Page last updated: 2024-10-26

emodin and Atherosclerosis

emodin has been researched along with Atherosclerosis in 9 studies

Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.

Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.

Research Excerpts

ExcerptRelevanceReference
"Atherosclerosis is an inflammatory disease of high lethality associated with endothelial dysfunction."5.72Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy. ( Chen, H; Chen, Y; Cui, H; Li, X; Lin, Y; Liu, X; Meng, Z; Shi, Y; Tang, X; Wang, Z; Xu, H; Yang, B; Zhang, Y; Zhao, H; Zhao, L; Zhu, M, 2022)
"Emodin was administered at 10, 30, or 100 mg/kg, while simvastatin was administered at 10 mg/kg."5.62Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol. ( Guo, XJ; Liu, SY; Lv, CF; Wang, J; Wu, JH; Xu, Y; Zhang, H; Zhang, J, 2021)
"Emodin has been used as an anti-inflammatory agent and inflammation is a crucial feature of atherosclerosis."3.77Sonodynamic effect of an anti-inflammatory agent--emodin on macrophages. ( Cao, W; Cheng, J; Gao, Q; Guo, S; Jin, Y; Li, B; Li, J; Shi, S; Tian, Y; Wang, F; Wang, H; Zhang, Z; Zhu, B, 2011)
"Atherosclerosis is an inflammatory disease of high lethality associated with endothelial dysfunction."1.72Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy. ( Chen, H; Chen, Y; Cui, H; Li, X; Lin, Y; Liu, X; Meng, Z; Shi, Y; Tang, X; Wang, Z; Xu, H; Yang, B; Zhang, Y; Zhao, H; Zhao, L; Zhu, M, 2022)
"Emodin was administered at 10, 30, or 100 mg/kg, while simvastatin was administered at 10 mg/kg."1.62Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol. ( Guo, XJ; Liu, SY; Lv, CF; Wang, J; Wu, JH; Xu, Y; Zhang, H; Zhang, J, 2021)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's4 (44.44)2.80

Authors

AuthorsStudies
Tang, X1
Zhang, Y3
Liu, X1
Li, X1
Zhao, H1
Cui, H1
Shi, Y1
Chen, Y1
Xu, H2
Meng, Z1
Zhao, L1
Chen, H1
Wang, Z1
Zhu, M1
Lin, Y1
Yang, B1
Wang, X1
Yang, S1
Li, Y1
Jin, X1
Lu, J1
Wu, M1
Luo, N1
Fang, J1
Wei, L1
Sahebkar, A1
Little, PJ1
Xu, S1
Luo, C1
Li, G1
Wu, JH1
Lv, CF1
Guo, XJ1
Zhang, H1
Zhang, J1
Xu, Y1
Wang, J1
Liu, SY1
Geng, C1
Hidru, TH1
Zhi, L1
Tao, M1
Zou, L1
Chen, C1
Li, H1
Liu, Y2
Zhou, M1
Pan, L1
Wen, J1
Guo, Y1
Chen, K1
Meng, G1
Lou, C1
Yang, H1
Gao, Q2
Wang, F1
Guo, S1
Li, J1
Zhu, B1
Cheng, J1
Jin, Y1
Li, B1
Wang, H1
Shi, S1
Zhang, Z1
Cao, W1
Tian, Y1
Hei, ZQ1
Huang, HQ1
Tan, HM1
Liu, PQ1
Zhao, LZ1
Chen, SR1
Huang, WG1
Chen, FY1
Guo, FF1

Reviews

3 reviews available for emodin and Atherosclerosis

ArticleYear
Role of emodin in atherosclerosis and other cardiovascular diseases: Pharmacological effects, mechanisms, and potential therapeutic target as a phytochemical.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 161

    Topics: Aged; Atherosclerosis; Cardiovascular Diseases; Drugs, Chinese Herbal; Emodin; Humans; Phytochemical

2023
Emodin in atherosclerosis prevention: Pharmacological actions and therapeutic potential.
    European journal of pharmacology, 2021, Jan-05, Volume: 890

    Topics: Animals; Atherosclerosis; Blood Platelets; Drugs, Chinese Herbal; Emodin; Endothelium; Humans; Infla

2021
Sonodynamic therapy: A potential treatment for atherosclerosis.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Atherosclerosis; Berberine; Cell Death; Chal

2018

Other Studies

6 other studies available for emodin and Atherosclerosis

ArticleYear
Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy.
    European journal of pharmacology, 2022, Feb-05, Volume: 916

    Topics: Adaptor Proteins, Signal Transducing; Aloe; Animals; Aorta; Atherosclerosis; Autophagy; Collagen; Di

2022
Low Dose of Emodin Inhibits Hypercholesterolemia in a Rat Model of High Cholesterol.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Jul-14, Volume: 27

    Topics: Animals; Antioxidants; Aorta; Atherosclerosis; Cholesterol, HDL; Cholesterol, LDL; Disease Models, A

2021
Emodin promotes atherosclerotic plaque stability in fat-fed apolipoprotein E-deficient mice.
    The Tohoku journal of experimental medicine, 2008, Volume: 215, Issue:1

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Dietary Fats; Emodin; Growth Inhibitors; Hydroxymethylg

2008
Emodin suppresses lipopolysaccharide-induced pro-inflammatory responses and NF-κB activation by disrupting lipid rafts in CD14-negative endothelial cells.
    British journal of pharmacology, 2010, Volume: 161, Issue:7

    Topics: Atherosclerosis; beta-Cyclodextrins; Cell Survival; Cells, Cultured; Cholesterol; Cytokines; Emodin;

2010
Sonodynamic effect of an anti-inflammatory agent--emodin on macrophages.
    Ultrasound in medicine & biology, 2011, Volume: 37, Issue:9

    Topics: Anti-Inflammatory Agents; Apoptosis; Atherosclerosis; Cell Culture Techniques; Emodin; Fluorescent A

2011
Emodin inhibits dietary induced atherosclerosis by antioxidation and regulation of the sphingomyelin pathway in rabbits.
    Chinese medical journal, 2006, May-20, Volume: 119, Issue:10

    Topics: Animals; Antioxidants; Apoptosis; Atherosclerosis; Ceramides; Dietary Fats; Emodin; Lipids; Male; Ra

2006