emodin has been researched along with Angiogenesis, Pathologic in 9 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we tested the ability of emodin, a Chinese herb-derived compound, to inhibit breast cancer growth in mice and examined the underlying mechanisms." | 7.83 | Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages. ( Fan, D; Hodge, J; Iwanowycz, S; Wang, J; Wang, Y; Yu, F, 2016) |
| " In this study, we tested the ability of emodin, a Chinese herb-derived compound, to inhibit breast cancer growth in mice and examined the underlying mechanisms." | 3.83 | Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages. ( Fan, D; Hodge, J; Iwanowycz, S; Wang, J; Wang, Y; Yu, F, 2016) |
| "Emodin was used to incubate ATC cells or to treat animals orally." | 1.48 | Emodin suppresses angiogenesis and metastasis in anaplastic thyroid cancer by affecting TRAF6‑mediated pathways in vivo and in vitro. ( Shi, GH; Zhou, L, 2018) |
| "Emodin is a traditional Chinese medicine, which has been demonstrated to inhibit the growth of pancreatic cancer cells." | 1.42 | Emodin inhibits angiogenesis in pancreatic cancer by regulating the transforming growth factor-β/drosophila mothers against decapentaplegic pathway and angiogenesis-associated microRNAs. ( Chen, H; Chen, L; Chen, MY; Guo, JQ; Hu, P; Ji, X; Lin, SZ; Lu, D; Tong, HF; Wang, ZH; Xu, HT; Xu, JB, 2015) |
| "Emodin has been showed to induce apoptosis of pancreatic cancer cells and inhibit tumor growth in our previous studies." | 1.38 | Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis. ( Chen, H; Chen, KJ; Guo, HC; Lin, SZ; Liu, DL; Liu, HB; Ni, ZL; Tong, HF; Wang, ZH; Wei, WT, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Zou, G | 1 |
| Zhang, X | 1 |
| Wang, L | 2 |
| Li, X | 1 |
| Xie, T | 1 |
| Zhao, J | 1 |
| Yan, J | 1 |
| Ye, H | 1 |
| Jiao, S | 1 |
| Xiang, R | 1 |
| Shi, Y | 1 |
| Shi, GH | 1 |
| Zhou, L | 1 |
| Chen, R | 1 |
| Zhang, J | 1 |
| Hu, Y | 1 |
| Wang, S | 1 |
| Chen, M | 1 |
| Wang, Y | 2 |
| Lin, SZ | 2 |
| Xu, JB | 1 |
| Ji, X | 1 |
| Chen, H | 2 |
| Xu, HT | 1 |
| Hu, P | 1 |
| Chen, L | 1 |
| Guo, JQ | 1 |
| Chen, MY | 1 |
| Lu, D | 1 |
| Wang, ZH | 2 |
| Tong, HF | 2 |
| Iwanowycz, S | 1 |
| Wang, J | 1 |
| Hodge, J | 1 |
| Yu, F | 1 |
| Fan, D | 1 |
| Wei, WT | 1 |
| Chen, KJ | 1 |
| Ni, ZL | 1 |
| Liu, HB | 1 |
| Guo, HC | 1 |
| Liu, DL | 1 |
| Kwak, HJ | 1 |
| Park, MJ | 1 |
| Park, CM | 1 |
| Moon, SI | 1 |
| Yoo, DH | 1 |
| Lee, HC | 1 |
| Lee, SH | 1 |
| Kim, MS | 1 |
| Lee, HW | 1 |
| Shin, WS | 1 |
| Park, IC | 1 |
| Rhee, CH | 1 |
| Hong, SI | 1 |
| Kaneshiro, T | 1 |
| Morioka, T | 1 |
| Inamine, M | 1 |
| Kinjo, T | 1 |
| Arakaki, J | 1 |
| Chiba, I | 1 |
| Sunagawa, N | 1 |
| Suzui, M | 1 |
| Yoshimi, N | 1 |
| Cárdenas, C | 1 |
| Quesada, AR | 1 |
| Medina, MA | 1 |
1 review available for emodin and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Potential antineoplastic effects of Aloe-emodin: a comprehensive review.
Topics: Aloe; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Transformation, | 2014 |
8 other studies available for emodin and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, | 2020 |
Emodin suppresses angiogenesis and metastasis in anaplastic thyroid cancer by affecting TRAF6‑mediated pathways in vivo and in vitro.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Prolifer | 2018 |
Emodin inhibits angiogenesis in pancreatic cancer by regulating the transforming growth factor-β/drosophila mothers against decapentaplegic pathway and angiogenesis-associated microRNAs.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Biomarkers; Cell Line, Tumor; Disease Model | 2015 |
Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages.
Topics: Animals; Biomarkers; Breast Neoplasms; Cell Communication; Cell Line, Tumor; Cell Survival; Disease | 2016 |
Antitumor activity of emodin against pancreatic cancer depends on its dual role: promotion of apoptosis and suppression of angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Emodin; Enzyme | 2012 |
Emodin inhibits vascular endothelial growth factor-A-induced angiogenesis by blocking receptor-2 (KDR/Flk-1) phosphorylation.
Topics: Animals; Biocompatible Materials; Cell Cycle; Cell Movement; Cell Proliferation; Collagen; Dose-Resp | 2006 |
Anthraquinone derivative emodin inhibits tumor-associated angiogenesis through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured | 2006 |
Evaluation of the anti-angiogenic effect of aloe-emodin.
Topics: Angiogenesis Inhibitors; Animals; Anthraquinones; Cattle; Cell Differentiation; Cell Line; Cell Move | 2006 |