emodin has been researched along with Bladder Cancer in 4 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emodin increased the cellular ROS level and effectively enhanced the cisplatin-induced cytotoxicity of T24 and J82 human bladder cancer cells through decreasing glutathione-cisplatin (GSH-cisplatin) conjugates." | 7.83 | Emodin enhances cisplatin-induced cytotoxicity in human bladder cancer cells through ROS elevation and MRP1 downregulation. ( Chen, Y; Hu, Z; Li, H; Li, X; Liang, X; Shi, G; Wang, H; Wang, J; Yin, X, 2016) |
| "Emodin increased the cellular ROS level and effectively enhanced the cisplatin-induced cytotoxicity of T24 and J82 human bladder cancer cells through decreasing glutathione-cisplatin (GSH-cisplatin) conjugates." | 3.83 | Emodin enhances cisplatin-induced cytotoxicity in human bladder cancer cells through ROS elevation and MRP1 downregulation. ( Chen, Y; Hu, Z; Li, H; Li, X; Liang, X; Shi, G; Wang, H; Wang, J; Yin, X, 2016) |
| "Emodin treatment did not induce specific cell cycle arrest, but it altered epigenetic modifications." | 1.42 | Emodin modulates epigenetic modifications and suppresses bladder carcinoma cell growth. ( Cha, TL; Chang, SY; Chen, TT; Chuang, MJ; Ho, JY; Huang, SM; Liu, SY; Sun, GH; Sun, KH; Tang, SH; Wu, ST; Yu, CP; Yu, DS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, TL | 2 |
| Chuang, MJ | 2 |
| Tang, SH | 2 |
| Wu, ST | 1 |
| Sun, KH | 1 |
| Chen, TT | 1 |
| Sun, GH | 2 |
| Chang, SY | 2 |
| Yu, CP | 2 |
| Ho, JY | 1 |
| Liu, SY | 1 |
| Huang, SM | 2 |
| Yu, DS | 2 |
| Huang, HS | 1 |
| Wu, HU | 1 |
| Tsai, YT | 1 |
| Hsiao, PW | 1 |
| Li, X | 1 |
| Wang, H | 1 |
| Wang, J | 1 |
| Chen, Y | 1 |
| Yin, X | 1 |
| Shi, G | 1 |
| Li, H | 1 |
| Hu, Z | 1 |
| Liang, X | 1 |
| Lin, JG | 1 |
| Chen, GW | 1 |
| Li, TM | 1 |
| Chouh, ST | 1 |
| Tan, TW | 1 |
| Chung, JG | 1 |
4 other studies available for emodin and Bladder Cancer
| Article | Year |
|---|---|
Emodin modulates epigenetic modifications and suppresses bladder carcinoma cell growth.
Topics: Cell Cycle Checkpoints; Cell Proliferation; Chromatin Immunoprecipitation; DNA Methylation; Emodin; | 2015 |
Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Growth Processes; Cell Line, Tumor; Down- | 2014 |
Emodin enhances cisplatin-induced cytotoxicity in human bladder cancer cells through ROS elevation and MRP1 downregulation.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Down-Regulation; Drug Syner | 2016 |
Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway.
Topics: Anthraquinones; Apoptosis; Emodin; Enzyme Inhibitors; Humans; Tumor Cells, Cultured; Tumor Suppresso | 2006 |