emodin has been researched along with Alveolitis, Fibrosing in 9 studies
Emodin: Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as a laxative, but is now used mainly as a tool in toxicity studies.
emodin : A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Objective To explore the role of transforming growth factor-β1 (TGF-β1)/a disintegrin-like and metalloproteinase with thrombospondin type 1 motif (ADAMTS-1) signaling pathway in emodin's anti-pulmonary fibrosis." | 7.83 | [Emodin alleviates pulmonary fibrosis through inactivation of TGF-β1/ADAMTS-1 signaling pathway in rats]. ( He, J; Liu, L; Long, X; Qian, H; Wang, Z; Xiao, H; Xie, M, 2016) |
| "The aim of this article was to investigate the mechanisms of emodin in antagonizing against organ fibrosis, and to illustrate that emodin can be an effective Chinese herbal preparation for treatment of organ fibrosis." | 7.73 | [Emodin and organ fibrosis]. ( Gao, ZQ; Wang, CH, 2005) |
| "Emodin is a natural anthraquinone compound, which is the main component found in the traditional Chinese herb Polygonum cuspidatum." | 5.91 | Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis. ( Fan, L; Jiang, G; Ni, K; Tong, W; Yang, J, 2023) |
| "Emodin is a major ingredient of rhubarb and has been proven to protect against lung disruptions." | 5.48 | Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats. ( Liu, XL; Tian, SL; Xu, QB; Yang, Y, 2018) |
| "Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with few treatment options and poor prognosis." | 5.43 | Emodin alleviates bleomycin-induced pulmonary fibrosis in rats. ( Cheng, W; Guan, R; Guo, Y; Jiang, L; Shen, L; Song, N; Wang, X; Yan, X; Zhao, X, 2016) |
| "Emodin treatment (10 and 20 mg/kg per day, p." | 5.35 | Inhibitory effect of emodin on bleomycin-induced pulmonary fibrosis in mice. ( Chen, XH; Guan, WD; Hu, JM; Jin, GY; Mo, ZY; Sun, RS; Yang, ZF; Zhong, NS, 2009) |
| "Objective To explore the role of transforming growth factor-β1 (TGF-β1)/a disintegrin-like and metalloproteinase with thrombospondin type 1 motif (ADAMTS-1) signaling pathway in emodin's anti-pulmonary fibrosis." | 3.83 | [Emodin alleviates pulmonary fibrosis through inactivation of TGF-β1/ADAMTS-1 signaling pathway in rats]. ( He, J; Liu, L; Long, X; Qian, H; Wang, Z; Xiao, H; Xie, M, 2016) |
| "The aim of this article was to investigate the mechanisms of emodin in antagonizing against organ fibrosis, and to illustrate that emodin can be an effective Chinese herbal preparation for treatment of organ fibrosis." | 3.73 | [Emodin and organ fibrosis]. ( Gao, ZQ; Wang, CH, 2005) |
| "Emodin is a natural anthraquinone compound, which is the main component found in the traditional Chinese herb Polygonum cuspidatum." | 1.91 | Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis. ( Fan, L; Jiang, G; Ni, K; Tong, W; Yang, J, 2023) |
| "Silicosis is a fatal pulmonary disease caused by the inhalation of silica dust, and characterized by inflammation and fibrosis of the lung, with no effective treatment to date." | 1.62 | Emodin attenuates silica-induced lung injury by inhibition of inflammation, apoptosis and epithelial-mesenchymal transition. ( Jia, Q; Lavin, MF; Li, C; Nie, X; Pang, X; Peng, C; Shao, H; Shao, L; Xia, Q; Yan, H; Yeo, AJ; Yu, G, 2021) |
| "Emodin is a major ingredient of rhubarb and has been proven to protect against lung disruptions." | 1.48 | Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats. ( Liu, XL; Tian, SL; Xu, QB; Yang, Y, 2018) |
