 1 |
| Nair, GM | 1 |
| Nery, PB | 1 |
| Klein, A | 1 |
| Davis, DR | 1 |
| Sadek, MM | 1 |
| Neilipovitz, D | 1 |
| Johnson, CB | 1 |
| Green, MS | 1 |
| Redpath, C | 1 |
| Miller, DC | 1 |
| Beamer, P | 1 |
| Billheimer, D | 1 |
| Subbian, V | 1 |
| Sorooshian, A | 1 |
| Campbell, BS | 1 |
| Mosier, JM | 1 |
| Novaretti, JV | 1 |
| Astur, DC | 1 |
| Cavalcante, ELB | 1 |
| Kaleka, CC | 1 |
| Amaro, JT | 1 |
| Cohen, M | 1 |
| Huang, W | 1 |
| Li, T | 1 |
| Ling, Y | 1 |
| Qian, ZP | 1 |
| Zhang, YY | 1 |
| Xu, SB | 1 |
| Liu, XH | 1 |
| Xia, L | 1 |
| Yang, Y | 4 |
| Lu, SH | 1 |
| Lu, HZ | 1 |
| Zhang, R | 2 |
| Ma, JX | 1 |
| Tang, S | 1 |
| Li, CM | 1 |
| Wan, J | 1 |
| Wang, JF | 1 |
| Ma, JQ | 1 |
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| Chen, HY | 2 |
| Mi, SL | 1 |
| Chen, SY | 1 |
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| Nogueira, F | 1 |
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| M Piedade, MF | 1 |
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| Florindo, PR | 1 |
| Moreira, R | 1 |
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| Delley, MF | 1 |
| Laga, SM | 1 |
| Mayer, JM | 1 |
| Sutjarit, N | 1 |
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| Weerachayaphorn, J | 1 |
| Piyachaturawat, P | 1 |
| Suksamrarn, A | 1 |
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| Papachristou, DJ | 1 |
| Blair, HC | 1 |
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| Shen, P | 1 |
| Zeng, N | 1 |
| Yan, D | 1 |
| Cui, L | 1 |
| Yang, K | 2 |
| Zhai, C | 1 |
| Yang, M | 1 |
| Lao, X | 1 |
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| Wang, S | 3 |
| Ye, W | 1 |
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| Chen, R | 2 |
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| Shaheen, MY | 1 |
| Basudan, AM | 1 |
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| van den Beucken, JJJP | 1 |
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| Gao, Q | 2 |
| Guo, X | 1 |
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| Jia, X | 2 |
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| Lu, C | 2 |
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| Melku, M | 1 |
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4 reviews available for emodin and Breast Neoplasms
| Article | Year |
|---|---|
Therapeutic Potential of 1,8-Dihydroanthraquinone Derivatives for Breast Cancer.
Topics: Anthraquinones; Breast Neoplasms; Emodin; Female; Humans; Plant Extracts; Polygonaceae; Rheum | 2023 |
Combination of targeted daunorubicin liposomes and targeted emodin liposomes for treatment of invasive breast cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Drug Delive | 2020 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; | 2022 |
P2X7 receptor: a critical regulator and potential target for breast cancer.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Breast Neoplasms; Cat's Claw; Cations; Disease Progre | 2021 |
1 trial available for emodin and Breast Neoplasms
37 other studies available for emodin and Breast Neoplasms
| Article | Year |
|---|---|
Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biologic | 2015 |
pH-responsive and CD44-targeting polymer micelles based on CD44p-conjugated amphiphilic block copolymer PEG-
Topics: Breast Neoplasms; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Emodin; Female; Humans; Hy | 2022 |
Peptide-Mediated Targeted Delivery of Aloe-Emodin as Anticancer Drug.
Topics: Aloe; Anthraquinones; Antineoplastic Agents; Apoptosis; Biological Products; Breast Neoplasms; Emodi | 2022 |
Systems biology based miRNA-mRNA expression pattern analysis of Emodin in breast cancer cell lines.
Topics: Breast Neoplasms; Emodin; Female; Humans; MCF-7 Cells; MicroRNAs; RNA, Messenger; Systems Biology | 2023 |
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, | 2020 |
Berberine and Emodin abrogates breast cancer growth and facilitates apoptosis through inactivation of SIK3-induced mTOR and Akt signaling pathway.
Topics: Apoptosis; Berberine; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Surviv | 2020 |
Combinatorial therapy of Thymoquinone and Emodin synergistically enhances apoptosis, attenuates cell migration and reduces stemness efficiently in breast cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Bre | 2020 |
Identification of Potential Therapeutic Genes and Pathways in Phytoestrogen Emodin Treated Breast Cancer Cell Lines via Network Biology Approaches.
Topics: Biology; Breast Neoplasms; Cell Line, Tumor; Emodin; Female; Gene Expression Regulation, Neoplastic; | 2022 |
The anti-breast cancer property of physcion via oxidative stress-mediated mitochondrial apoptosis and immune response.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Survival; Dose-Response Relationsh | 2021 |
The effects and mechanisms of aloe-emodin on reversing adriamycin-induced resistance of MCF-7/ADR cells.
