emodin has been researched along with Atherosclerosis in 9 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Atherosclerosis is an inflammatory disease of high lethality associated with endothelial dysfunction." | 5.72 | Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy. ( Chen, H; Chen, Y; Cui, H; Li, X; Lin, Y; Liu, X; Meng, Z; Shi, Y; Tang, X; Wang, Z; Xu, H; Yang, B; Zhang, Y; Zhao, H; Zhao, L; Zhu, M, 2022) |
| "Emodin was administered at 10, 30, or 100 mg/kg, while simvastatin was administered at 10 mg/kg." | 5.62 | Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol. ( Guo, XJ; Liu, SY; Lv, CF; Wang, J; Wu, JH; Xu, Y; Zhang, H; Zhang, J, 2021) |
| "Emodin has been used as an anti-inflammatory agent and inflammation is a crucial feature of atherosclerosis." | 3.77 | Sonodynamic effect of an anti-inflammatory agent--emodin on macrophages. ( Cao, W; Cheng, J; Gao, Q; Guo, S; Jin, Y; Li, B; Li, J; Shi, S; Tian, Y; Wang, F; Wang, H; Zhang, Z; Zhu, B, 2011) |
| "Atherosclerosis is an inflammatory disease of high lethality associated with endothelial dysfunction." | 1.72 | Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy. ( Chen, H; Chen, Y; Cui, H; Li, X; Lin, Y; Liu, X; Meng, Z; Shi, Y; Tang, X; Wang, Z; Xu, H; Yang, B; Zhang, Y; Zhao, H; Zhao, L; Zhu, M, 2022) |
| "Emodin was administered at 10, 30, or 100 mg/kg, while simvastatin was administered at 10 mg/kg." | 1.62 | Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol. ( Guo, XJ; Liu, SY; Lv, CF; Wang, J; Wu, JH; Xu, Y; Zhang, H; Zhang, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 4 (44.44) | 2.80 |
| Authors | Studies |
|---|---|
| Tang, X | 1 |
| Zhang, Y | 3 |
| Liu, X | 1 |
| Li, X | 1 |
| Zhao, H | 1 |
| Cui, H | 1 |
| Shi, Y | 1 |
| Chen, Y | 1 |
| Xu, H | 2 |
| Meng, Z | 1 |
| Zhao, L | 1 |
| Chen, H | 1 |
| Wang, Z | 1 |
| Zhu, M | 1 |
| Lin, Y | 1 |
| Yang, B | 1 |
| Wang, X | 1 |
| Yang, S | 1 |
| Li, Y | 1 |
| Jin, X | 1 |
| Lu, J | 1 |
| Wu, M | 1 |
| Luo, N | 1 |
| Fang, J | 1 |
| Wei, L | 1 |
| Sahebkar, A | 1 |
| Little, PJ | 1 |
| Xu, S | 1 |
| Luo, C | 1 |
| Li, G | 1 |
| Wu, JH | 1 |
| Lv, CF | 1 |
| Guo, XJ | 1 |
| Zhang, H | 1 |
| Zhang, J | 1 |
| Xu, Y | 1 |
| Wang, J | 1 |
| Liu, SY | 1 |
| Geng, C | 1 |
| Hidru, TH | 1 |
| Zhi, L | 1 |
| Tao, M | 1 |
| Zou, L | 1 |
| Chen, C | 1 |
| Li, H | 1 |
| Liu, Y | 2 |
| Zhou, M | 1 |
| Pan, L | 1 |
| Wen, J | 1 |
| Guo, Y | 1 |
| Chen, K | 1 |
| Meng, G | 1 |
| Lou, C | 1 |
| Yang, H | 1 |
| Gao, Q | 2 |
| Wang, F | 1 |
| Guo, S | 1 |
| Li, J | 1 |
| Zhu, B | 1 |
| Cheng, J | 1 |
| Jin, Y | 1 |
| Li, B | 1 |
| Wang, H | 1 |
| Shi, S | 1 |
| Zhang, Z | 1 |
| Cao, W | 1 |
| Tian, Y | 1 |
| Hei, ZQ | 1 |
| Huang, HQ | 1 |
| Tan, HM | 1 |
| Liu, PQ | 1 |
| Zhao, LZ | 1 |
| Chen, SR | 1 |
| Huang, WG | 1 |
| Chen, FY | 1 |
| Guo, FF | 1 |
3 reviews available for emodin and Atherosclerosis
| Article | Year |
|---|---|
Role of emodin in atherosclerosis and other cardiovascular diseases: Pharmacological effects, mechanisms, and potential therapeutic target as a phytochemical.
Topics: Aged; Atherosclerosis; Cardiovascular Diseases; Drugs, Chinese Herbal; Emodin; Humans; Phytochemical | 2023 |
Emodin in atherosclerosis prevention: Pharmacological actions and therapeutic potential.
Topics: Animals; Atherosclerosis; Blood Platelets; Drugs, Chinese Herbal; Emodin; Endothelium; Humans; Infla | 2021 |
Sonodynamic therapy: A potential treatment for atherosclerosis.
Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chal | 2018 |
6 other studies available for emodin and Atherosclerosis
| Article | Year |
|---|---|
Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy.
Topics: Adaptor Proteins, Signal Transducing; Aloe; Animals; Aorta; Atherosclerosis; Autophagy; Collagen; Di | 2022 |
Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol.
Topics: Animals; Antioxidants; Aorta; Atherosclerosis; Cholesterol, HDL; Cholesterol, LDL; Disease Models, A | 2021 |
Emodin promotes atherosclerotic plaque stability in fat-fed apolipoprotein E-deficient mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Dietary Fats; Emodin; Growth Inhibitors; Hydroxymethylg | 2008 |
Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells.
Topics: Atherosclerosis; beta-Cyclodextrins; Cell Survival; Cells, Cultured; Cholesterol; Cytokines; Emodin; | 2010 |
Sonodynamic effect of an anti-inflammatory agent--emodin on macrophages.
Topics: Anti-Inflammatory Agents; Apoptosis; Atherosclerosis; Cell Culture Techniques; Emodin; Fluorescent A | 2011 |
Emodin inhibits dietary induced atherosclerosis by antioxidation and regulation of the sphingomyelin pathway in rabbits.
Topics: Animals; Antioxidants; Apoptosis; Atherosclerosis; Ceramides; Dietary Fats; Emodin; Lipids; Male; Ra | 2006 |