| "Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with few treatment options and poor prognosis." | 1.43 | Emodin alleviates bleomycin-induced pulmonary fibrosis in rats. ( Cheng, W; Guan, R; Guo, Y; Jiang, L; Shen, L; Song, N; Wang, X; Yan, X; Zhao, X, 2016) |
| "Emodin treatment (10 and 20 mg/kg per day, p." | 1.35 | Inhibitory effect of emodin on bleomycin-induced pulmonary fibrosis in mice. ( Chen, XH; Guan, WD; Hu, JM; Jin, GY; Mo, ZY; Sun, RS; Yang, ZF; Zhong, NS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 6 |
| Jiang, G | 3 |
| Ni, K | 3 |
| Fan, L | 3 |
| Tong, W | 3 |
| Pang, X | 1 |
| Shao, L | 1 |
| Nie, X | 1 |
| Yan, H | 1 |
| Li, C | 1 |
| Yeo, AJ | 1 |
| Lavin, MF | 1 |
| Xia, Q | 1 |
| Shao, H | 1 |
| Yu, G | 1 |
| Jia, Q | 1 |
| Peng, C | 1 |
| Tian, SL | 1 |
| Yang, Y | 1 |
| Liu, XL | 1 |
| Xu, QB | 1 |
| Liu, L | 1 |
| Qian, H | 1 |
| Xiao, H | 1 |
| He, J | 1 |
| Xie, M | 1 |
| Wang, Z | 1 |
| Long, X | 1 |
| Guan, R | 2 |
| Zhao, X | 2 |
| Wang, X | 2 |
| Song, N | 2 |
| Guo, Y | 1 |
| Yan, X | 1 |
| Jiang, L | 1 |
| Cheng, W | 1 |
| Shen, L | 2 |
| Zhu, J | 1 |
| Wang, J | 2 |
| Xia, C | 1 |
| Chen, Y | 1 |
| Zhu, D | 1 |
| Chen, XH | 1 |
| Sun, RS | 1 |
| Hu, JM | 1 |
| Mo, ZY | 1 |
| Yang, ZF | 1 |
| Jin, GY | 1 |
| Guan, WD | 1 |
| Zhong, NS | 1 |
| Qu, Y | 1 |
| Yao, P | 1 |
| Li, TQ | 1 |
| Gao, ZQ | 1 |
| Wang, CH | 1 |
9 other studies available for emodin and Alveolitis, Fibrosing
| Article | Year |
|---|---|
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin inhibiting epithelial-mesenchymal transition in pulmonary fibrosis through the c-MYC/miR-182-5p/ZEB2 axis.
Topics: Animals; Bleomycin; Emodin; Epithelial-Mesenchymal Transition; Mice; MicroRNAs; Pulmonary Fibrosis | 2023 |
Emodin attenuates silica-induced lung injury by inhibition of inflammation, apoptosis and epithelial-mesenchymal transition.
Topics: A549 Cells; Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Pr | 2021 |
Emodin Attenuates Bleomycin-Induced Pulmonary Fibrosis via Anti-Inflammatory and Anti-Oxidative Activities in Rats.
Topics: A549 Cells; Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Cell Culture Techniques; Cyt | 2018 |
[Emodin alleviates pulmonary fibrosis through inactivation of TGF-β1/ADAMTS-1 signaling pathway in rats].
Topics: ADAMTS1 Protein; Animals; Collagen Type I; Collagen Type III; Drugs, Chinese Herbal; Emodin; Humans; | 2016 |
Emodin alleviates bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Differentiation; | 2016 |
Emodin ameliorates bleomycin-induced pulmonary fibrosis in rats by suppressing epithelial-mesenchymal transition and fibroblast activation.
Topics: A549 Cells; Alveolar Epithelial Cells; Animals; Bleomycin; Cell Differentiation; Cell Line, Tumor; C | 2016 |
Inhibitory effect of emodin on bleomycin-induced pulmonary fibrosis in mice.
Topics: Animals; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Proliferation; Collagen; Cytokines; Disease M | 2009 |
[Effects of emodin on lung fibroblast proliferation and cell cycle in vitro].
Topics: Cell Cycle; Cell Division; Cells, Cultured; Depression, Chemical; Emodin; Fetus; Fibroblasts; Flow C | 2004 |
[Emodin and organ fibrosis].
Topics: Animals; Emodin; Fibrosis; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Liver Cirrhosis; Phy | 2005 |