Topics: Aloe; Breast Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Emodin; Female; Humans; MCF-7 Cells | 2021 |
Inhibition of cell-intrinsic NF-κB activity and metastatic abilities of breast cancer by aloe-emodin and emodic-acid isolated from Asphodelus microcarpus.
Topics: Aloe; Anthraquinones; Breast Neoplasms; Emodin; Female; Humans; NF-kappa B | 2021 |
In Vitro Estrogenic and Breast Cancer Inhibitory Activities of Chemical Constituents Isolated from Rheum undulatum L.
Topics: Anthraquinones; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dr | 2018 |
Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Cel | 2018 |
Magnetic liposomal emodin composite with enhanced killing efficiency against breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Emodin; Female; Ferric Compounds; Hemoly | 2019 |
Anthraquinone emodin inhibits human cancer cell invasiveness by antagonizing P2X7 receptors.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cal | 2013 |
Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Carci | 2013 |
Synergistic effects of curcumin with emodin against the proliferation and invasion of breast cancer cells through upregulation of miR-34a.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Synergism; Emodin; | 2013 |
Emodin inhibits breast cancer cell proliferation through the ERα-MAPK/Akt-cyclin D1/Bcl-2 signaling pathway.
Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cyclin D1; Emodin; E | 2014 |
Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs.
Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Adhesion; Cell Movement; Cell Prolifer | 2014 |
Inhibitory effect of emodin on migration, invasion and metastasis of human breast cancer MDA-MB-231 cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Body Weight; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Dose | 2015 |
The anthraquinone derivative Emodin inhibits angiogenesis and metastasis through downregulating Runx2 activity in breast cancer.
Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Proliferation; Core Binding Factor Alpha 1 | 2015 |
Antiproliferative, antibacterial and antifungal activity of the lichen Xanthoria parietina and its secondary metabolite parietin.
Topics: Anti-Bacterial Agents; Antifungal Agents; Apoptosis; Breast Neoplasms; Cell Cycle Proteins; Cell Lin | 2015 |
Exploring a Novel Target Treatment on Breast Cancer: Aloe-emodin Mediated Photodynamic Therapy Induced Cell Apoptosis and Inhibited Cell Metastasis.
Topics: Aloe; Apoptosis; Breast Neoplasms; Emodin; Female; Humans; Neoplasm Metastasis; Photochemotherapy | 2016 |
Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages.
Topics: Animals; Biomarkers; Breast Neoplasms; Cell Communication; Cell Line, Tumor; Cell Survival; Disease | 2016 |
Aloe-emodin inhibits HER-2 expression through the downregulation of Y-box binding protein-1 in HER-2-overexpressing human breast cancer cells.
Topics: Anthraquinones; Breast Neoplasms; Carcinogenesis; Cell Movement; Down-Regulation; Emodin; Female; Gl | 2016 |
Physcion 8-O-β-glucopyranoside suppresses the metastasis of breast cancer in vitro and in vivo by modulating DNMT1.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; DNA (Cytosine-5-)-Methyltransferase 1; D | 2017 |
Emodin-induced apoptosis in human breast cancer BCap-37 cells through the mitochondrial signaling pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Lin | 2008 |
Effects of emodin on the gene expression profiling of human breast carcinoma cells.
Topics: Apoptosis; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Survival; Cells, Cultured; Emodin; Ge | 2009 |
Repair and reconstruction of a resected tumor defect using a composite of tissue flap-nanotherapeutic-silk fibroin and chitosan scaffold.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chitosan; Emodin; Female; Humans | 2011 |
Emodin loaded solid lipid nanoparticles: preparation, characterization and antitumor activity studies.
Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Ce | 2012 |
Emodin affects ERCC1 expression in breast cancer cells.
Topics: Blotting, Western; Breast Neoplasms; Cell Survival; Cisplatin; DNA-Binding Proteins; Doxorubicin; Em | 2012 |
DNA ploidy and S phase fraction of breast and ovarian tumor cells treated with a natural anthracycline analog (aloin).
Topics: Aloe; Breast Neoplasms; DNA; Emodin; Female; Humans; Ovarian Neoplasms; Ploidies; S Phase; Tumor Cel | 2005 |
Cytotoxicity of a natural anthraquinone (Aloin) against human breast cancer cell lines with and without ErbB-2: topoisomerase IIalpha coamplification.
Topics: Antigens, Neoplasm; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cyclin B; DNA Topoisomerases, Typ | 2006 |
Role of exon-16-deleted HER2 in breast carcinomas.
Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents | 2006 |
Silk fibroin mediated delivery of liposomal emodin to breast cancer cells.
Topics: Animals; Antineoplastic Agents; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proli | 2007 |
Suppressed transformation and induced differentiation of HER-2/neu-overexpressing breast cancer cells by emodin.
Topics: Breast Neoplasms; Cell Differentiation; Cell Division; Cell Line, Transformed; Cell Transformation, | 1995 |
Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties.
Topics: 3T3 Cells; Animals; Breast Neoplasms; Cell Division; Cell Transformation, Neoplastic; Emodin; Enzyme | 1998 |